iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033982

UUCD1 version

UUC-EqC-00260

Ensembl Protein ID

ENSECAP00000013336.1

UniProt Accession

F6U033; F6U033_HORSE

Protein Name

Uncharacterized protein

Gene Name

TBL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015585.1	ENSECAT00000016510.1	ENSECAP00000013336.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-20	73.1	89	122
UBD/Beta-Prp	8.20e-42	143.5	75	309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H++ ++c++f s+ ++l++++dD t+++W+++++
   Q: 89   HSGNISCMDFsSNgKYLATCADDRTVRIWSTKDF 122
           9**********777***************98775 PP

UBD/Beta-Prp

   S: 37   wdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcvhtlkghedsvlslsfspsg.dklvsGshdrtirv 120
           +++t   l + l++h++ +++++fs++gk+l+t+++Drt+++w+ +         +  + + d +++++fsp+   ++v   + +t+rv
   Q: 75   HNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKdflqREHRSMRANVELDHATLVRFSPDCrAFIVWLANGDTLRV 163
           566777778999*******************************7773433333333344678999*******655************** PP
   S: 121  wdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsld 201
           +++ +++            + ++h++ +  +++ ++g+ ++++s D+t+ +W+l  g++l t   ++ + ++   +++ +++++s++  
   Q: 164  FKMTKREDGGYtftatpedFPKKHKAPIINIAIADTGKFIMTASSDTTILIWNL-KGQVLSTINTNQMNNIHAA-ISPCSRFVASCGFT 250
           *999887665567789999***********************************.7888888877688888765.678899******** PP
   S: 202  gtvklwdlqtgec........vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
            +vk+w++  g+           +l+gh++ v+  +fs+++ r++s+s+Dg+ ++Wd++
   Q: 251  PDVKVWEVCFGKKgdfqevvrAFELKGHSAAVLFFAFSNDSRRMASVSKDGTWKLWDTD 309
           ********955555557777788999******************************865 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MELPQIPELM GLSLLLGLLA LMATAAVARG WLRAEEETCG GSAGQKANGL PLDKSSRSKK 60
QKQHQRIRKE KPQQHNFTHR LLAAALKSHS GNISCMDFSS NGKYLATCAD DRTVRIWSTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCGCCCC CGAGACGCTC CAACGGCCAG GCCTCGCCCC GCGTGCGTGC GCGGCCCCGC 60
GGAGGCGTGC AGGCGCCCGC GTAGCCAGAG GCTGAGGTGG CAGAGGCCCC GCCAACATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005783--C:endoplasmic reticulum
GO:0003723--F:RNA binding
GO:0042149--P:cellular response to glucose starvation
GO:0071456--P:cellular response to hypoxia
GO:0030968--P:endoplasmic reticulum unfolded protein response

KEGG

ecb:100059856

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000109	Aegilops tauschii	32.32	6.00e-23	100.00
IUUC-Aml-002212	Ailuropoda melanoleuca	95.26	0.00e+00	763.00
IUUC-Atr-002903	Amborella trichopoda	29.75	3.00e-37	149.00
IUUC-Apl-003635	Anas platyrhynchos	74.11	1.00e-163	568.00
IUUC-Aca-004472	Anolis carolinensis	74.36	1.00e-166	579.00
IUUC-Aly-005761	Arabidopsis lyrata	29.76	4.00e-39	155.00
IUUC-Ath-007476	Arabidopsis thaliana	30.56	2.00e-39	156.00
IUUC-Ame-011221	Astyanax mexicanus	66.01	6.00e-147	513.00
IUUC-Bta-013186	Bos taurus	92.15	0.00e+00	764.00
IUUC-Bdi-014298	Brachypodium distachyon	30.92	1.00e-39	157.00
IUUC-Bol-015192	Brassica oleracea	28.53	8.00e-37	147.00
IUUC-Bra-017078	Brassica rapa	29.10	9.00e-38	150.00
IUUC-Cel-018602	Caenorhabditis elegans	31.38	3.00e-58	219.00
IUUC-Cja-018909	Callithrix jacchus	88.81	0.00e+00	719.00
IUUC-Cfa-020970	Canis familiaris	93.72	0.00e+00	781.00
IUUC-Cpo-022215	Cavia porcellus	88.28	0.00e+00	698.00
IUUC-Csa-023530	Chlorocebus sabaeus	88.14	0.00e+00	734.00
IUUC-Cho-024598	Choloepus hoffmanni	94.76	4.00e-142	497.00
IUUC-Cin-025486	Ciona intestinalis	50.13	3.00e-105	375.00
IUUC-Csv-025930	Ciona savignyi	48.30	5.00e-94	337.00
IUUC-Dre-027507	Danio rerio	66.01	1.00e-147	516.00
IUUC-Dno-029726	Dasypus novemcinctus	90.43	0.00e+00	753.00
IUUC-Dor-030501	Dipodomys ordii	78.70	6.00e-180	623.00
IUUC-Ete-032794	Echinops telfairi	90.15	5.00e-137	479.00
IUUC-Eeu-035090	Erinaceus europaeus	91.82	4.00e-139	487.00
IUUC-Fca-035944	Felis catus	95.27	0.00e+00	805.00
IUUC-Fal-036992	Ficedula albicollis	66.67	1.00e-149	523.00
IUUC-Gmo-038710	Gadus morhua	64.25	6.00e-145	506.00
IUUC-Gga-040885	Gallus gallus	70.65	8.00e-113	399.00
IUUC-Gac-041922	Gasterosteus aculeatus	64.63	4.00e-150	524.00
IUUC-Gma-044233	Glycine max	30.30	1.00e-37	150.00
IUUC-Ggo-045172	Gorilla gorilla	90.59	0.00e+00	719.00
IUUC-Hsa-045711	Homo sapiens	89.71	0.00e+00	742.00
IUUC-Itr-048196	Ictidomys tridecemlineatus	90.81	0.00e+00	736.00
IUUC-Lch-049739	Latimeria chalumnae	71.06	1.00e-162	566.00
IUUC-Lpe-050795	Leersia perrieri	26.59	1.00e-23	104.00
IUUC-Loc-052113	Lepisosteus oculatus	72.99	3.00e-154	537.00
IUUC-Laf-053751	Loxodonta africana	90.58	0.00e+00	773.00
IUUC-Mcc-055022	Macaca mulatta	89.09	0.00e+00	731.00
IUUC-Meu-056003	Macropus eugenii	73.98	1.00e-163	569.00
IUUC-Mtr-058500	Medicago truncatula	29.43	2.00e-36	146.00
IUUC-Mga-059278	Meleagris gallopavo	69.77	2.00e-124	438.00
IUUC-Mmr-061148	Microcebus murinus	91.70	0.00e+00	752.00
IUUC-Mdo-063002	Monodelphis domestica	70.98	1.00e-165	575.00
IUUC-Mmu-063607	Mus musculus	88.34	0.00e+00	716.00
IUUC-Mac-065359	Musa acuminata	27.69	2.00e-36	146.00
IUUC-Mpu-066323	Mustela putorius furo	95.60	0.00e+00	639.00
IUUC-Mlu-067946	Myotis lucifugus	94.17	0.00e+00	794.00
IUUC-Nle-069019	Nomascus leucogenys	89.26	0.00e+00	735.00
IUUC-Opr-071047	Ochotona princeps	89.69	0.00e+00	733.00
IUUC-Ont-071694	Oreochromis niloticus	66.95	5.00e-150	523.00
IUUC-Oan-073474	Ornithorhynchus anatinus	57.82	7.00e-104	370.00
IUUC-Ocu-074493	Oryctolagus cuniculus	89.46	0.00e+00	718.00
IUUC-Oba-075468	Oryza barthii	27.82	2.00e-34	140.00
IUUC-Obr-076681	Oryza brachyantha	28.33	1.00e-35	144.00
IUUC-Ogl-077870	Oryza glaberrima	27.82	2.00e-34	140.00
IUUC-Ogu-078536	Oryza glumaepatula	27.82	2.00e-34	140.00
IUUC-Oin-080175	Oryza indica	27.82	2.00e-34	140.00
IUUC-Olo-080796	Oryza longistaminata	28.27	7.00e-33	134.00
IUUC-Oni-082076	Oryza nivara	27.82	2.00e-34	140.00
IUUC-Opu-083267	Oryza punctata	28.07	6.00e-35	141.00
IUUC-Oru-084553	Oryza rufipogon	27.82	2.00e-34	140.00
IUUC-Osa-085389	Oryza sativa	27.82	2.00e-34	140.00
IUUC-Ola-086414	Oryzias latipes	64.99	2.00e-146	512.00
IUUC-Oga-088656	Otolemur garnettii	90.36	0.00e+00	760.00
IUUC-Oar-089719	Ovis aries	92.31	0.00e+00	723.00
IUUC-Ptr-091087	Pan troglodytes	89.49	0.00e+00	739.00
IUUC-Pan-091709	Papio anubis	89.26	0.00e+00	744.00
IUUC-Psi-093265	Pelodiscus sinensis	72.11	3.00e-171	594.00
IUUC-Pma-094482	Petromyzon marinus	58.43	8.00e-58	215.00
IUUC-Ppa-095365	Physcomitrella patens	28.93	2.00e-37	149.00
IUUC-Pfo-097494	Poecilia formosa	65.27	1.00e-147	516.00
IUUC-Pab-098362	Pongo abelii	89.49	0.00e+00	740.00
IUUC-Pop-099163	Populus trichocarpa	29.65	6.00e-32	132.00
IUUC-Pca-101019	Procavia capensis	88.55	1.00e-154	539.00
IUUC-Ppe-102101	Prunus persica	27.86	4.00e-37	149.00
IUUC-Pva-102849	Pteropus vampyrus	95.00	0.00e+00	763.00
IUUC-Rno-105511	Rattus norvegicus	88.57	0.00e+00	716.00
IUUC-Sha-107265	Sarcophilus harrisii	70.75	2.00e-168	585.00
IUUC-Smo-108866	Selaginella moellendorffii	31.66	2.00e-35	142.00
IUUC-Sit-110806	Setaria italica	28.61	1.00e-35	144.00
IUUC-Sly-110994	Solanum lycopersicum	30.17	7.00e-35	141.00
IUUC-Stu-112493	Solanum tuberosum	35.79	1.00e-30	126.00
IUUC-Sar-113628	Sorex araneus	88.81	0.00e+00	715.00
IUUC-Sbi-114397	Sorghum bicolor	29.15	4.00e-36	145.00
IUUC-Ssc-116418	Sus scrofa	92.60	0.00e+00	785.00
IUUC-Tgu-117054	Taeniopygia guttata	68.35	6.00e-156	543.00
IUUC-Tru-118504	Takifugu rubripes	68.83	2.00e-157	548.00
IUUC-Tni-120254	Tetraodon nigroviridis	68.46	5.00e-156	543.00
IUUC-Tca-121085	Theobroma cacao	29.89	4.00e-37	149.00
IUUC-Tae-124320	Triticum aestivum	29.97	2.00e-39	156.00
IUUC-Tur-126756	Triticum urartu	27.72	1.00e-32	134.00
IUUC-Tbe-127903	Tupaia belangeri	87.00	0.00e+00	722.00
IUUC-Ttr-129118	Tursiops truncatus	93.30	0.00e+00	783.00
IUUC-Vvi-131125	Vitis vinifera	30.15	1.00e-36	147.00
IUUC-Xtr-132287	Xenopus tropicalis	74.79	1.00e-162	566.00
IUUC-Xma-134246	Xiphophorus maculatus	65.53	1.00e-147	515.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence