iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-060143

Ensembl Protein ID

ENSMGAP00000005802.2

UniProt Accession

G1N2E7; G1N2E7_MELGA

Protein Name

Coronin

Gene Name

CORO1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000005787.2	ENSMGAT00000006546.2	ENSMGAP00000005802.2
ENSMGAG00000005787.2	ENSMGAT00000006559.2	ENSMGAP00000005815.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-16	60.0	78	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 78   GHTGPVLDIDWcphNDQVIASGSEDCTVMVWQI 110
           8***********977799*************86 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MRRVVRQSKF RHVFGQAVKN DQCYDDIRVS RVTWDSSFCA VNPRFVAIIV DASGGGAFLV 60
LPLHKTGRID KSYPTVCGHT GPVLDIDWCP HNDQVIASGS EDCTVMVWQI PENGLTLSLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGAGAGATG CTGGCAAGCT TACAAGGCAG AACAGCACCC AGGTGCTGGA GAACAAGGAA 60
TGGCTTGGAG CAGATGTGGA TATGGAGATG CTGGAGTCAT ACAGCCAGAA AAAGTCACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027333--CORO1C
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016600--C:flotillin complex
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0030036--P:actin cytoskeleton organization
GO:0090630--P:activation of GTPase activity
GO:0045184--P:establishment of protein localization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0010762--P:regulation of fibroblast migration
GO:1900027--P:regulation of ruffle assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002236	Ailuropoda melanoleuca	94.50	0.00e+00	947.00
IUUC-Apl-003861	Anas platyrhynchos	99.16	0.00e+00	981.00
IUUC-Aca-005056	Anolis carolinensis	71.49	0.00e+00	735.00
IUUC-Ani-009155	Aspergillus nidulans	42.86	5.00e-98	351.00
IUUC-Aor-010049	Aspergillus oryzae	44.08	4.00e-94	338.00
IUUC-Ame-011256	Astyanax mexicanus	83.09	0.00e+00	791.00
IUUC-Bta-013225	Bos taurus	95.35	0.00e+00	949.00
IUUC-Bci-013935	Botrytis cinerea	43.03	1.00e-99	356.00
IUUC-Cja-019948	Callithrix jacchus	94.30	0.00e+00	945.00
IUUC-Cfa-020591	Canis familiaris	94.93	0.00e+00	949.00
IUUC-Cpo-021480	Cavia porcellus	94.50	0.00e+00	949.00
IUUC-Csa-024152	Chlorocebus sabaeus	94.71	0.00e+00	950.00
IUUC-Cho-024687	Choloepus hoffmanni	94.92	0.00e+00	879.00
IUUC-Cgl-026456	Colletotrichum gloeosporioides	42.04	8.00e-97	347.00
IUUC-Dre-028541	Danio rerio	84.18	0.00e+00	797.00
IUUC-Dno-029552	Dasypus novemcinctus	95.38	0.00e+00	879.00
IUUC-Dor-030989	Dipodomys ordii	71.73	0.00e+00	760.00
IUUC-Dme-032091	Drosophila melanogaster	53.88	4.00e-154	537.00
IUUC-Ete-032839	Echinops telfairi	85.84	0.00e+00	850.00
IUUC-Eca-034118	Equus caballus	94.93	0.00e+00	948.00
IUUC-Eeu-034499	Erinaceus europaeus	65.86	9.00e-169	585.00
IUUC-Fca-035549	Felis catus	94.50	0.00e+00	947.00
IUUC-Fal-037065	Ficedula albicollis	97.68	0.00e+00	977.00
IUUC-Fox-037737	Fusarium oxysporum	42.89	2.00e-94	339.00
IUUC-Fso-038184	Fusarium solani	43.03	6.00e-100	357.00
IUUC-Gmo-038678	Gadus morhua	77.59	0.00e+00	783.00
IUUC-Ggr-039956	Gaeumannomyces graminis	42.64	2.00e-97	348.00
IUUC-Gga-040842	Gallus gallus	100.00	0.00e+00	990.00
IUUC-Gac-041543	Gasterosteus aculeatus	78.66	0.00e+00	781.00
IUUC-Ggo-044477	Gorilla gorilla	94.71	0.00e+00	949.00
IUUC-Hsa-046610	Homo sapiens	94.71	0.00e+00	948.00
IUUC-Itr-048583	Ictidomys tridecemlineatus	94.50	0.00e+00	945.00
IUUC-Lch-050453	Latimeria chalumnae	83.79	0.00e+00	829.00
IUUC-Loc-052911	Lepisosteus oculatus	83.93	0.00e+00	832.00
IUUC-Laf-053416	Loxodonta africana	94.08	0.00e+00	946.00
IUUC-Mcc-055113	Macaca mulatta	94.50	0.00e+00	947.00
IUUC-Meu-056732	Macropus eugenii	79.96	0.00e+00	739.00
IUUC-Mor-056978	Magnaporthe oryzae	39.62	3.00e-100	358.00
IUUC-Mpo-057410	Magnaporthe poae	42.64	8.00e-91	327.00
IUUC-Mla-058883	Melampsora laricipopulina	42.57	5.00e-87	314.00
IUUC-Mmr-061130	Microcebus murinus	94.71	0.00e+00	949.00
IUUC-Mdo-062851	Monodelphis domestica	85.62	0.00e+00	796.00
IUUC-Mmu-063663	Mus musculus	93.66	0.00e+00	941.00
IUUC-Mpu-066179	Mustela putorius furo	94.71	0.00e+00	946.00
IUUC-Mlu-068175	Myotis lucifugus	94.50	0.00e+00	947.00
IUUC-Nle-069161	Nomascus leucogenys	71.49	0.00e+00	762.00
IUUC-Opr-070617	Ochotona princeps	93.87	0.00e+00	910.00
IUUC-Ont-072629	Oreochromis niloticus	82.03	0.00e+00	839.00
IUUC-Oan-073547	Ornithorhynchus anatinus	94.28	0.00e+00	941.00
IUUC-Ocu-074569	Oryctolagus cuniculus	94.29	0.00e+00	946.00
IUUC-Ola-086558	Oryzias latipes	80.50	0.00e+00	832.00
IUUC-Oga-089145	Otolemur garnettii	94.71	0.00e+00	949.00
IUUC-Oar-089654	Ovis aries	94.93	0.00e+00	949.00
IUUC-Ptr-090763	Pan troglodytes	94.71	0.00e+00	949.00
IUUC-Pan-091885	Papio anubis	94.31	0.00e+00	908.00
IUUC-Psi-093011	Pelodiscus sinensis	95.35	0.00e+00	950.00
IUUC-Pno-094994	Phaeosphaeria nodorum	44.28	6.00e-98	351.00
IUUC-Pfo-097309	Poecilia formosa	81.86	0.00e+00	843.00
IUUC-Pab-097542	Pongo abelii	86.68	0.00e+00	847.00
IUUC-Pca-100630	Procavia capensis	80.08	0.00e+00	767.00
IUUC-Pva-102659	Pteropus vampyrus	71.90	0.00e+00	766.00
IUUC-Pgr-103354	Puccinia graminis	41.90	3.00e-90	325.00
IUUC-Ptt-103735	Puccinia triticina	35.27	3.00e-69	255.00
IUUC-Pte-104194	Pyrenophora teres	43.14	2.00e-98	353.00
IUUC-Pyt-104437	Pyrenophora triticirepentis	43.14	1.00e-98	353.00
IUUC-Rno-105330	Rattus norvegicus	94.29	0.00e+00	948.00
IUUC-Sha-106695	Sarcophilus harrisii	92.67	0.00e+00	762.00
IUUC-Spo-108364	Schizosaccharomyces pombe	43.36	3.00e-98	352.00
IUUC-Sar-113292	Sorex araneus	74.18	1.00e-175	608.00
IUUC-Ssc-115348	Sus scrofa	94.93	0.00e+00	947.00
IUUC-Tgu-116597	Taeniopygia guttata	97.89	0.00e+00	972.00
IUUC-Tru-118425	Takifugu rubripes	80.97	0.00e+00	826.00
IUUC-Tsy-119223	Tarsius syrichta	84.06	0.00e+00	739.00
IUUC-Tni-120610	Tetraodon nigroviridis	80.34	0.00e+00	822.00
IUUC-Tbe-127679	Tupaia belangeri	85.31	0.00e+00	632.00
IUUC-Ttr-129226	Tursiops truncatus	85.38	0.00e+00	819.00
IUUC-Vda-129792	Verticillium dahliae	42.39	2.00e-95	342.00
IUUC-Vpa-130339	Vicugna pacos	96.40	0.00e+00	693.00
IUUC-Xtr-132873	Xenopus tropicalis	74.32	0.00e+00	748.00
IUUC-Xma-134047	Xiphophorus maculatus	81.86	0.00e+00	842.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence