iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033360

UUCD1 version

UUC-EqC-00627

Ensembl Protein ID

ENSECAP00000016448.1

UniProt Accession

F7A4K0; F7A4K0_HORSE

Protein Name

Uncharacterized protein

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018629.1	ENSECAT00000020055.1	ENSECAP00000016448.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-16	59.6	124	158

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H d v+ ++  s+ t  vsGs D  ikvWDl ++ 
   Q: 124  HDDVVSTVSVlSSgTQAVSGSKDFCIKVWDLAQQM 158
           99999***977555****************98765 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MREETSSPLG APAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG DRGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCTGAGGC CCAGCGGGGC ACCACGTGGG CCTTGCTATC CAGAGCTGAA TCTCCCGCTG 60
GTGTCCAGTT TGGGTCTGGG TTGGAGTTGG GACTGTGGAG ATGCGGGAGG AAACCTCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

KEGG

ecb:100058858

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	92.42	6.00e-174	603.00
IUUC-Apl-003921	Anas platyrhynchos	63.16	2.00e-66	244.00
IUUC-Aca-004870	Anolis carolinensis	70.61	6.00e-116	410.00
IUUC-Ame-011872	Astyanax mexicanus	48.89	9.00e-38	149.00
IUUC-Bta-013325	Bos taurus	93.86	2.00e-177	614.00
IUUC-Cja-019059	Callithrix jacchus	92.11	5.00e-174	603.00
IUUC-Cfa-021036	Canis familiaris	94.16	5.00e-156	543.00
IUUC-Cpo-022369	Cavia porcellus	90.64	3.00e-172	597.00
IUUC-Csa-023585	Chlorocebus sabaeus	92.11	5.00e-175	606.00
IUUC-Cho-024470	Choloepus hoffmanni	85.89	1.00e-113	401.00
IUUC-Dno-029867	Dasypus novemcinctus	89.47	1.00e-172	598.00
IUUC-Dor-030834	Dipodomys ordii	62.97	2.00e-109	388.00
IUUC-Ete-032245	Echinops telfairi	84.14	4.00e-136	477.00
IUUC-Eeu-035353	Erinaceus europaeus	90.35	2.00e-172	598.00
IUUC-Fca-036277	Felis catus	94.15	3.00e-177	613.00
IUUC-Fal-037383	Ficedula albicollis	68.09	8.00e-99	352.00
IUUC-Gmo-038575	Gadus morhua	54.89	1.00e-94	339.00
IUUC-Gga-040658	Gallus gallus	70.25	7.00e-127	446.00
IUUC-Gac-041463	Gasterosteus aculeatus	51.41	2.00e-79	289.00
IUUC-Ggo-045120	Gorilla gorilla	91.23	6.00e-173	599.00
IUUC-Hsa-046247	Homo sapiens	91.52	7.00e-174	602.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	92.40	3.00e-175	607.00
IUUC-Lch-049741	Latimeria chalumnae	66.67	9.00e-110	389.00
IUUC-Loc-052695	Lepisosteus oculatus	57.60	2.00e-101	361.00
IUUC-Laf-054535	Loxodonta africana	89.66	3.00e-170	590.00
IUUC-Mcc-054699	Macaca mulatta	92.11	5.00e-175	606.00
IUUC-Meu-056053	Macropus eugenii	75.80	2.00e-133	468.00
IUUC-Mga-059672	Meleagris gallopavo	64.95	1.00e-71	262.00
IUUC-Mmr-060963	Microcebus murinus	92.98	3.00e-177	613.00
IUUC-Mdo-062694	Monodelphis domestica	74.05	3.00e-129	454.00
IUUC-Mmu-064031	Mus musculus	88.30	3.00e-168	583.00
IUUC-Mpu-066408	Mustela putorius furo	93.57	4.00e-177	613.00
IUUC-Mlu-068184	Myotis lucifugus	91.25	4.00e-172	596.00
IUUC-Nle-069251	Nomascus leucogenys	91.81	2.00e-174	604.00
IUUC-Opr-071156	Ochotona princeps	84.21	9.00e-158	549.00
IUUC-Ont-072683	Oreochromis niloticus	56.39	6.00e-92	330.00
IUUC-Oan-073042	Ornithorhynchus anatinus	75.35	2.00e-122	431.00
IUUC-Ocu-074843	Oryctolagus cuniculus	92.13	8.00e-172	595.00
IUUC-Ola-086929	Oryzias latipes	51.70	2.00e-83	302.00
IUUC-Oga-088237	Otolemur garnettii	92.11	6.00e-175	606.00
IUUC-Oar-089312	Ovis aries	94.94	9.00e-165	572.00
IUUC-Ptr-091625	Pan troglodytes	91.52	2.00e-173	601.00
IUUC-Pan-091902	Papio anubis	92.33	9.00e-167	579.00
IUUC-Psi-094035	Pelodiscus sinensis	72.54	9.00e-124	436.00
IUUC-Pma-094565	Petromyzon marinus	61.33	8.00e-53	199.00
IUUC-Pfo-097070	Poecilia formosa	53.85	2.00e-86	311.00
IUUC-Pab-098007	Pongo abelii	92.11	1.00e-174	605.00
IUUC-Pca-100513	Procavia capensis	73.68	2.00e-101	361.00
IUUC-Pva-102821	Pteropus vampyrus	88.01	6.00e-162	563.00
IUUC-Rno-105836	Rattus norvegicus	88.22	1.00e-170	592.00
IUUC-Sha-106847	Sarcophilus harrisii	70.00	2.00e-87	315.00
IUUC-Sar-113451	Sorex araneus	85.71	1.00e-163	568.00
IUUC-Ssc-115978	Sus scrofa	91.81	2.00e-172	597.00
IUUC-Tgu-116745	Taeniopygia guttata	69.30	2.00e-91	328.00
IUUC-Tru-117945	Takifugu rubripes	52.80	3.00e-75	275.00
IUUC-Tsy-119059	Tarsius syrichta	89.83	2.00e-91	327.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.49	3.00e-89	321.00
IUUC-Tbe-127559	Tupaia belangeri	93.86	5.00e-178	616.00
IUUC-Ttr-128505	Tursiops truncatus	91.81	3.00e-171	593.00
IUUC-Vpa-130350	Vicugna pacos	95.60	1.00e-96	344.00
IUUC-Xtr-132939	Xenopus tropicalis	60.88	2.00e-107	382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence