iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062413

UUCD1 version

UUC-MoD-01020

Ensembl Protein ID

ENSMODP00000017386.2

UniProt Accession

F6VSA5; F6VSA5_MONDO

Protein Name

Uncharacterized protein

Gene Name

UBE2D4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000013897.2	ENSMODT00000017706.2	ENSMODP00000017386.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.40e-54	183.8	1	131
UBD/UBC-like/UBD_UBC	5.00e-81	269.8	1	134

Active Site

Position(s)	Description	Evidence
77	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 5    elkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWs 93
           el++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  ++Ws
   Q: 1    ELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR--SQWS 86
           799*****************.9************************************************************9..**** PP
   S: 94   palsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           pal+v++vllsi+sll++pnp++pl  e+a+++k++r +y++ +r
   Q: 87   PALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADRDKYNRLAR 131
           *****************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 5    elkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaal 93
           el dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqws+al
   Q: 1    ELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPAL 89
           899************************************************************************************** PP
   S: 94   tlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           t+skvlls+csll+d++pddplv+eia+ yk+d++ky+r arewt
   Q: 90   TVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADRDKYNRLAREWT 134
           ********************************************8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

ELTDLQRDPP AQCSAGPVGD DLFHWQATIM GPNDSPYQGG VFFLTIHFPT DYPFKPPKVA 60
FTTKIYHPNI NSNGSICLDI LRSQWSPALT VSKVLLSICS LLCDPNPDDP LVPEIAHTYK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAATTAACTG ACTTGCAGAG GGACCCTCCC GCCCAGTGCT CAGCAGGACC TGTGGGTGAT 60
GATTGTAAGT AATGGGTTTT TAGGATTTCT GGTTAAAGGA GTCTTGCAAA GAGATCCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008709	Aspergillus flavus	81.88	8.00e-69	254.00
IUUC-Cja-019014	Callithrix jacchus	98.56	2.00e-80	290.00
IUUC-Cpo-021897	Cavia porcellus	98.56	5.00e-80	289.00
IUUC-Csa-023377	Chlorocebus sabaeus	98.56	4.00e-80	290.00
IUUC-Eca-033231	Equus caballus	99.28	2.00e-80	290.00
IUUC-Gac-042534	Gasterosteus aculeatus	92.81	2.00e-75	273.00
IUUC-Mmr-061446	Microcebus murinus	96.40	9.00e-79	285.00
IUUC-Oan-073026	Ornithorhynchus anatinus	99.28	2.00e-80	291.00
IUUC-Ocu-073914	Oryctolagus cuniculus	97.12	4.00e-79	286.00
IUUC-Pan-092614	Papio anubis	99.28	2.00e-80	290.00
IUUC-Tsy-118832	Tarsius syrichta	97.12	3.00e-78	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence