• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Bta-012602
Ensembl Protein ID ENSBTAP00000022552.4
UniProt Accession Q2KIY3; WDFY1_BOVIN
Genbank Protein ID AAI12464.1
Protein Name WD repeat and FYVE domain-containing protein 1; WD40- and FYVE domain-containing protein 1
Genbank Nucleotide ID BC112463
Gene Name WDFY1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000016951.4 ENSBTAT00000022552.4 ENSBTAP00000022552.4
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.40e-18 65.7 240 271
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH d+v +l++   ++ lvs+s Dg i vW++
   Q: 240  GHHDRVQALCYlqLTRQLVSCSSDGGIAVWNM 271
           79999****99884489*************97 PP
   
Organism Bos taurus
Functional Description
(View)

Functional Description


     Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines.
 Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines.
Protein Sequence
(Fasta)
MAAEIHSRPQ SSRPVLLSKI EGHQDAVTAA LLIPKEDGVI TASEDRTIRV WLKRDSGQYW 60
PSIYHTMASP CSAMAYHHDS RRIFVGQDNG AVMEFHVSED FNKMNFIKTY PAHQNRVTAI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-012602|E3,WD_repeat|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCAGTCAGCT GATGGGCCGC CCGTCGCGGA GACCGCCGCC GCCGCTCGAA CATGGCGGCC 60
GAGATCCACT CCAGGCCGCA GAGCAGCCGC CCGGTGCTGC TGAGCAAGAT AGAGGGGCAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-012602|E3,WD_repeat|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0967--Endosome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50178--ZF_FYVE
Pfam

PF01363--FYVE
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00064--FYVE
SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005634--C:nucleus
GO:0005545--F:1-phosphatidylinositol binding
GO:0046872--F:metal ion binding
GO:0034141--P:positive regulation of toll-like receptor 3 signaling pathway
GO:0034145--P:positive regulation of toll-like receptor 4 signaling pathway
KEGG bta:614729
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001526 Ailuropoda melanoleuca 95.53 0.00e+00 814.00
IUUC-Apl-003661 Anas platyrhynchos 90.44 0.00e+00 724.00
IUUC-Aca-005225 Anolis carolinensis 90.20 0.00e+00 781.00
IUUC-Ame-011044 Astyanax mexicanus 77.02 0.00e+00 663.00
IUUC-Cel-018382 Caenorhabditis elegans 38.61 2.00e-94 338.00
IUUC-Cja-019529 Callithrix jacchus 97.07 0.00e+00 847.00
IUUC-Cfa-020512 Canis familiaris 96.45 0.00e+00 748.00
IUUC-Cpo-022239 Cavia porcellus 94.39 0.00e+00 820.00
IUUC-Csa-023535 Chlorocebus sabaeus 96.51 0.00e+00 708.00
IUUC-Cho-024858 Choloepus hoffmanni 79.27 0.00e+00 653.00
IUUC-Cin-025573 Ciona intestinalis 50.50 2.00e-125 442.00
IUUC-Csv-026091 Ciona savignyi 50.75 1.00e-125 442.00
IUUC-Dre-028520 Danio rerio 79.90 0.00e+00 686.00
IUUC-Dno-030005 Dasypus novemcinctus 97.56 0.00e+00 846.00
IUUC-Dor-030500 Dipodomys ordii 95.64 3.00e-176 610.00
IUUC-Dme-031869 Drosophila melanogaster 47.78 5.00e-121 427.00
IUUC-Ete-032870 Echinops telfairi 81.17 4.00e-148 516.00
IUUC-Eca-033284 Equus caballus 94.65 0.00e+00 810.00
IUUC-Eeu-034637 Erinaceus europaeus 56.14 2.00e-142 498.00
IUUC-Fca-036212 Felis catus 96.98 0.00e+00 753.00
IUUC-Fal-037595 Ficedula albicollis 90.69 0.00e+00 806.00
IUUC-Gmo-038664 Gadus morhua 82.06 0.00e+00 732.00
IUUC-Gga-040400 Gallus gallus 90.93 0.00e+00 806.00
IUUC-Gac-041434 Gasterosteus aculeatus 82.35 0.00e+00 736.00
IUUC-Ggo-044590 Gorilla gorilla 62.91 3.00e-164 570.00
IUUC-Hsa-045884 Homo sapiens 97.80 0.00e+00 851.00
IUUC-Itr-048815 Ictidomys tridecemlineatus 97.48 0.00e+00 661.00
IUUC-Lch-049995 Latimeria chalumnae 86.59 0.00e+00 773.00
IUUC-Loc-052075 Lepisosteus oculatus 85.19 0.00e+00 751.00
IUUC-Laf-054345 Loxodonta africana 96.59 0.00e+00 843.00
IUUC-Mcc-055293 Macaca mulatta 96.83 0.00e+00 840.00
IUUC-Meu-056323 Macropus eugenii 62.92 2.00e-159 554.00
IUUC-Mga-059585 Meleagris gallopavo 89.59 0.00e+00 721.00
IUUC-Mmr-061268 Microcebus murinus 97.80 0.00e+00 850.00
IUUC-Mdo-061857 Monodelphis domestica 92.40 0.00e+00 812.00
IUUC-Mmu-063789 Mus musculus 98.05 0.00e+00 848.00
IUUC-Mpu-066391 Mustela putorius furo 97.56 0.00e+00 846.00
IUUC-Mlu-067636 Myotis lucifugus 96.44 0.00e+00 751.00
IUUC-Nle-068974 Nomascus leucogenys 97.56 0.00e+00 847.00
IUUC-Opr-070553 Ochotona princeps 84.63 0.00e+00 707.00
IUUC-Ont-072372 Oreochromis niloticus 63.91 4.00e-164 570.00
IUUC-Oan-073659 Ornithorhynchus anatinus 92.69 0.00e+00 686.00
IUUC-Ocu-074034 Oryctolagus cuniculus 97.80 0.00e+00 847.00
IUUC-Ola-087030 Oryzias latipes 82.11 0.00e+00 738.00
IUUC-Oga-087962 Otolemur garnettii 96.99 0.00e+00 757.00
IUUC-Oar-089377 Ovis aries 100.00 0.00e+00 859.00
IUUC-Ptr-090728 Pan troglodytes 97.32 0.00e+00 848.00
IUUC-Pan-092130 Papio anubis 96.59 0.00e+00 839.00
IUUC-Psi-093886 Pelodiscus sinensis 90.63 0.00e+00 724.00
IUUC-Pfo-097254 Poecilia formosa 83.17 0.00e+00 743.00
IUUC-Pab-097594 Pongo abelii 97.56 0.00e+00 849.00
IUUC-Pca-100741 Procavia capensis 86.81 0.00e+00 654.00
IUUC-Pva-102441 Pteropus vampyrus 94.78 0.00e+00 698.00
IUUC-Rno-105767 Rattus norvegicus 96.83 0.00e+00 844.00
IUUC-Sha-106731 Sarcophilus harrisii 92.29 0.00e+00 726.00
IUUC-Sar-113400 Sorex araneus 50.19 5.00e-75 273.00
IUUC-Ssc-115316 Sus scrofa 98.10 4.00e-125 440.00
IUUC-Tgu-116691 Taeniopygia guttata 90.69 0.00e+00 805.00
IUUC-Tru-118169 Takifugu rubripes 83.09 0.00e+00 739.00
IUUC-Tsy-119047 Tarsius syrichta 84.07 0.00e+00 629.00
IUUC-Tni-120708 Tetraodon nigroviridis 82.89 0.00e+00 736.00
IUUC-Tbe-127442 Tupaia belangeri 97.25 0.00e+00 756.00
IUUC-Ttr-128779 Tursiops truncatus 86.83 0.00e+00 733.00
IUUC-Vpa-130488 Vicugna pacos 94.23 5.00e-120 422.00
IUUC-Xtr-131994 Xenopus tropicalis 81.42 0.00e+00 727.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved