iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010371.1	ENSOART00000011284.1	ENSOARP00000011124.1
ENSOARG00000010371.1	ENSOART00000011285.1	ENSOARP00000011125.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.10e-15	55.0	374	419
E3 adaptor/Cullin RING/DCX/DWD	1.20e-30	104.4	169	203
UBD/Beta-Prp	1.90e-47	162.1	135	377

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
           +++w ++++++SLqhLCR++Irr +++q++   ++LP P++  ++L+y+
   Q: 374  VYFWATPRQVPSLQHLCRMSIRRVMPTQEV---QELPVPSKVLEFLSYR 419
           689************************999...*************996 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Ht+ v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 169  HTEVVRDLTFaPDgsLILVSASRDKTLRVWDLKDD 203
           9**********8865668*************9987 PP

UBD/Beta-Prp

   S: 17   kfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfs 103
            f +d+ llatg  +g+ik+wdv tgkll  l +h++ v++++f pdg+ ilv++s+D+t++vwdl+ +g ++ +l+gh++ v+s++fs
   Q: 135  RFGQDQLLLATGLNSGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSlILVSASRDKTLRVWDLKdDGNMMKVLRGHQNWVYSCAFS 223
           5678999***********************************************************9799******************* PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl...........tgghtd 181
           p+++ l s ++ + + +w++++++ ++  l+gh++ v    ++pdg ll+++s+D+ v +Wd  tg +l ++            g++++
   Q: 224  PDSSMLCSVGASKAVFLWNMDKYTMIR-KLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHTGAILMEFdlfppptpifaGGANDR 311
           ***************************.9*****************************************************9888*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
            v+s+sf+++g +++s ++ + v++w + +      + +  +n ++ +fs ++  l+ g++Dgs+++W
   Q: 312  WVRSVSFSHDGLHVASLADARMVRFWRIDED--CPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSVYFW 377
           ****************************777..67789999*************************** PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MASFPPRVNE KEIVRSRTIG ELLAPAAPFD KKCGRENWTV AFAPDGSYFA WSQGHRTVKL 60
VAWSQCLKNF LLHGTKNITN SSGLRLSRQN SDGGQKNKPR EHIIDCGDIV WSLAFGSSVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAACTGTT GAACTTTAGA CCTTGTGTGC TAGACTTGTA TTTTTTAAAT TTAAAATTAT 60
AACTTTTTTC GAGTGTCTCG TTTGCTCTCG GAAGTGTGGA AGGAAGTGTC TTCCTTCGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	96.67	0.00e+00	818.00
IUUC-Apl-003903	Anas platyrhynchos	87.96	0.00e+00	757.00
IUUC-Aca-005214	Anolis carolinensis	76.76	0.00e+00	682.00
IUUC-Ame-011740	Astyanax mexicanus	74.58	0.00e+00	666.00
IUUC-Bta-013475	Bos taurus	97.86	0.00e+00	826.00
IUUC-Cja-019053	Callithrix jacchus	95.94	0.00e+00	835.00
IUUC-Cfa-020103	Canis familiaris	97.15	0.00e+00	821.00
IUUC-Cpo-022438	Cavia porcellus	94.06	0.00e+00	825.00
IUUC-Csa-024062	Chlorocebus sabaeus	96.20	0.00e+00	841.00
IUUC-Cho-024334	Choloepus hoffmanni	84.56	0.00e+00	694.00
IUUC-Cin-025590	Ciona intestinalis	38.89	2.00e-73	269.00
IUUC-Csv-026023	Ciona savignyi	40.19	2.00e-75	275.00
IUUC-Dre-028089	Danio rerio	74.35	0.00e+00	667.00
IUUC-Dno-029436	Dasypus novemcinctus	90.08	0.00e+00	653.00
IUUC-Dor-031107	Dipodomys ordii	88.60	0.00e+00	739.00
IUUC-Ete-032326	Echinops telfairi	92.87	0.00e+00	772.00
IUUC-Eca-033401	Equus caballus	96.44	0.00e+00	816.00
IUUC-Eeu-034520	Erinaceus europaeus	93.59	0.00e+00	823.00
IUUC-Fca-036386	Felis catus	97.15	0.00e+00	820.00
IUUC-Fal-036616	Ficedula albicollis	85.01	0.00e+00	731.00
IUUC-Gmo-039335	Gadus morhua	69.73	2.00e-173	601.00
IUUC-Gga-040856	Gallus gallus	86.94	0.00e+00	771.00
IUUC-Gac-042140	Gasterosteus aculeatus	73.24	0.00e+00	652.00
IUUC-Ggo-044619	Gorilla gorilla	95.96	0.00e+00	839.00
IUUC-Hsa-046300	Homo sapiens	95.96	0.00e+00	837.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	94.54	0.00e+00	829.00
IUUC-Lch-049550	Latimeria chalumnae	79.48	4.00e-167	580.00
IUUC-Loc-051769	Lepisosteus oculatus	76.25	0.00e+00	674.00
IUUC-Laf-054576	Loxodonta africana	95.01	0.00e+00	810.00
IUUC-Mcc-054666	Macaca mulatta	96.18	3.00e-149	520.00
IUUC-Meu-055989	Macropus eugenii	88.00	0.00e+00	637.00
IUUC-Mga-059722	Meleagris gallopavo	86.02	0.00e+00	761.00
IUUC-Mmr-060970	Microcebus murinus	95.49	0.00e+00	812.00
IUUC-Mdo-062249	Monodelphis domestica	78.81	0.00e+00	642.00
IUUC-Mmu-063742	Mus musculus	91.67	0.00e+00	806.00
IUUC-Mpu-066518	Mustela putorius furo	97.15	0.00e+00	847.00
IUUC-Mlu-068063	Myotis lucifugus	94.06	0.00e+00	801.00
IUUC-Nle-069561	Nomascus leucogenys	95.72	0.00e+00	838.00
IUUC-Opr-071158	Ochotona princeps	90.71	0.00e+00	792.00
IUUC-Ont-072542	Oreochromis niloticus	72.07	0.00e+00	644.00
IUUC-Oan-073217	Ornithorhynchus anatinus	90.74	0.00e+00	793.00
IUUC-Ocu-074251	Oryctolagus cuniculus	94.62	0.00e+00	791.00
IUUC-Ola-086549	Oryzias latipes	71.13	0.00e+00	645.00
IUUC-Oga-088382	Otolemur garnettii	95.72	0.00e+00	816.00
IUUC-Ptr-090922	Pan troglodytes	95.72	0.00e+00	838.00
IUUC-Pan-092518	Papio anubis	96.20	0.00e+00	841.00
IUUC-Psi-093512	Pelodiscus sinensis	88.12	0.00e+00	778.00
IUUC-Pma-094324	Petromyzon marinus	58.10	1.00e-132	466.00
IUUC-Pfo-096264	Poecilia formosa	71.83	0.00e+00	648.00
IUUC-Pab-098018	Pongo abelii	94.30	0.00e+00	822.00
IUUC-Pca-101034	Procavia capensis	92.87	0.00e+00	756.00
IUUC-Pva-102862	Pteropus vampyrus	91.21	0.00e+00	746.00
IUUC-Rno-106116	Rattus norvegicus	92.40	0.00e+00	812.00
IUUC-Sha-106952	Sarcophilus harrisii	89.49	0.00e+00	741.00
IUUC-Sar-113211	Sorex araneus	83.60	5.00e-145	506.00
IUUC-Ssc-116440	Sus scrofa	97.15	0.00e+00	821.00
IUUC-Tgu-116675	Taeniopygia guttata	85.01	0.00e+00	729.00
IUUC-Tru-118295	Takifugu rubripes	71.36	0.00e+00	625.00
IUUC-Tsy-118916	Tarsius syrichta	83.14	0.00e+00	687.00
IUUC-Tni-120302	Tetraodon nigroviridis	70.66	6.00e-179	620.00
IUUC-Tbe-127416	Tupaia belangeri	82.31	0.00e+00	657.00
IUUC-Ttr-128185	Tursiops truncatus	97.15	0.00e+00	821.00
IUUC-Xtr-132465	Xenopus tropicalis	81.90	0.00e+00	726.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence