iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033968

UUCD1 version

UUC-EqC-01062

Ensembl Protein ID

ENSECAP00000015456.1

UniProt Accession

F6R3R6; F6R3R6_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000017723.1	ENSECAT00000018917.1	ENSECAP00000015456.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.80e-70	236.3	42	474

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++  +++ ++ p++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 42   GLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYARDQMEPPPHQYLSLTLLHLLKALScqeVTDDEVLDASCLLDVLRMYRWQISSF 130
           9*****************************777777778889999**************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e+++e          + + +++ ++   ++ F+g+l+s+++c++c+++s +r
   Q: 131  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQSEatpkqitcrtRGSLHPTFTHWKSQHPFHGRLTSNMVCKHCEHQSpVR 217
           *******************9..6688888888888888888877777777777778888888*************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 218  FDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTkieakgtlngekvehQRTTFVKQLKLGKLPQCLCIHLQRLSW 303
           ***********************************97...9******8888888888888777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts............................................................. 267
           s++ + + k +++v+f++ L ++ +  +                                                             
   Q: 304  SSH-GTPLKRHEHVQFNEFLMMDIYKYHllghkpgqrgpklkenpgpvvelqdgpaaprsvlnqpggpktqifmngacspsllptlptp 391
           998.8888*********888888666666678888877777777777777666666666666666665555555555555555555555 PP
   S: 268  ........peekqke....kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
                   p     +    ++ ++L+avvvH+G ++sGH+v+y ++         ++ +Wl ++D++V++ + +evl+   s+aY+lfY
   Q: 392  mpfplpvvP-----DysssSYLFRLMAVVVHHGDMHSGHFVTYRRSppsaknplsTSSQWLWISDDSVRKASLQEVLS---SSAYLLFY 472
           555555553.....055559**************************9988888877888*******************...******** PP
   S: 336  kr 337
           +r
   Q: 473  ER 474
           98 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

RYKVMKNWGV IGGIAAALAA GIYVIWGPIT ERKKRRKGLV PGLVNLGNTC FMNSLLQGLS 60
ACPAFIRWLE EFTSQYARDQ MEPPPHQYLS LTLLHLLKAL SCQEVTDDEV LDASCLLDVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTTTAGAT ATAAAGTCAT GAAGAACTGG GGTGTTATAG GTGGAATTGC GGCTGCTCTT 60
GCAGCAGGAA TATATGTTAT TTGGGGTCCC ATTACGGAAA GAAAGAAGCG TAGAAAAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	26.56	3.00e-17	82.80
IUUC-Aml-001733	Ailuropoda melanoleuca	92.09	0.00e+00	828.00
IUUC-Atr-002510	Amborella trichopoda	24.66	6.00e-21	95.50
IUUC-Apl-003645	Anas platyrhynchos	72.56	1.00e-106	379.00
IUUC-Aca-004583	Anolis carolinensis	69.74	2.00e-24	103.00
IUUC-Aly-005754	Arabidopsis lyrata	26.25	2.00e-25	110.00
IUUC-Ath-007622	Arabidopsis thaliana	26.34	1.00e-24	107.00
IUUC-Ani-009286	Aspergillus nidulans	20.98	7.00e-12	65.50
IUUC-Ame-010896	Astyanax mexicanus	62.45	3.00e-155	541.00
IUUC-Bta-012321	Bos taurus	91.43	0.00e+00	830.00
IUUC-Bdi-014795	Brachypodium distachyon	26.95	5.00e-17	82.00
IUUC-Bol-015637	Brassica oleracea	26.27	2.00e-23	103.00
IUUC-Bra-016801	Brassica rapa	26.30	2.00e-24	107.00
IUUC-Cel-018308	Caenorhabditis elegans	27.68	4.00e-35	142.00
IUUC-Cja-018826	Callithrix jacchus	93.28	0.00e+00	889.00
IUUC-Cfa-021206	Canis familiaris	92.29	0.00e+00	835.00
IUUC-Cpo-021343	Cavia porcellus	92.04	0.00e+00	823.00
IUUC-Csa-023419	Chlorocebus sabaeus	93.88	0.00e+00	893.00
IUUC-Cho-024475	Choloepus hoffmanni	90.11	1.00e-136	479.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.46	1.00e-12	68.20
IUUC-Cne-027061	Cryptococcus neoformans	25.00	4.00e-10	60.10
IUUC-Dre-027563	Danio rerio	58.79	1.00e-153	536.00
IUUC-Dno-029929	Dasypus novemcinctus	91.84	0.00e+00	843.00
IUUC-Dor-030166	Dipodomys ordii	81.63	0.00e+00	713.00
IUUC-Dme-031627	Drosophila melanogaster	33.57	3.00e-34	139.00
IUUC-Ete-032634	Echinops telfairi	81.43	0.00e+00	682.00
IUUC-Eeu-035279	Erinaceus europaeus	82.32	9.00e-59	221.00
IUUC-Fca-036525	Felis catus	93.27	0.00e+00	862.00
IUUC-Fal-036606	Ficedula albicollis	74.35	2.00e-159	555.00
IUUC-Gmo-038726	Gadus morhua	58.69	3.00e-140	491.00
IUUC-Gga-040718	Gallus gallus	75.69	2.00e-162	565.00
IUUC-Gac-042645	Gasterosteus aculeatus	59.14	3.00e-148	518.00
IUUC-Gma-042890	Glycine max	26.45	9.00e-26	111.00
IUUC-Ggo-045021	Gorilla gorilla	94.08	0.00e+00	892.00
IUUC-Hsa-045832	Homo sapiens	94.08	0.00e+00	892.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	93.67	0.00e+00	845.00
IUUC-Lch-050662	Latimeria chalumnae	70.76	6.00e-179	620.00
IUUC-Lpe-051078	Leersia perrieri	25.92	6.00e-30	125.00
IUUC-Loc-052611	Lepisosteus oculatus	66.87	4.00e-174	604.00
IUUC-Lma-053048	Leptosphaeria maculans	20.20	5.00e-15	76.60
IUUC-Laf-053752	Loxodonta africana	92.86	0.00e+00	832.00
IUUC-Mcc-054892	Macaca mulatta	94.29	0.00e+00	896.00
IUUC-Meu-056673	Macropus eugenii	74.67	2.00e-161	561.00
IUUC-Mor-057143	Magnaporthe oryzae	21.95	9.00e-09	55.50
IUUC-Mtr-057976	Medicago truncatula	26.14	2.00e-34	140.00
IUUC-Mga-059543	Meleagris gallopavo	76.82	0.00e+00	664.00
IUUC-Mmr-061534	Microcebus murinus	93.06	0.00e+00	859.00
IUUC-Mdo-062140	Monodelphis domestica	69.96	1.00e-166	579.00
IUUC-Mmu-063673	Mus musculus	89.59	0.00e+00	807.00
IUUC-Mpu-066328	Mustela putorius furo	91.63	0.00e+00	831.00
IUUC-Mlu-067938	Myotis lucifugus	93.47	0.00e+00	858.00
IUUC-Nle-069426	Nomascus leucogenys	93.21	0.00e+00	822.00
IUUC-Opr-070796	Ochotona princeps	87.16	1.00e-124	439.00
IUUC-Ont-072248	Oreochromis niloticus	61.05	8.00e-155	540.00
IUUC-Oan-072916	Ornithorhynchus anatinus	81.43	0.00e+00	754.00
IUUC-Ocu-074459	Oryctolagus cuniculus	86.67	0.00e+00	661.00
IUUC-Oba-075765	Oryza barthii	25.88	2.00e-28	120.00
IUUC-Obr-076005	Oryza brachyantha	27.07	2.00e-30	126.00
IUUC-Ogl-077916	Oryza glaberrima	26.18	1.00e-31	131.00
IUUC-Ogu-078263	Oryza glumaepatula	26.12	3.00e-29	123.00
IUUC-Oin-080096	Oryza indica	26.19	1.00e-22	100.00
IUUC-Ome-081928	Oryza meridionalis	26.13	1.00e-29	124.00
IUUC-Oni-082424	Oryza nivara	26.12	2.00e-29	123.00
IUUC-Oru-085117	Oryza rufipogon	26.12	2.00e-29	123.00
IUUC-Ola-087429	Oryzias latipes	58.39	1.00e-142	499.00
IUUC-Oga-087981	Otolemur garnettii	92.65	0.00e+00	847.00
IUUC-Oar-089927	Ovis aries	91.22	0.00e+00	829.00
IUUC-Ptr-090878	Pan troglodytes	94.08	0.00e+00	892.00
IUUC-Pan-092698	Papio anubis	94.29	0.00e+00	896.00
IUUC-Psi-093451	Pelodiscus sinensis	77.03	0.00e+00	714.00
IUUC-Ppa-096015	Physcomitrella patens	23.67	1.00e-13	71.60
IUUC-Pfo-096096	Poecilia formosa	61.04	3.00e-151	528.00
IUUC-Pab-098676	Pongo abelii	92.86	0.00e+00	870.00
IUUC-Pca-100418	Procavia capensis	94.64	1.00e-126	446.00
IUUC-Ppe-101898	Prunus persica	24.37	1.00e-23	104.00
IUUC-Pva-103018	Pteropus vampyrus	91.02	0.00e+00	819.00
IUUC-Pgr-103423	Puccinia graminis	26.00	3.00e-10	60.80
IUUC-Pte-104330	Pyrenophora teres	22.18	6.00e-15	75.90
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.66	1.00e-16	81.60
IUUC-Rno-105708	Rattus norvegicus	88.57	0.00e+00	797.00
IUUC-Sha-106971	Sarcophilus harrisii	82.79	0.00e+00	769.00
IUUC-Sit-110442	Setaria italica	28.18	1.00e-28	120.00
IUUC-Stu-112223	Solanum tuberosum	24.50	6.00e-16	78.60
IUUC-Ssc-116397	Sus scrofa	90.82	0.00e+00	827.00
IUUC-Tgu-117446	Taeniopygia guttata	70.19	0.00e+00	638.00
IUUC-Tru-118268	Takifugu rubripes	59.67	9.00e-139	486.00
IUUC-Tsy-119484	Tarsius syrichta	86.61	2.00e-49	190.00
IUUC-Tni-119735	Tetraodon nigroviridis	57.81	4.00e-122	431.00
IUUC-Tca-121660	Theobroma cacao	24.77	4.00e-27	116.00
IUUC-Tae-125383	Triticum aestivum	27.37	4.00e-27	115.00
IUUC-Tur-126458	Triticum urartu	27.62	1.00e-25	110.00
IUUC-Tbe-127740	Tupaia belangeri	85.92	0.00e+00	754.00
IUUC-Ttr-129273	Tursiops truncatus	89.39	0.00e+00	801.00
IUUC-Vvi-131177	Vitis vinifera	26.68	2.00e-25	110.00
IUUC-Xtr-132374	Xenopus tropicalis	68.06	1.00e-170	592.00
IUUC-Xma-133267	Xiphophorus maculatus	62.13	1.00e-152	533.00
IUUC-Yli-134571	Yarrowia lipolytica	23.81	4.00e-12	66.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence