iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069618

Ensembl Protein ID

ENSNLEP00000002708.1

UniProt Accession

G1QP42; G1QP42_NOMLE

Genbank Protein ID

ENSNLEP00000002708

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01101999

Gene Name

EML2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000002246.2	ENSNLET00000002854.2	ENSNLEP00000002708.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-13	48.2	418	447

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtcla.fsd.tllvsGsdDgtikvWD 29
           H ++v++l+ + d tl++ G++D  + +W 
   Q: 418  HDGGVFGLCaLRDgTLVSGGGRDRRVVLWG 447
           999****97367746655588********6 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

DDNLSGTSGM EVDDRVSALE QRLQLQEDEL AVLKAALADA LRRLRACEEQ GAALRARGTP 60
KGRAPPRLGT TASVCQLLKG LPTRTPLNGS GPPRRVGGYA TSPSSPKKEA TSGRSSVRRY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGACAATT TATCGGGCAC GAGCGGTATG GAAGTGGACG ACCGCGTGTC GGCGCTGGAG 60
CAGCGGCTGC AGTTACAGGA AGACGAGTTG GCGGTCCTAA AGGCGGCGCT GGCGGATGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005108--HELP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0072686--C:mitotic spindle
GO:0031115--P:negative regulation of microtubule polymerization
GO:0010968--P:regulation of microtubule nucleation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	87.95	0.00e+00	1305.00
IUUC-Aca-005316	Anolis carolinensis	68.96	0.00e+00	996.00
IUUC-Bta-013267	Bos taurus	87.59	0.00e+00	1303.00
IUUC-Cja-019146	Callithrix jacchus	82.53	0.00e+00	1071.00
IUUC-Cfa-020267	Canis familiaris	88.46	0.00e+00	1319.00
IUUC-Dno-028961	Dasypus novemcinctus	86.65	0.00e+00	1276.00
IUUC-Eca-033785	Equus caballus	86.67	0.00e+00	1277.00
IUUC-Eeu-035302	Erinaceus europaeus	95.11	0.00e+00	723.00
IUUC-Fca-036170	Felis catus	84.80	0.00e+00	1256.00
IUUC-Ggo-044669	Gorilla gorilla	86.61	0.00e+00	1284.00
IUUC-Hsa-046141	Homo sapiens	90.44	0.00e+00	1350.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	86.98	0.00e+00	1293.00
IUUC-Laf-054137	Loxodonta africana	81.30	0.00e+00	1010.00
IUUC-Mcc-055780	Macaca mulatta	86.66	0.00e+00	1045.00
IUUC-Meu-056664	Macropus eugenii	73.80	0.00e+00	954.00
IUUC-Mmr-060853	Microcebus murinus	87.67	0.00e+00	1308.00
IUUC-Mdo-062224	Monodelphis domestica	77.53	0.00e+00	993.00
IUUC-Mmu-063860	Mus musculus	87.28	0.00e+00	1298.00
IUUC-Mpu-066043	Mustela putorius furo	88.04	0.00e+00	1309.00
IUUC-Mlu-067125	Myotis lucifugus	70.94	0.00e+00	938.00
IUUC-Opr-070228	Ochotona princeps	76.43	0.00e+00	959.00
IUUC-Ocu-074087	Oryctolagus cuniculus	74.13	0.00e+00	734.00
IUUC-Oga-088048	Otolemur garnettii	87.23	0.00e+00	1298.00
IUUC-Oar-089907	Ovis aries	84.90	0.00e+00	1069.00
IUUC-Pan-092082	Papio anubis	89.84	0.00e+00	1336.00
IUUC-Pab-097619	Pongo abelii	87.69	0.00e+00	1137.00
IUUC-Pca-101070	Procavia capensis	74.73	0.00e+00	929.00
IUUC-Rno-105074	Rattus norvegicus	83.51	0.00e+00	1067.00
IUUC-Sha-106692	Sarcophilus harrisii	74.14	0.00e+00	1066.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence