iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059619

UUCD1 version

UUC-MeG-00546

Ensembl Protein ID

ENSMGAP00000012674.1

UniProt Accession

G1NHL1; G1NHL1_MELGA

Protein Name

Uncharacterized protein

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000012068.1	ENSMGAT00000013570.1	ENSMGAP00000012674.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-40	133.7	508	540
UBD/Beta-Prp	7.50e-66	222.0	271	564

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d  l++s+s D++++vWD+r
   Q: 508  GHTDNITSLTFsPDsSLIASASMDNSVRVWDIR 540
           8***********999****************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +sp+++lla+g++++++k+w+++++kl                                ++ l gh ++v++++f +d++ l++
   Q: 271  LNTAEISPNSKLLAAGFDNSCVKLWSLRSKKLksephlvdvsrirlacdildeeeeeddsagteMKILRGHCGPVYSTRFLSDSSGLLS 359
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp + +++s+shdrt+r+w  +  + l+ + +gh   v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPCSLYFASASHDRTARLWSFDRTYPLR-IYAGHLLDVDCVKFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v  l+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 448  KTVRLWSTQQGNSVRLFTG-HRGPVLALAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLIASASMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvavlsfg 276
           +Wd+r+  ++    ++ s ++ v + +++
   Q: 536  VWDIRNTYCNAPADGSSSELVGVYTGQMN 564
           ***99999999988888777666663332 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYVDSEGPLK QGLRLCQTAE EMAANLTVQS ESGCANVVSA 60
APCLPEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNMVQN GLKSTVDSFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAACGCG TACGCACAGA GCAGATTCAG ATGGCAGTGT CCTGCTACCT CAAGCGCCGT 60
CAGTATGTGG ACTCAGAAGG TCCCCTAAAA CAAGGGCTGA GGCTGTGTCA GACTGCTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

KEGG

mgp:100541499

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	92.36	0.00e+00	1058.00
IUUC-Apl-003636	Anas platyrhynchos	97.80	0.00e+00	1182.00
IUUC-Aca-004229	Anolis carolinensis	93.21	0.00e+00	1118.00
IUUC-Ame-010599	Astyanax mexicanus	68.21	0.00e+00	840.00
IUUC-Bta-013404	Bos taurus	88.46	0.00e+00	1013.00
IUUC-Cja-019643	Callithrix jacchus	92.53	0.00e+00	1080.00
IUUC-Cfa-020913	Canis familiaris	92.70	0.00e+00	1080.00
IUUC-Cpo-021777	Cavia porcellus	90.49	0.00e+00	1039.00
IUUC-Csa-024184	Chlorocebus sabaeus	92.53	0.00e+00	1082.00
IUUC-Cho-024638	Choloepus hoffmanni	92.70	0.00e+00	1052.00
IUUC-Cin-025618	Ciona intestinalis	34.62	7.00e-88	317.00
IUUC-Csv-025874	Ciona savignyi	33.70	7.00e-89	321.00
IUUC-Dre-028817	Danio rerio	68.44	0.00e+00	826.00
IUUC-Dno-029969	Dasypus novemcinctus	85.74	0.00e+00	1024.00
IUUC-Dor-031117	Dipodomys ordii	90.66	0.00e+00	1064.00
IUUC-Ete-032712	Echinops telfairi	85.74	0.00e+00	958.00
IUUC-Eca-033742	Equus caballus	92.70	0.00e+00	1080.00
IUUC-Eeu-035096	Erinaceus europaeus	90.17	0.00e+00	1082.00
IUUC-Fca-035769	Felis catus	91.71	0.00e+00	1097.00
IUUC-Fal-036645	Ficedula albicollis	97.48	0.00e+00	1112.00
IUUC-Fso-038302	Fusarium solani	33.22	5.00e-39	155.00
IUUC-Gmo-038636	Gadus morhua	65.33	0.00e+00	791.00
IUUC-Gga-040144	Gallus gallus	99.83	0.00e+00	1175.00
IUUC-Gac-041716	Gasterosteus aculeatus	67.73	0.00e+00	820.00
IUUC-Ggo-044568	Gorilla gorilla	92.70	0.00e+00	1082.00
IUUC-Hsa-046178	Homo sapiens	92.70	0.00e+00	1082.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	85.91	0.00e+00	1051.00
IUUC-Lch-050501	Latimeria chalumnae	79.79	0.00e+00	899.00
IUUC-Loc-052895	Lepisosteus oculatus	83.33	0.00e+00	655.00
IUUC-Laf-053950	Loxodonta africana	89.13	0.00e+00	1030.00
IUUC-Mcc-055450	Macaca mulatta	92.53	0.00e+00	1078.00
IUUC-Meu-056182	Macropus eugenii	88.79	0.00e+00	1025.00
IUUC-Mmr-061074	Microcebus murinus	91.20	0.00e+00	1089.00
IUUC-Mdo-062307	Monodelphis domestica	92.92	0.00e+00	896.00
IUUC-Mmu-063226	Mus musculus	89.30	0.00e+00	1034.00
IUUC-Mpu-066016	Mustela putorius furo	92.36	0.00e+00	1056.00
IUUC-Mlu-067257	Myotis lucifugus	84.14	0.00e+00	1041.00
IUUC-Nle-070139	Nomascus leucogenys	92.87	0.00e+00	1083.00
IUUC-Opr-070243	Ochotona princeps	88.79	0.00e+00	1045.00
IUUC-Ont-072686	Oreochromis niloticus	70.17	0.00e+00	850.00
IUUC-Oan-073670	Ornithorhynchus anatinus	83.70	0.00e+00	857.00
IUUC-Ocu-074525	Oryctolagus cuniculus	92.02	0.00e+00	1083.00
IUUC-Ola-086524	Oryzias latipes	68.72	0.00e+00	865.00
IUUC-Oga-088540	Otolemur garnettii	92.87	0.00e+00	1082.00
IUUC-Oar-089793	Ovis aries	86.08	0.00e+00	953.00
IUUC-Ptr-091154	Pan troglodytes	92.70	0.00e+00	1082.00
IUUC-Pan-092759	Papio anubis	92.53	0.00e+00	1078.00
IUUC-Psi-094008	Pelodiscus sinensis	93.21	0.00e+00	1123.00
IUUC-Pma-094593	Petromyzon marinus	46.90	1.00e-136	479.00
IUUC-Pfo-097409	Poecilia formosa	67.72	0.00e+00	823.00
IUUC-Pab-097946	Pongo abelii	82.00	0.00e+00	935.00
IUUC-Pca-100727	Procavia capensis	86.08	0.00e+00	964.00
IUUC-Pva-103211	Pteropus vampyrus	82.34	0.00e+00	987.00
IUUC-Rno-105236	Rattus norvegicus	89.81	0.00e+00	1018.00
IUUC-Sha-106833	Sarcophilus harrisii	93.24	0.00e+00	1096.00
IUUC-Sar-113381	Sorex araneus	92.53	0.00e+00	1109.00
IUUC-Ssc-116421	Sus scrofa	90.32	0.00e+00	1094.00
IUUC-Tgu-117143	Taeniopygia guttata	97.79	0.00e+00	1179.00
IUUC-Tru-118680	Takifugu rubripes	68.50	0.00e+00	847.00
IUUC-Tsy-119622	Tarsius syrichta	77.93	0.00e+00	819.00
IUUC-Tni-120131	Tetraodon nigroviridis	68.17	0.00e+00	849.00
IUUC-Ttr-129171	Tursiops truncatus	89.81	0.00e+00	1032.00
IUUC-Xtr-132241	Xenopus tropicalis	83.56	0.00e+00	991.00
IUUC-Xma-133554	Xiphophorus maculatus	68.60	0.00e+00	763.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence