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Tag Content
iUUCD ID IUUC-Eca-034036
Ensembl Protein ID ENSECAP00000011693.1
UniProt Accession F6ZLD4; F6ZLD4_HORSE
Protein Name Autophagy protein 5
Gene Name ATG5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSECAG00000013971.1 ENSECAT00000014616.1 ENSECAP00000011693.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/Other 23.99 1.00e-08 55.50 IUUC-Sce-106216
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Equus caballus
Functional Description
(View)

Functional Description



     Involved in autophagic vesicle formation.
Involved in autophagic vesicle formation.
Protein Sequence
(Fasta)
MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM 60
RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI TVHFKSFPEK DLLHCPSKDA 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Eca-034036|E3,Cullin RING/Other|Equus caballus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTTTGGCTTT GGTTGATAAA AGAATTTAGC CTATATGTAC TGCTTTAACC ACTGGAAGAA 60
TGACAGATGA CAAAGATGTG CTTCGAGATG TGTGGTTTGG ACGAATTCCA ACTTGCTTCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Eca-034036|E3,Cullin RING/Other|Equus caballus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR007239--Atg5

Pfam

PF04106--APG5

Gene Ontology

GO:0034274--C:Atg12-Atg5-Atg16 complex
GO:0005776--C:autophagosome
GO:0005930--C:axoneme
GO:0044233--C:ER-mitochondrion membrane contact site
GO:0034045--C:pre-autophagosomal structure membrane
GO:0035973--P:aggrephagy
GO:0019883--P:antigen processing and presentation of endogenous antigen
GO:0000045--P:autophagosome assembly
GO:0001974--P:blood vessel remodeling
GO:0006501--P:C-terminal protein lipidation
GO:0019725--P:cellular homeostasis
GO:0006995--P:cellular response to nitrogen starvation
GO:0071500--P:cellular response to nitrosative stress
GO:0060047--P:heart contraction
GO:0000422--P:mitophagy
GO:0043066--P:negative regulation of apoptotic process
GO:2000619--P:negative regulation of histone H4-K16 acetylation
GO:0050765--P:negative regulation of phagocytosis
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000378--P:negative regulation of reactive oxygen species metabolic process
GO:0039689--P:negative stranded viral RNA replication
GO:0045060--P:negative thymic T cell selection
GO:0044804--P:nucleophagy
GO:0048840--P:otolith development
GO:0070257--P:positive regulation of mucus secretion
GO:0061739--P:protein lipidation involved in autophagosome assembly
GO:1902017--P:regulation of cilium assembly
GO:0002739--P:regulation of cytokine secretion involved in immune response
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0042493--P:response to drug
GO:0009620--P:response to fungus
GO:0042311--P:vasodilation
GO:0055015--P:ventricular cardiac muscle cell development

KEGG ecb:100066344
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000583 Aegilops tauschii 32.94 5.00e-25 109.00
IUUC-Aml-002403 Ailuropoda melanoleuca 97.83 1.00e-157 548.00
IUUC-Atr-002645 Amborella trichopoda 27.00 4.00e-24 105.00
IUUC-Apl-003611 Anas platyrhynchos 89.45 4.00e-153 533.00
IUUC-Aca-004411 Anolis carolinensis 89.21 4.00e-150 523.00
IUUC-Aly-005636 Arabidopsis lyrata 27.27 2.00e-27 116.00
IUUC-Ath-006959 Arabidopsis thaliana 27.58 1.00e-27 116.00
IUUC-Ago-007978 Ashbya gossypii 27.67 1.00e-07 50.10
IUUC-Acl-008328 Aspergillus clavatus 26.10 6.00e-20 90.90
IUUC-Afl-008638 Aspergillus flavus 25.24 8.00e-25 107.00
IUUC-Afu-009042 Aspergillus fumigatus 26.28 2.00e-26 112.00
IUUC-Ani-009364 Aspergillus nidulans 30.05 2.00e-23 103.00
IUUC-Aor-009889 Aspergillus oryzae 25.24 9.00e-25 107.00
IUUC-Ate-010511 Aspergillus terreus 31.18 5.00e-10 55.80
IUUC-Ame-011644 Astyanax mexicanus 86.08 8.00e-38 147.00
IUUC-Bgr-012153 Blumeria graminis 28.15 1.00e-17 83.60
IUUC-Bta-012360 Bos taurus 98.74 2.00e-87 313.00
IUUC-Bci-013723 Botrytis cinerea 26.99 2.00e-16 79.00
IUUC-Bdi-014520 Brachypodium distachyon 23.26 5.00e-22 98.20
IUUC-Bol-016053 Brassica oleracea 26.87 1.00e-29 123.00
IUUC-Bra-017072 Brassica rapa 26.65 1.00e-29 123.00
IUUC-Cel-018529 Caenorhabditis elegans 35.64 3.00e-38 151.00
IUUC-Cja-019569 Callithrix jacchus 98.55 3.00e-159 553.00
IUUC-Cfa-020473 Canis familiaris 98.91 1.00e-159 555.00
IUUC-Cpo-021421 Cavia porcellus 97.09 2.00e-157 547.00
IUUC-Cre-022862 Chlamydomonas reinhardtii 29.31 3.00e-18 84.70
IUUC-Csa-024197 Chlorocebus sabaeus 98.18 2.00e-158 551.00
IUUC-Cho-024521 Choloepus hoffmanni 95.82 3.00e-132 463.00
IUUC-Cin-025119 Ciona intestinalis 45.45 2.00e-64 238.00
IUUC-Csv-026192 Ciona savignyi 46.64 6.00e-66 243.00
IUUC-Cgl-026686 Colletotrichum gloeosporioides 23.50 2.00e-09 56.20
IUUC-Dre-028466 Danio rerio 80.36 5.00e-135 473.00
IUUC-Dse-031228 Dothistroma septosporum 27.12 1.00e-31 129.00
IUUC-Dme-031703 Drosophila melanogaster 48.34 7.00e-73 266.00
IUUC-Ete-032482 Echinops telfairi 97.07 6.00e-134 469.00
IUUC-Eeu-035235 Erinaceus europaeus 99.37 2.00e-87 315.00
IUUC-Fca-036263 Felis catus 98.55 3.00e-159 553.00
IUUC-Fal-037064 Ficedula albicollis 89.45 2.00e-153 534.00
IUUC-Fox-037813 Fusarium oxysporum 25.80 2.00e-16 79.00
IUUC-Fso-038139 Fusarium solani 26.67 6.00e-18 84.30
IUUC-Gmo-039509 Gadus morhua 80.63 1.00e-111 394.00
IUUC-Ggr-040111 Gaeumannomyces graminis 25.39 3.00e-14 72.40
IUUC-Gga-040517 Gallus gallus 88.73 1.00e-151 528.00
IUUC-Gac-042270 Gasterosteus aculeatus 70.80 5.00e-117 413.00
IUUC-Gma-044400 Glycine max 36.14 5.00e-24 104.00
IUUC-Ggo-045048 Gorilla gorilla 97.45 5.00e-157 546.00
IUUC-Hsa-046744 Homo sapiens 98.18 2.00e-158 550.00
IUUC-Kpa-049174 Komagataella pastoris 24.67 2.00e-14 72.80
IUUC-Lch-049475 Latimeria chalumnae 88.36 3.00e-148 516.00
IUUC-Lpe-051283 Leersia perrieri 36.17 6.00e-24 106.00
IUUC-Loc-052446 Lepisosteus oculatus 83.27 3.00e-142 497.00
IUUC-Lma-053278 Leptosphaeria maculans 27.76 3.00e-30 125.00
IUUC-Laf-054020 Loxodonta africana 97.11 4.00e-157 546.00
IUUC-Mcc-055176 Macaca mulatta 98.18 2.00e-158 550.00
IUUC-Mor-057164 Magnaporthe oryzae 26.98 2.00e-17 83.20
IUUC-Mpo-057428 Magnaporthe poae 26.27 1.00e-13 70.10
IUUC-Mtr-058424 Medicago truncatula 35.98 7.00e-24 103.00
IUUC-Mla-058872 Melampsora laricipopulina 29.74 6.00e-30 124.00
IUUC-Mga-059859 Meleagris gallopavo 88.73 1.00e-151 528.00
IUUC-Mmr-061482 Microcebus murinus 98.18 9.00e-159 551.00
IUUC-Mdo-062371 Monodelphis domestica 94.55 1.00e-159 555.00
IUUC-Mmu-063139 Mus musculus 97.45 9.00e-158 548.00
IUUC-Mac-065332 Musa acuminata 26.16 1.00e-26 114.00
IUUC-Mpu-066783 Mustela putorius furo 98.91 3.00e-159 553.00
IUUC-Mlu-068165 Myotis lucifugus 95.67 2.00e-154 538.00
IUUC-Nfi-068578 Neosartorya fischeri 27.39 7.00e-28 117.00
IUUC-Ncr-068636 Neurospora crassa 23.86 5.00e-12 65.10
IUUC-Nle-069740 Nomascus leucogenys 98.18 2.00e-158 550.00
IUUC-Opr-070802 Ochotona princeps 98.11 3.00e-86 311.00
IUUC-Ont-072222 Oreochromis niloticus 78.18 6.00e-135 473.00
IUUC-Oan-072760 Ornithorhynchus anatinus 93.91 3.00e-112 397.00
IUUC-Ocu-074844 Oryctolagus cuniculus 94.77 2.00e-97 347.00
IUUC-Oba-075834 Oryza barthii 33.90 3.00e-25 108.00
IUUC-Obr-076230 Oryza brachyantha 32.69 7.00e-15 74.30
IUUC-Ogl-077554 Oryza glaberrima 33.90 4.00e-25 108.00
IUUC-Ogu-078687 Oryza glumaepatula 33.90 2.00e-25 109.00
IUUC-Oin-079677 Oryza indica 26.39 1.00e-26 114.00
IUUC-Olo-081078 Oryza longistaminata 36.81 2.00e-25 110.00
IUUC-Ome-081548 Oryza meridionalis 34.46 5.00e-28 119.00
IUUC-Oni-082050 Oryza nivara 34.46 8.00e-26 110.00
IUUC-Opu-083609 Oryza punctata 34.27 6.00e-26 111.00
IUUC-Oru-085057 Oryza rufipogon 34.46 1.00e-25 110.00
IUUC-Osa-085917 Oryza sativa 34.46 1.00e-25 110.00
IUUC-Ola-087032 Oryzias latipes 79.27 4.00e-134 470.00
IUUC-Olu-087877 Ostreococcus lucimarinus 28.24 5.00e-03 33.50
IUUC-Oga-088468 Otolemur garnettii 97.11 1.00e-161 561.00
IUUC-Oar-089751 Ovis aries 97.82 3.00e-158 550.00
IUUC-Ptr-091064 Pan troglodytes 98.18 2.00e-158 550.00
IUUC-Pan-092505 Papio anubis 97.47 9.00e-157 545.00
IUUC-Psi-093086 Pelodiscus sinensis 90.58 5.00e-154 536.00
IUUC-Pno-094825 Phaeosphaeria nodorum 28.47 7.00e-27 114.00
IUUC-Ppa-095419 Physcomitrella patens 33.73 1.00e-25 110.00
IUUC-Pfo-096224 Poecilia formosa 78.55 2.00e-133 467.00
IUUC-Pab-098501 Pongo abelii 97.82 2.00e-157 547.00
IUUC-Pop-099243 Populus trichocarpa 27.96 2.00e-25 109.00
IUUC-Ppe-101255 Prunus persica 26.76 1.00e-27 117.00
IUUC-Pva-102828 Pteropus vampyrus 97.45 2.00e-157 547.00
IUUC-Pgr-103672 Puccinia graminis 29.93 1.00e-25 110.00
IUUC-Ptt-104013 Puccinia triticina 27.36 9.00e-22 97.80
IUUC-Pyt-104615 Pyrenophora triticirepentis 28.01 1.00e-28 119.00
IUUC-Rno-106089 Rattus norvegicus 95.10 2.00e-135 474.00
IUUC-Sce-106216 Saccharomyces cerevisiae 23.99 8.00e-12 63.90
IUUC-Sha-106484 Sarcophilus harrisii 94.91 3.00e-159 553.00
IUUC-Sja-107699 Schizosaccharomyces japonicus 27.44 2.00e-26 112.00
IUUC-Spo-108177 Schizosaccharomyces pombe 28.11 2.00e-22 99.40
IUUC-Ssl-108475 Sclerotinia sclerotiorum 27.34 2.00e-16 79.00
IUUC-Smo-109473 Selaginella moellendorffii 27.52 6.00e-24 104.00
IUUC-Sit-110736 Setaria italica 33.51 3.00e-29 122.00
IUUC-Sly-111657 Solanum lycopersicum 37.20 9.00e-28 117.00
IUUC-Sar-113050 Sorex araneus 82.43 7.00e-108 382.00
IUUC-Sbi-114258 Sorghum bicolor 33.92 4.00e-26 112.00
IUUC-Sre-114902 Sporisorium reilianum 31.19 3.00e-23 102.00
IUUC-Ssc-116166 Sus scrofa 91.27 7.00e-148 516.00
IUUC-Tgu-116814 Taeniopygia guttata 88.73 4.00e-152 530.00
IUUC-Tru-118172 Takifugu rubripes 79.71 4.00e-134 469.00
IUUC-Tsy-119010 Tarsius syrichta 84.00 1.00e-134 472.00
IUUC-Tni-120397 Tetraodon nigroviridis 80.00 7.00e-102 362.00
IUUC-Tca-121283 Theobroma cacao 28.21 2.00e-28 120.00
IUUC-Tvi-122545 Trichoderma virens 24.05 2.00e-14 72.80
IUUC-Tae-122685 Triticum aestivum 32.16 9.00e-25 107.00
IUUC-Tur-126407 Triticum urartu 34.67 4.00e-25 108.00
IUUC-Tme-126913 Tuber melanosporum 31.58 2.00e-40 159.00
IUUC-Tbe-127738 Tupaia belangeri 90.82 5.00e-106 376.00
IUUC-Ttr-128528 Tursiops truncatus 97.82 8.00e-158 548.00
IUUC-Uma-129625 Ustilago maydis 28.11 1.00e-20 94.40
IUUC-Vda-129906 Verticillium dahliae 23.90 3.00e-11 62.00
IUUC-Vpa-130223 Vicugna pacos 96.73 2.00e-152 530.00
IUUC-Vvi-131617 Vitis vinifera 35.37 3.00e-25 108.00
IUUC-Xtr-132288 Xenopus tropicalis 86.55 1.00e-144 504.00
IUUC-Xma-134214 Xiphophorus maculatus 82.38 4.00e-97 347.00
IUUC-Yli-134377 Yarrowia lipolytica 24.88 2.00e-12 66.20
IUUC-Zma-135108 Zea mays 34.72 6.00e-24 104.00
Created Date 25-Jun-2017

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