iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074649

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02060828

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015386.3	ENSOCUT00000015387.3	ENSOCUP00000013221.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-18	66.5	198	231
UBD/Beta-Prp	4.00e-40	137.9	269	407

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H+ +v+c++  ++++vsGs+D t kvW l +g+l
   Q: 198  HEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL 231
           99*******9449***************999875 PP

UBD/Beta-Prp

   S: 161  vrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs.sDg 244
           +r+Wdl++g+l+++l ++  +    l++ +++   l+s+++d++v++wdl+  + +cv+++++ h+++ ++++++  +++l++gs   g
   Q: 269  LRIWDLNSGQLMTHLGSDFPPGAGVLDVMYESpSTLLSCGYDTYVRYWDLRtsARKCVMEWEEpHDSTLYCLQTD-GNHLLATGSsYYG 356
           79*************99999999****99999789****************99899******999**********.999999999789* PP
   S: 245  siriWdlrsgdllktlqlhn.ssvisvavlsfgdnvlvlgsedskvniwklk 295
           ++r+Wd r++ +l+++ l+    +++v +l+f+  +l+++ +  ++++++++
   Q: 357  VVRLWDRRQRACLHAFPLTStPLSSPVYCLRFTTTHLYAALS-YNLHVLDFR 407
           ******************99667889********99998866.467777776 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

GAAMAAAAEE EAAARPPAAR PTAGSALWRL PEELLLLICS YLDMRALGRL TQVCRWLRFT 60
SCDLLWRRIA RASLNSGFRL GTDLMTSVPV KERVKVSQNW RLGRCREGVL LKWRCRQMPW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCGGCCA TGGCGGCAGC AGCTGAGGAG GAGGCAGCGG CTCGCCCGCC CGCCGCGCGC 60
CCGACTGCTG GGTCCGCGCT GTGGCGCCTG CCGGAGGAGC TGCTGCTGCT CATCTGCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	95.72	0.00e+00	741.00
IUUC-Apl-003837	Anas platyrhynchos	72.36	1.00e-142	498.00
IUUC-Aca-004776	Anolis carolinensis	68.19	5.00e-138	484.00
IUUC-Ame-010651	Astyanax mexicanus	63.04	3.00e-115	408.00
IUUC-Bta-013495	Bos taurus	95.45	0.00e+00	704.00
IUUC-Cja-018901	Callithrix jacchus	96.75	0.00e+00	706.00
IUUC-Cfa-021251	Canis familiaris	94.65	0.00e+00	732.00
IUUC-Cpo-021750	Cavia porcellus	93.85	0.00e+00	650.00
IUUC-Csa-024026	Chlorocebus sabaeus	95.93	0.00e+00	733.00
IUUC-Cho-024496	Choloepus hoffmanni	74.80	9.00e-154	536.00
IUUC-Cin-025142	Ciona intestinalis	30.43	3.00e-22	98.20
IUUC-Csv-025883	Ciona savignyi	36.71	1.00e-63	236.00
IUUC-Dre-027447	Danio rerio	59.11	1.00e-130	459.00
IUUC-Dno-029572	Dasypus novemcinctus	80.54	2.00e-167	582.00
IUUC-Dor-030982	Dipodomys ordii	88.35	0.00e+00	658.00
IUUC-Dme-031804	Drosophila melanogaster	22.70	4.00e-12	65.50
IUUC-Ete-032917	Echinops telfairi	93.85	0.00e+00	648.00
IUUC-Eca-033969	Equus caballus	95.66	0.00e+00	698.00
IUUC-Eeu-034850	Erinaceus europaeus	84.82	0.00e+00	634.00
IUUC-Fca-036182	Felis catus	89.30	0.00e+00	675.00
IUUC-Fal-037391	Ficedula albicollis	68.53	1.00e-146	512.00
IUUC-Gmo-038632	Gadus morhua	56.48	3.00e-126	444.00
IUUC-Gga-040783	Gallus gallus	72.78	8.00e-158	549.00
IUUC-Gac-042314	Gasterosteus aculeatus	55.56	9.00e-108	383.00
IUUC-Ggo-044739	Gorilla gorilla	95.93	0.00e+00	732.00
IUUC-Hsa-046705	Homo sapiens	96.48	0.00e+00	706.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	97.58	1.00e-170	591.00
IUUC-Loc-052397	Lepisosteus oculatus	65.97	4.00e-138	484.00
IUUC-Laf-054544	Loxodonta africana	95.11	0.00e+00	651.00
IUUC-Meu-056363	Macropus eugenii	60.00	3.00e-105	374.00
IUUC-Mga-059275	Meleagris gallopavo	73.67	3.00e-144	504.00
IUUC-Mmr-060906	Microcebus murinus	95.93	0.00e+00	731.00
IUUC-Mdo-062400	Monodelphis domestica	78.07	1.00e-173	602.00
IUUC-Mmu-063556	Mus musculus	91.60	0.00e+00	701.00
IUUC-Mpu-066500	Mustela putorius furo	95.45	0.00e+00	739.00
IUUC-Mlu-068074	Myotis lucifugus	95.38	0.00e+00	652.00
IUUC-Nle-069601	Nomascus leucogenys	96.21	0.00e+00	734.00
IUUC-Opr-070904	Ochotona princeps	88.65	4.00e-145	506.00
IUUC-Ont-072679	Oreochromis niloticus	56.25	2.00e-118	419.00
IUUC-Oan-073434	Ornithorhynchus anatinus	71.96	6.00e-81	293.00
IUUC-Ola-087336	Oryzias latipes	49.22	2.00e-101	362.00
IUUC-Oga-088590	Otolemur garnettii	94.31	0.00e+00	694.00
IUUC-Oar-090178	Ovis aries	92.53	0.00e+00	662.00
IUUC-Pan-092881	Papio anubis	96.21	0.00e+00	733.00
IUUC-Pfo-096176	Poecilia formosa	56.28	1.00e-111	396.00
IUUC-Pab-098285	Pongo abelii	96.21	0.00e+00	735.00
IUUC-Pca-100888	Procavia capensis	89.57	0.00e+00	677.00
IUUC-Pva-102184	Pteropus vampyrus	81.57	1.00e-172	598.00
IUUC-Rno-105668	Rattus norvegicus	93.22	0.00e+00	710.00
IUUC-Sha-106629	Sarcophilus harrisii	77.95	1.00e-155	541.00
IUUC-Ssc-116183	Sus scrofa	96.26	0.00e+00	744.00
IUUC-Tgu-116630	Taeniopygia guttata	71.73	1.00e-165	575.00
IUUC-Tru-118761	Takifugu rubripes	52.11	3.00e-114	404.00
IUUC-Tni-120651	Tetraodon nigroviridis	52.48	3.00e-60	224.00
IUUC-Ttr-128582	Tursiops truncatus	94.65	0.00e+00	696.00
IUUC-Vpa-130431	Vicugna pacos	76.19	5.00e-97	347.00
IUUC-Xtr-132655	Xenopus tropicalis	66.40	5.00e-144	503.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence