iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072916

UUCD1 version

UUC-OrA-00858

Ensembl Protein ID

ENSOANP00000014025.1

UniProt Accession

F7G2Z6; F7G2Z6_ORNAN

Protein Name

Uncharacterized protein

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000008802.1	ENSOANT00000014028.1	ENSOANP00000014025.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-67	227.9	66	491

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l + + +   ++++++++  l+ +l +l+++l      ++ + + + ll++l+ +  ++s++
   Q: 66   GLLNLGNTCFMNSLLQGLSACPAFIKWLEDFTAQYSTDQKETSTDRYLSLTLLRLLKALScqdVMNDDVLDASCLLEVLRLYRWQISSF 154
           9*****************************5555566666789999*************8888888899******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e++ e          +   ++  ++   ++ F+g+l+s+++c++c+++s +r
   Q: 155  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDIQSLEQQPEiipqqvtcrtRGTPHPLPSHWNSQHPFHGRLTSNMVCKHCERQSpVR 241
           *******************9..6799999999999888888899999999988899999999*************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +   + +l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 242  YDTFDSLSLSIPAATWGRPVTLDHCLHHFISSESVRD---VVCDNCTkieaegtlngemvenQRTTFVKQLKLGKLPQCLCIHLQRLSW 327
           ***********************************97...9******8888888888888877777*********************** PP
   S: 240  seeqksrekinkkvefpleLdls..pfcts......peekqke.............................................. 274
           s++ + + k +++v+f++ L ++  ++               +                                              
   Q: 328  SNH-GTPLKRHEHVQFNEFLIMDiyKYHLPghkasqH-----Npkkkdpalemktaaaikraavdqpggpktlvmngacspallpspit 410
           998.8888*********88655522555445444440.....14555666677777777777777777777777777777777777777 PP
   S: 275  ............kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                       ++ ++L+avvvH+G ++sGH+v+y ++          + +Wl ++D++V++ + +evl+   s+aY+lfY+r
   Q: 411  lslpvipdysssSYLFRLMAVVVHHGDMHSGHFVTYRRSpppaksprsASSQWLWISDDTVRKASLQEVLS---SSAYLLFYER 491
           77777777777799*************************9998888777888*******************...********98 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

RRARPAAMLS PRGLRRLLRT GAAVRYKVMK NWGVLGGIAA ALVAGIYVLW GPITERKKRR 60
KGLVPGLLNL GNTCFMNSLL QGLSACPAFI KWLEDFTAQY STDQKETSTD RYLSLTLLRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCGGGCGA GGCCGGCGGC CATGCTGAGC CCTCGGGGCC TCCGGAGGCT GCTGAGGACC 60
GGAGCCGCCG TCAGGTCAGT CGGCCGGAGC CCTCCCGACT CACAGACCAC GGCTCACCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	26.36	1.00e-16	80.90
IUUC-Aml-001733	Ailuropoda melanoleuca	79.96	0.00e+00	763.00
IUUC-Atr-002510	Amborella trichopoda	25.67	8.00e-24	104.00
IUUC-Apl-003645	Anas platyrhynchos	74.36	7.00e-113	399.00
IUUC-Aca-004583	Anolis carolinensis	68.42	2.00e-24	102.00
IUUC-Aly-005754	Arabidopsis lyrata	26.37	2.00e-24	106.00
IUUC-Ath-007622	Arabidopsis thaliana	28.11	1.00e-25	110.00
IUUC-Acl-008136	Aspergillus clavatus	22.25	8.00e-12	65.10
IUUC-Afl-008530	Aspergillus flavus	22.77	4.00e-11	62.80
IUUC-Afu-009119	Aspergillus fumigatus	21.93	8.00e-10	58.50
IUUC-Aor-009934	Aspergillus oryzae	22.94	5.00e-11	62.00
IUUC-Ate-010439	Aspergillus terreus	23.28	1.00e-12	67.80
IUUC-Ame-010896	Astyanax mexicanus	62.92	3.00e-163	567.00
IUUC-Bgr-012133	Blumeria graminis	22.87	5.00e-13	69.30
IUUC-Bta-012321	Bos taurus	80.44	0.00e+00	768.00
IUUC-Bci-013590	Botrytis cinerea	21.85	8.00e-13	68.60
IUUC-Bdi-014795	Brachypodium distachyon	27.01	1.00e-16	80.50
IUUC-Bol-015637	Brassica oleracea	26.89	1.00e-23	103.00
IUUC-Bra-016801	Brassica rapa	25.11	8.00e-24	104.00
IUUC-Cel-018308	Caenorhabditis elegans	26.92	2.00e-36	145.00
IUUC-Cja-018826	Callithrix jacchus	81.08	0.00e+00	801.00
IUUC-Cfa-021206	Canis familiaris	78.68	0.00e+00	764.00
IUUC-Cpo-021343	Cavia porcellus	79.04	0.00e+00	757.00
IUUC-Csa-023419	Chlorocebus sabaeus	80.84	0.00e+00	796.00
IUUC-Cho-024475	Choloepus hoffmanni	78.91	3.00e-121	427.00
IUUC-Cne-027061	Cryptococcus neoformans	26.00	6.00e-09	55.50
IUUC-Dre-027563	Danio rerio	62.40	2.00e-167	581.00
IUUC-Dno-029929	Dasypus novemcinctus	80.08	0.00e+00	780.00
IUUC-Dor-030166	Dipodomys ordii	72.06	0.00e+00	654.00
IUUC-Dme-031627	Drosophila melanogaster	35.16	1.00e-35	143.00
IUUC-Ete-032634	Echinops telfairi	74.19	0.00e+00	644.00
IUUC-Eca-033968	Equus caballus	80.82	0.00e+00	746.00
IUUC-Eeu-035279	Erinaceus europaeus	75.61	1.00e-53	203.00
IUUC-Fca-036525	Felis catus	80.84	0.00e+00	792.00
IUUC-Fal-036606	Ficedula albicollis	73.68	5.00e-162	563.00
IUUC-Fox-037837	Fusarium oxysporum	22.30	2.00e-11	63.50
IUUC-Gmo-038726	Gadus morhua	57.68	2.00e-147	514.00
IUUC-Gga-040718	Gallus gallus	74.68	4.00e-166	576.00
IUUC-Gac-042645	Gasterosteus aculeatus	60.49	1.00e-156	545.00
IUUC-Gma-042890	Glycine max	24.86	4.00e-23	102.00
IUUC-Ggo-045021	Gorilla gorilla	81.24	0.00e+00	796.00
IUUC-Hsa-045832	Homo sapiens	81.24	0.00e+00	796.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	81.22	0.00e+00	754.00
IUUC-Lch-050662	Latimeria chalumnae	72.65	0.00e+00	631.00
IUUC-Lpe-051078	Leersia perrieri	26.01	1.00e-28	120.00
IUUC-Loc-052611	Lepisosteus oculatus	66.00	0.00e+00	627.00
IUUC-Lma-053048	Leptosphaeria maculans	20.61	1.00e-13	70.90
IUUC-Laf-053752	Loxodonta africana	81.43	0.00e+00	743.00
IUUC-Mcc-054892	Macaca mulatta	81.24	0.00e+00	799.00
IUUC-Meu-056673	Macropus eugenii	74.21	1.00e-162	565.00
IUUC-Mor-057143	Magnaporthe oryzae	21.00	1.00e-11	64.70
IUUC-Mtr-057976	Medicago truncatula	25.67	2.00e-31	130.00
IUUC-Mla-058970	Melampsora laricipopulina	23.66	1.00e-19	90.50
IUUC-Mga-059543	Meleagris gallopavo	75.06	0.00e+00	669.00
IUUC-Mmr-061534	Microcebus murinus	81.24	0.00e+00	782.00
IUUC-Mdo-062140	Monodelphis domestica	69.78	4.00e-169	587.00
IUUC-Mmu-063673	Mus musculus	79.44	0.00e+00	746.00
IUUC-Mpu-066328	Mustela putorius furo	79.72	0.00e+00	760.00
IUUC-Mlu-067938	Myotis lucifugus	80.31	0.00e+00	797.00
IUUC-Nfi-068306	Neosartorya fischeri	22.76	8.00e-11	61.20
IUUC-Nle-069426	Nomascus leucogenys	79.86	0.00e+00	711.00
IUUC-Opr-070796	Ochotona princeps	73.15	7.00e-105	373.00
IUUC-Ont-072248	Oreochromis niloticus	60.95	9.00e-162	562.00
IUUC-Ocu-074459	Oryctolagus cuniculus	76.41	2.00e-172	597.00
IUUC-Oba-075765	Oryza barthii	27.45	6.00e-28	118.00
IUUC-Obr-076005	Oryza brachyantha	26.38	2.00e-28	119.00
IUUC-Ogl-077916	Oryza glaberrima	28.24	1.00e-30	127.00
IUUC-Ogu-078263	Oryza glumaepatula	27.64	2.00e-29	123.00
IUUC-Oin-080096	Oryza indica	27.83	1.00e-22	100.00
IUUC-Ome-081928	Oryza meridionalis	26.68	1.00e-29	123.00
IUUC-Oni-082424	Oryza nivara	27.45	8.00e-29	121.00
IUUC-Oru-085117	Oryza rufipogon	27.45	8.00e-29	121.00
IUUC-Ola-087429	Oryzias latipes	58.87	2.00e-150	525.00
IUUC-Oga-087981	Otolemur garnettii	81.04	0.00e+00	775.00
IUUC-Oar-089927	Ovis aries	80.24	0.00e+00	765.00
IUUC-Ptr-090878	Pan troglodytes	81.24	0.00e+00	796.00
IUUC-Pan-092698	Papio anubis	81.24	0.00e+00	799.00
IUUC-Psi-093451	Pelodiscus sinensis	77.51	0.00e+00	728.00
IUUC-Pno-094802	Phaeosphaeria nodorum	21.58	4.00e-11	62.40
IUUC-Ppa-096015	Physcomitrella patens	24.50	6.00e-13	68.90
IUUC-Pfo-096096	Poecilia formosa	61.70	2.00e-158	551.00
IUUC-Pab-098676	Pongo abelii	80.24	0.00e+00	777.00
IUUC-Pca-100418	Procavia capensis	85.06	2.00e-118	418.00
IUUC-Ppe-101898	Prunus persica	24.04	1.00e-24	107.00
IUUC-Pva-103018	Pteropus vampyrus	77.97	0.00e+00	749.00
IUUC-Pgr-103423	Puccinia graminis	25.52	4.00e-10	60.10
IUUC-Pte-104330	Pyrenophora teres	21.61	3.00e-16	79.70
IUUC-Pyt-104518	Pyrenophora triticirepentis	22.18	2.00e-18	87.40
IUUC-Rno-105708	Rattus norvegicus	78.64	0.00e+00	739.00
IUUC-Sha-106971	Sarcophilus harrisii	80.72	0.00e+00	769.00
IUUC-Smo-109086	Selaginella moellendorffii	22.80	3.00e-14	72.00
IUUC-Sit-110442	Setaria italica	27.15	2.00e-25	109.00
IUUC-Stu-112223	Solanum tuberosum	25.21	3.00e-16	79.00
IUUC-Ssc-116397	Sus scrofa	80.04	0.00e+00	760.00
IUUC-Tgu-117446	Taeniopygia guttata	69.42	0.00e+00	651.00
IUUC-Tru-118268	Takifugu rubripes	58.70	4.00e-146	510.00
IUUC-Tsy-119484	Tarsius syrichta	73.23	2.00e-43	169.00
IUUC-Tni-119735	Tetraodon nigroviridis	56.56	2.00e-124	438.00
IUUC-Tca-121660	Theobroma cacao	25.80	1.00e-28	120.00
IUUC-Tae-125203	Triticum aestivum	27.85	3.00e-26	112.00
IUUC-Tur-126458	Triticum urartu	26.98	6.00e-24	104.00
IUUC-Tbe-127740	Tupaia belangeri	75.25	0.00e+00	697.00
IUUC-Ttr-129273	Tursiops truncatus	78.24	0.00e+00	737.00
IUUC-Vda-129757	Verticillium dahliae	21.01	5.00e-09	55.80
IUUC-Vvi-131177	Vitis vinifera	25.91	6.00e-26	111.00
IUUC-Xtr-132374	Xenopus tropicalis	66.46	1.00e-174	605.00
IUUC-Xma-133267	Xiphophorus maculatus	62.08	2.00e-160	558.00
IUUC-Yli-134571	Yarrowia lipolytica	24.72	1.00e-12	67.40
IUUC-Zma-135796	Zea mays	27.58	6.00e-26	111.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence