iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066323

Ensembl Protein ID

ENSMPUP00000015966.1

UniProt Accession

M3YXA6; M3YXA6_MUSPF

Genbank Protein ID

ENSMPUP00000015966

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01053270

Gene Name

TBL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000016073.1	ENSMPUT00000016210.1	ENSMPUP00000015966.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.80e-18	63.6	53	86
UBD/Beta-Prp	2.20e-43	148.5	40	271

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H++ ++c++f s+ ++l++++dD t+++W+++++
   Q: 53   HSGNISCMDFsSNgKYLATCADDRTVRIWSTKDF 86
           9**********777***************98775 PP

UBD/Beta-Prp

   S: 38   dvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcvhtlkghedsvlslsfspsg.dklvsGshdrtirvw 121
           +++   l   l++h++ +++++fs++gk+l+t+++Drt+++w+ +         +  + + d +++++fsp+   ++v   + +t+rv+
   Q: 40   NFSHRLLAGALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKdflqREHRSMRANVELDHATLVRFSPDCrAFIVWLANGDTLRVF 128
           56666678899*******************************7773433333333344678999*******655*************** PP
   S: 122  dletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldg 202
           ++ +++            + ++h++ v  + + ++g+ ++++s D+t+ +W+l  g +l t    ++   ++ ++++ +++++s++   
   Q: 129  KMTKREDGGYtftanpedFPKKHKAPVINIGIADTGKFIMTASSDTTILIWNL-KGHVLSTINT-NQMNNTHAAISPCSRFVASCGFTP 215
           999887665567889999***********************************.7888888877.888999999*************** PP
   S: 203  tvklwdlqtgec........vrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
           +vk+w++  g+           +l+gh++ v   +fs+++ r++s+s+Dg+ ++Wd
   Q: 216  DVKVWEVCFGKKsdfqevvrAFELKGHSAAVHFFAFSNDSRRMASVSKDGTWKLWD 271
           *******955555667777788999******************************9 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MTRPLLIGQK ANGLPLDKSL RSKKQKQHQR IRKEKPQQHN FSHRLLAGAL KSHSGNISCM 60
DFSSNGKYLA TCADDRTVRI WSTKDFLQRE HRSMRANVEL DHATLVRFSP DCRAFIVWLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACACGGC CTCTCCTCAT AGGCCAAAAA GCGAATGGAT TGCCACTTGA CAAGTCCTTG 60
AGATCCAAGA AGCAGAAACA GCATCAACGA ATTCGCAAGG AGAAGCCTCA ACAGCACAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0003723--F:RNA binding
GO:0042149--P:cellular response to glucose starvation
GO:0071456--P:cellular response to hypoxia
GO:0030968--P:endoplasmic reticulum unfolded protein response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000109	Aegilops tauschii	36.62	4.00e-21	94.40
IUUC-Aml-002212	Ailuropoda melanoleuca	97.47	0.00e+00	653.00
IUUC-Atr-002903	Amborella trichopoda	29.62	1.00e-37	150.00
IUUC-Apl-003635	Anas platyrhynchos	77.82	3.00e-139	487.00
IUUC-Aca-004472	Anolis carolinensis	78.29	2.00e-146	511.00
IUUC-Aly-005761	Arabidopsis lyrata	31.03	2.00e-37	150.00
IUUC-Ath-007476	Arabidopsis thaliana	31.66	1.00e-37	150.00
IUUC-Ame-011221	Astyanax mexicanus	68.26	1.00e-124	439.00
IUUC-Bta-013186	Bos taurus	85.39	8.00e-174	602.00
IUUC-Bdi-014298	Brachypodium distachyon	31.67	1.00e-37	150.00
IUUC-Bol-015192	Brassica oleracea	30.19	1.00e-35	144.00
IUUC-Bra-017078	Brassica rapa	30.84	1.00e-36	147.00
IUUC-Cel-018602	Caenorhabditis elegans	31.82	1.00e-50	193.00
IUUC-Cja-018909	Callithrix jacchus	91.19	4.00e-164	570.00
IUUC-Cfa-020970	Canis familiaris	95.91	3.00e-180	624.00
IUUC-Cpo-022215	Cavia porcellus	84.31	9.00e-162	563.00
IUUC-Csa-023530	Chlorocebus sabaeus	91.19	3.00e-170	590.00
IUUC-Cho-024598	Choloepus hoffmanni	93.95	8.00e-142	496.00
IUUC-Cin-025486	Ciona intestinalis	52.43	2.00e-87	316.00
IUUC-Csv-025930	Ciona savignyi	49.35	3.00e-79	288.00
IUUC-Dre-027507	Danio rerio	68.94	2.00e-126	445.00
IUUC-Dno-029726	Dasypus novemcinctus	92.77	3.00e-176	611.00
IUUC-Dor-030501	Dipodomys ordii	75.84	2.00e-131	461.00
IUUC-Ete-032794	Echinops telfairi	88.36	2.00e-99	355.00
IUUC-Eca-033982	Equus caballus	95.58	3.00e-172	597.00
IUUC-Eeu-035090	Erinaceus europaeus	80.18	2.00e-101	362.00
IUUC-Fca-035944	Felis catus	97.48	0.00e+00	657.00
IUUC-Fal-036992	Ficedula albicollis	68.77	1.00e-124	439.00
IUUC-Gmo-038710	Gadus morhua	68.35	2.00e-125	442.00
IUUC-Gga-040885	Gallus gallus	76.17	1.00e-89	322.00
IUUC-Gac-041922	Gasterosteus aculeatus	68.85	3.00e-129	454.00
IUUC-Gma-044233	Glycine max	31.19	3.00e-36	145.00
IUUC-Ggo-045172	Gorilla gorilla	91.28	1.00e-171	595.00
IUUC-Hsa-045711	Homo sapiens	91.82	4.00e-171	594.00
IUUC-Itr-048196	Ictidomys tridecemlineatus	90.09	2.00e-168	585.00
IUUC-Lch-049739	Latimeria chalumnae	74.56	2.00e-135	475.00
IUUC-Lpe-050795	Leersia perrieri	27.80	3.00e-22	99.40
IUUC-Loc-052113	Lepisosteus oculatus	78.14	2.00e-133	469.00
IUUC-Laf-053751	Loxodonta africana	91.82	7.00e-178	616.00
IUUC-Mcc-055022	Macaca mulatta	91.82	6.00e-171	593.00
IUUC-Meu-056003	Macropus eugenii	76.84	2.00e-135	475.00
IUUC-Mtr-058500	Medicago truncatula	30.84	1.00e-33	137.00
IUUC-Mga-059278	Meleagris gallopavo	73.68	1.00e-100	359.00
IUUC-Mmr-061148	Microcebus murinus	93.63	5.00e-173	600.00
IUUC-Mdo-063002	Monodelphis domestica	72.56	2.00e-132	465.00
IUUC-Mmu-063607	Mus musculus	90.27	6.00e-166	577.00
IUUC-Mac-065359	Musa acuminata	28.93	1.00e-35	144.00
IUUC-Mlu-067946	Myotis lucifugus	95.28	4.00e-180	624.00
IUUC-Nle-069019	Nomascus leucogenys	92.45	9.00e-173	599.00
IUUC-Opr-071047	Ochotona princeps	91.77	8.00e-169	586.00
IUUC-Ont-071694	Oreochromis niloticus	72.41	5.00e-131	460.00
IUUC-Oan-073474	Ornithorhynchus anatinus	51.27	9.00e-75	273.00
IUUC-Ocu-074493	Oryctolagus cuniculus	90.54	4.00e-162	564.00
IUUC-Oba-075468	Oryza barthii	29.97	2.00e-33	136.00
IUUC-Obr-076681	Oryza brachyantha	29.97	2.00e-34	140.00
IUUC-Ogl-077870	Oryza glaberrima	29.97	2.00e-33	136.00
IUUC-Ogu-078536	Oryza glumaepatula	29.97	2.00e-33	136.00
IUUC-Oin-080175	Oryza indica	29.97	2.00e-33	136.00
IUUC-Olo-080796	Oryza longistaminata	29.65	1.00e-31	130.00
IUUC-Oni-082076	Oryza nivara	29.97	2.00e-33	136.00
IUUC-Opu-083267	Oryza punctata	30.00	5.00e-34	138.00
IUUC-Oru-084553	Oryza rufipogon	29.97	5.00e-33	135.00
IUUC-Osa-085389	Oryza sativa	29.97	2.00e-33	136.00
IUUC-Ola-086414	Oryzias latipes	69.31	2.00e-126	445.00
IUUC-Oga-088656	Otolemur garnettii	91.17	4.00e-169	587.00
IUUC-Oar-089719	Ovis aries	85.43	2.00e-172	598.00
IUUC-Ptr-091087	Pan troglodytes	91.82	7.00e-171	593.00
IUUC-Pan-091709	Papio anubis	92.14	1.00e-171	595.00
IUUC-Psi-093265	Pelodiscus sinensis	69.54	7.00e-143	499.00
IUUC-Pma-094482	Petromyzon marinus	66.21	4.00e-56	209.00
IUUC-Ppa-095365	Physcomitrella patens	29.81	5.00e-36	145.00
IUUC-Pfo-097494	Poecilia formosa	70.69	3.00e-129	454.00
IUUC-Pab-098362	Pongo abelii	91.82	4.00e-171	594.00
IUUC-Pop-099163	Populus trichocarpa	29.91	1.00e-31	130.00
IUUC-Pca-101019	Procavia capensis	91.98	2.00e-118	418.00
IUUC-Ppe-102101	Prunus persica	28.77	3.00e-37	149.00
IUUC-Pva-102849	Pteropus vampyrus	94.65	5.00e-170	590.00
IUUC-Rno-105511	Rattus norvegicus	91.55	4.00e-166	577.00
IUUC-Sha-107265	Sarcophilus harrisii	71.52	2.00e-138	485.00
IUUC-Smo-108980	Selaginella moellendorffii	32.08	5.00e-34	138.00
IUUC-Sit-110806	Setaria italica	30.48	1.00e-33	137.00
IUUC-Sly-110994	Solanum lycopersicum	29.36	2.00e-33	136.00
IUUC-Stu-112493	Solanum tuberosum	35.89	4.00e-30	124.00
IUUC-Sar-113628	Sorex araneus	91.75	2.00e-168	584.00
IUUC-Sbi-114397	Sorghum bicolor	30.03	1.00e-33	137.00
IUUC-Ssc-116418	Sus scrofa	91.33	2.00e-178	618.00
IUUC-Tgu-117054	Taeniopygia guttata	71.28	9.00e-131	459.00
IUUC-Tru-118504	Takifugu rubripes	73.11	5.00e-138	484.00
IUUC-Tni-120254	Tetraodon nigroviridis	72.79	5.00e-136	477.00
IUUC-Tca-121085	Theobroma cacao	30.70	6.00e-37	148.00
IUUC-Tae-124320	Triticum aestivum	32.08	2.00e-36	146.00
IUUC-Tur-126756	Triticum urartu	27.46	1.00e-30	127.00
IUUC-Tbe-127903	Tupaia belangeri	88.96	3.00e-160	558.00
IUUC-Ttr-129118	Tursiops truncatus	93.08	1.00e-180	625.00
IUUC-Vvi-131125	Vitis vinifera	31.13	1.00e-36	147.00
IUUC-Xtr-132287	Xenopus tropicalis	79.44	1.00e-140	493.00
IUUC-Xma-134246	Xiphophorus maculatus	69.66	1.00e-128	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence