iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011879

Ensembl Protein ID

ENSAMXP00000022202.1

UniProt Accession

W5LQA5; W5LQA5_ASTMX

Genbank Protein ID

ENSAMXP00000022202

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

APWO01079816

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000021559.1	ENSAMXT00000022202.1	ENSAMXP00000022202.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.60e-09	37.4	189	236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C++
   Q: 189  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCTQ 236
           69*.*******99..*********99***********...999997.******86 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MATAIYLEHY LDSIENLPCE LQRNFTLMRE LDNRTEEKKG EIDKLAEEYI KNVRNLASEQ 60
RVEHLQKIQN AYSKCKEFSD DKVQLAMQTY EMVDKHIRRL DADLARFENE LKEKLDVGGY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGGAAAGA ATGCAAAACC ACAACGTCTC AACCAATGGG AACGATGCGG GTCATGAATT 60
ATTAATAAGA TGCCAATGTT GTTCTGGATC ACGCGTTGAG AAAAACATTA AATCTCTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	75.44	2.00e-91	327.00
IUUC-Apl-003516	Anas platyrhynchos	74.15	7.00e-85	306.00
IUUC-Aca-005009	Anolis carolinensis	76.67	7.00e-103	366.00
IUUC-Bta-012590	Bos taurus	77.19	6.00e-96	343.00
IUUC-Cja-019518	Callithrix jacchus	75.93	3.00e-105	374.00
IUUC-Cfa-020620	Canis familiaris	78.42	2.00e-108	384.00
IUUC-Cpo-022085	Cavia porcellus	76.37	2.00e-98	351.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	36.93	3.00e-29	122.00
IUUC-Csa-023421	Chlorocebus sabaeus	76.35	2.00e-99	354.00
IUUC-Dre-027588	Danio rerio	90.91	1.00e-121	428.00
IUUC-Eca-033493	Equus caballus	73.28	8.00e-97	345.00
IUUC-Fal-036998	Ficedula albicollis	75.32	4.00e-98	350.00
IUUC-Gmo-039035	Gadus morhua	88.38	4.00e-120	423.00
IUUC-Gga-040578	Gallus gallus	75.42	8.00e-105	372.00
IUUC-Gac-042172	Gasterosteus aculeatus	84.23	2.00e-123	434.00
IUUC-Hsa-045965	Homo sapiens	76.35	2.00e-99	354.00
IUUC-Loc-052725	Lepisosteus oculatus	83.82	4.00e-106	377.00
IUUC-Mcc-055455	Macaca mulatta	74.78	1.00e-91	328.00
IUUC-Mtr-058089	Medicago truncatula	33.33	1.00e-33	135.00
IUUC-Mga-059312	Meleagris gallopavo	72.06	1.00e-83	301.00
IUUC-Mmr-061351	Microcebus murinus	75.00	4.00e-91	327.00
IUUC-Mdo-062282	Monodelphis domestica	76.76	4.00e-101	360.00
IUUC-Mmu-063201	Mus musculus	75.93	3.00e-104	370.00
IUUC-Mpu-066302	Mustela putorius furo	76.76	3.00e-100	357.00
IUUC-Mlu-068192	Myotis lucifugus	76.35	2.00e-101	361.00
IUUC-Ont-072055	Oreochromis niloticus	89.63	7.00e-116	409.00
IUUC-Oan-073652	Ornithorhynchus anatinus	77.63	2.00e-97	347.00
IUUC-Ocu-073871	Oryctolagus cuniculus	75.21	3.00e-100	357.00
IUUC-Ola-087103	Oryzias latipes	87.50	2.00e-109	388.00
IUUC-Oga-088066	Otolemur garnettii	68.29	7.00e-86	309.00
IUUC-Ptr-091665	Pan troglodytes	76.35	2.00e-99	354.00
IUUC-Pan-091875	Papio anubis	76.35	2.00e-99	354.00
IUUC-Psi-093904	Pelodiscus sinensis	72.73	7.00e-90	322.00
IUUC-Pfo-096981	Poecilia formosa	88.80	2.00e-115	407.00
IUUC-Pva-102282	Pteropus vampyrus	75.93	5.00e-106	376.00
IUUC-Rno-105646	Rattus norvegicus	75.93	3.00e-104	370.00
IUUC-Sha-107031	Sarcophilus harrisii	75.76	4.00e-94	337.00
IUUC-Smo-109441	Selaginella moellendorffii	34.27	5.00e-41	160.00
IUUC-Sbi-114826	Sorghum bicolor	34.54	3.00e-36	144.00
IUUC-Tgu-116837	Taeniopygia guttata	74.14	1.00e-97	348.00
IUUC-Tru-117974	Takifugu rubripes	89.17	4.00e-111	393.00
IUUC-Tni-120024	Tetraodon nigroviridis	88.80	4.00e-101	360.00
IUUC-Tae-123043	Triticum aestivum	34.12	5.00e-38	150.00
IUUC-Xtr-132189	Xenopus tropicalis	77.18	4.00e-107	380.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence