iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000000904.8	ENSRNOT00000061252.5	ENSRNOP00000057964.4
ENSRNOG00000000904.8	ENSRNOT00000001203.7	ENSRNOP00000001203.7

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-28	96.9	164	200
UBD/Beta-Prp	1.80e-63	214.9	3	204

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           +++tclaf s+ ++lv+G++Dg +k+W++  g++l++
   Q: 164  AGITCLAFdSSgRRLVTGGRDGDLKIWSYNNGHCLHT 200
           579*****95569*********************986 PP

UBD/Beta-Prp

   S: 64   gkilvtgseDrtikvw.dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.................... 131
           +++l+tg+ Dr+++vw ++  gk++ +l+gh + v+ +++  + +k+ s s+d+t+++wdlet +c  +                    
   Q: 3    KNLLATGGLDRIVRVWnPYLPGKPTGVLRGHMAPVMYVHVASEENKVFSVSADNTVKIWDLETHSCCCTvsskasgikgeltaclylpg 91
           34666666666666664444666666666666666666666666666666666666666666666666666666666666666666666 PP
   S: 132  .........................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkel 195
                                    +l+ h++ v c +++p  + +vs++  ++v++Wdl+tg+ + ++ g  +  +++l+fds+g++l
   Q: 92   pralcvatgtlalfhlkagsvpephLLRSHQEPVVCCRYNPAFRQVVSCCEASVVKVWDLETGRWVSEFIG--NAGITCLAFDSSGRRL 178
           6666666666666666666666679****************88**************************98..999************* PP
   S: 196  vsgsldgtvklwdlqtgecvrtlngh 221
           v+g++dg++k+w++ +g+c++tl+  
   Q: 179  VTGGRDGDLKIWSYNNGHCLHTLQHD 204
           **********************9865 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

RKKNLLATGG LDRIVRVWNP YLPGKPTGVL RGHMAPVMYV HVASEENKVF SVSADNTVKI 60
WDLETHSCCC TVSSKASGIK GELTACLYLP GPRALCVATG TLALFHLKAG SVPEPHLLRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAAGAAAA ACCTGCTGGC GACAGGCGGG CTGGATCGAA TCGTCAGGGT CTGGAATCCT 60
TACCTGCCTG GGTAAGCTGT CTCTCTCCTA CCAAGTGTCC TGCTGCTGTA GCAAAGTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001921	Ailuropoda melanoleuca	70.87	0.00e+00	746.00
IUUC-Ame-011582	Astyanax mexicanus	43.52	1.00e-120	427.00
IUUC-Bta-013034	Bos taurus	65.46	0.00e+00	694.00
IUUC-Cin-025633	Ciona intestinalis	42.26	1.00e-86	313.00
IUUC-Csv-026326	Ciona savignyi	40.35	6.00e-115	407.00
IUUC-Dre-027573	Danio rerio	44.98	3.00e-133	469.00
IUUC-Dno-030073	Dasypus novemcinctus	58.77	0.00e+00	666.00
IUUC-Dme-031984	Drosophila melanogaster	28.64	7.00e-36	146.00
IUUC-Eca-033354	Equus caballus	66.60	0.00e+00	678.00
IUUC-Fca-036185	Felis catus	64.62	0.00e+00	663.00
IUUC-Gmo-039551	Gadus morhua	39.35	2.00e-91	329.00
IUUC-Gac-041482	Gasterosteus aculeatus	45.16	6.00e-125	441.00
IUUC-Itr-049019	Ictidomys tridecemlineatus	71.13	0.00e+00	775.00
IUUC-Lch-050242	Latimeria chalumnae	54.76	4.00e-167	581.00
IUUC-Loc-052710	Lepisosteus oculatus	52.42	6.00e-158	551.00
IUUC-Laf-054508	Loxodonta africana	31.58	4.00e-39	155.00
IUUC-Mcc-054635	Macaca mulatta	30.28	4.00e-40	160.00
IUUC-Mdo-062347	Monodelphis domestica	57.84	0.00e+00	637.00
IUUC-Mmu-063878	Mus musculus	82.62	0.00e+00	1079.00
IUUC-Mpu-065721	Mustela putorius furo	76.33	4.00e-96	343.00
IUUC-Ont-071688	Oreochromis niloticus	43.66	9.00e-121	427.00
IUUC-Oan-072752	Ornithorhynchus anatinus	55.49	9.00e-148	516.00
IUUC-Ocu-074780	Oryctolagus cuniculus	56.23	2.00e-84	305.00
IUUC-Ola-086449	Oryzias latipes	43.29	8.00e-111	394.00
IUUC-Pma-094599	Petromyzon marinus	49.59	2.00e-143	502.00
IUUC-Ppa-095538	Physcomitrella patens	30.77	4.00e-16	80.10
IUUC-Pfo-096408	Poecilia formosa	42.23	1.00e-121	430.00
IUUC-Sha-106832	Sarcophilus harrisii	58.29	0.00e+00	646.00
IUUC-Smo-109247	Selaginella moellendorffii	27.69	9.00e-44	172.00
IUUC-Ssc-116310	Sus scrofa	66.54	0.00e+00	714.00
IUUC-Tru-117666	Takifugu rubripes	44.71	6.00e-123	434.00
IUUC-Tni-120449	Tetraodon nigroviridis	26.39	1.00e-30	127.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence