iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073914

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02061871

Gene Name

UBE2D4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000008900.2	ENSOCUT00000008900.2	ENSOCUP00000007683.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.50e-55	185.6	9	141
UBD/UBC-like/UBD_UBC	1.30e-80	268.3	10	144

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
            +el++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+gg+F l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  ++
   Q: 9    FHELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPTDSPYQGGLFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR--SQ 94
           579*******************.9************************************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           Wspal+v++vllsi+sll++pnp++pl  e+a+++k++re+y++ +r
   Q: 95   WSPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAR 141
           *******************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 4    kelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaa 92
           +el dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+gg fflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqws+a
   Q: 10   HELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPTDSPYQGGLFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPA 98
           79*************************************************************************************** PP
   S: 93   ltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           lt+skvlls+csll+d++pddplv+eia+ yk+d+eky+r arewt
   Q: 99   LTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAREWT 144
           *********************************************8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

VTLVQLHLFH ELTDLQRDPP AQCSAGPVGD DLFHWQATIM GPTDSPYQGG LFFLTIHFPT 60
DYPFKPPKVA FTTKIYHPNI NSNGSICLDI LRSQWSPALT VSKVLLSICS LLCDPNPDDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGACCTTGG TGCAGCTTCA CCTCTTTCAT GTCTGTTTTT CGAGCCAGGA GAGGGCCCTG 60
TGAGCACCTT GTCTCCAGCC CCTCCCACCA AGAGACTCTG CGGGCAGGCA GGAGGCTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008709	Aspergillus flavus	79.17	8.00e-69	254.00
IUUC-Cja-019014	Callithrix jacchus	91.84	5.00e-80	289.00
IUUC-Cpo-021897	Cavia porcellus	97.12	3.00e-79	286.00
IUUC-Csa-023377	Chlorocebus sabaeus	92.62	6.00e-80	289.00
IUUC-Eca-033231	Equus caballus	97.84	1.00e-79	288.00
IUUC-Gac-042534	Gasterosteus aculeatus	90.14	4.00e-75	273.00
IUUC-Mmr-061446	Microcebus murinus	94.96	5.00e-78	282.00
IUUC-Mdo-062413	Monodelphis domestica	97.12	3.00e-79	286.00
IUUC-Oan-073026	Ornithorhynchus anatinus	97.14	8.00e-80	288.00
IUUC-Pan-092614	Papio anubis	97.84	1.00e-79	287.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence