iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107181

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01017035

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000011898.1	ENSSHAT00000014029.1	ENSSHAP00000013912.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-41	136.9	581	616
UBD/Beta-Prp	3.30e-66	223.6	2	210

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           gHt+++t+la+   +d++lvs+++Dgt++vWD+ + 
   Q: 581  GHTAKITSLAWsphHDGRLVSACYDGTVQVWDVLRE 616
           8***********8766****************8665 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           l +l gh++ v+  +fs++     + +++s+D+t+k+wd++t++ v   + h++++ +l++sp  +d +vsG++  ++ ++ ++++  +
   Q: 2    LGELVGHTERVSGFTFSHHVGqttFCASSSDDGTVKIWDVDTRTAVTEHTLHQNTISALHWSPkVKDLIVSGDEKGIVICY-WNNRNDS 89
           57899************99777889**************************************556**************7.6666666 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...........fdsng............. 192
           +  + ++ +++ c++ +p   +l++ G +D++v + d+ + g++l++l+g h+d ++s++           +   +             
   Q: 90   Q-HFFPEPRTIFCITCSPHHeDLVAIGYKDGMVVVIDIsRKGDILHRLRG-HDDEIHSIAwcpllgeecltI---Rpeensdeheipng 173
           6.6788888899998888888*****************999********9.*********666666666662...04446677788888 PP
   S: 193  ...........kelvsgsldgtvklwdlqtgecvrtl 218
                       +l++gs+d+t+++w++++g+ v+tl
   Q: 174  kvvqqtpvakgCYLATGSKDQTIRIWSCSRGRGVMTL 210
           99999999999********************999987 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

VLGELVGHTE RVSGFTFSHH VGQTTFCASS SDDGTVKIWD VDTRTAVTEH TLHQNTISAL 60
HWSPKVKDLI VSGDEKGIVI CYWNNRNDSQ HFFPEPRTIF CITCSPHHED LVAIGYKDGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTAGATCAT CTCCAAGGAT CCTTCAGCCA GAACAAGAAA AGGTGACTAC CACTGATGAT 60
TAGAAACTTA AAAAAAAAAT CCTTGAGGCC CATATACATT TAATCTGCTT GATATGTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	73.71	0.00e+00	2101.00
IUUC-Apl-003586	Anas platyrhynchos	66.20	0.00e+00	1766.00
IUUC-Aca-004956	Anolis carolinensis	65.60	0.00e+00	1916.00
IUUC-Ame-010753	Astyanax mexicanus	65.87	0.00e+00	988.00
IUUC-Bta-012315	Bos taurus	73.95	0.00e+00	2118.00
IUUC-Cja-019334	Callithrix jacchus	73.15	0.00e+00	2123.00
IUUC-Cfa-021254	Canis familiaris	74.25	0.00e+00	2161.00
IUUC-Cpo-021984	Cavia porcellus	69.85	0.00e+00	1954.00
IUUC-Csa-023650	Chlorocebus sabaeus	73.75	0.00e+00	2099.00
IUUC-Cho-024860	Choloepus hoffmanni	70.17	0.00e+00	1976.00
IUUC-Cin-025778	Ciona intestinalis	37.76	0.00e+00	650.00
IUUC-Csv-026313	Ciona savignyi	41.34	8.00e-157	547.00
IUUC-Dre-028096	Danio rerio	67.36	0.00e+00	1003.00
IUUC-Dno-029799	Dasypus novemcinctus	78.54	0.00e+00	1898.00
IUUC-Dor-030885	Dipodomys ordii	64.93	1.00e-142	501.00
IUUC-Ete-032918	Echinops telfairi	68.91	0.00e+00	1970.00
IUUC-Eca-034144	Equus caballus	73.67	0.00e+00	2117.00
IUUC-Eeu-034843	Erinaceus europaeus	68.67	0.00e+00	1541.00
IUUC-Fca-035948	Felis catus	73.77	0.00e+00	2120.00
IUUC-Fal-037303	Ficedula albicollis	65.70	0.00e+00	1883.00
IUUC-Gmo-039591	Gadus morhua	54.59	0.00e+00	810.00
IUUC-Gga-040570	Gallus gallus	65.11	0.00e+00	1755.00
IUUC-Gac-042646	Gasterosteus aculeatus	52.81	0.00e+00	1316.00
IUUC-Ggo-045605	Gorilla gorilla	70.97	0.00e+00	1526.00
IUUC-Hsa-046122	Homo sapiens	73.82	0.00e+00	2101.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	79.00	0.00e+00	1925.00
IUUC-Lch-050489	Latimeria chalumnae	50.57	0.00e+00	904.00
IUUC-Loc-052259	Lepisosteus oculatus	64.40	0.00e+00	966.00
IUUC-Laf-053338	Loxodonta africana	74.31	0.00e+00	2131.00
IUUC-Mcc-055442	Macaca mulatta	73.95	0.00e+00	2102.00
IUUC-Meu-056245	Macropus eugenii	80.67	0.00e+00	1033.00
IUUC-Mga-060202	Meleagris gallopavo	64.97	0.00e+00	1816.00
IUUC-Mmr-061730	Microcebus murinus	73.34	0.00e+00	2097.00
IUUC-Mdo-062880	Monodelphis domestica	92.55	0.00e+00	2689.00
IUUC-Mmu-063930	Mus musculus	70.95	0.00e+00	1981.00
IUUC-Mpu-066605	Mustela putorius furo	73.80	0.00e+00	2140.00
IUUC-Mlu-067765	Myotis lucifugus	73.16	0.00e+00	2154.00
IUUC-Nle-069183	Nomascus leucogenys	73.91	0.00e+00	2068.00
IUUC-Opr-070659	Ochotona princeps	61.72	0.00e+00	938.00
IUUC-Ont-072356	Oreochromis niloticus	64.19	0.00e+00	986.00
IUUC-Oan-073056	Ornithorhynchus anatinus	76.58	0.00e+00	2174.00
IUUC-Ocu-073881	Oryctolagus cuniculus	74.12	0.00e+00	2181.00
IUUC-Ola-087120	Oryzias latipes	60.62	5.00e-59	219.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.62	4.00e-31	130.00
IUUC-Oga-088343	Otolemur garnettii	74.25	0.00e+00	2122.00
IUUC-Oar-089257	Ovis aries	73.87	0.00e+00	2144.00
IUUC-Ptr-090497	Pan troglodytes	73.82	0.00e+00	2103.00
IUUC-Pan-092638	Papio anubis	73.77	0.00e+00	2091.00
IUUC-Psi-093096	Pelodiscus sinensis	69.34	0.00e+00	1785.00
IUUC-Pma-094571	Petromyzon marinus	40.68	6.00e-81	294.00
IUUC-Pfo-096348	Poecilia formosa	49.29	0.00e+00	1352.00
IUUC-Pab-098153	Pongo abelii	73.76	0.00e+00	2138.00
IUUC-Pca-100957	Procavia capensis	68.47	0.00e+00	1941.00
IUUC-Pva-102439	Pteropus vampyrus	74.64	0.00e+00	2163.00
IUUC-Rno-105891	Rattus norvegicus	70.74	0.00e+00	1963.00
IUUC-Ssc-115413	Sus scrofa	73.27	0.00e+00	2143.00
IUUC-Tgu-117082	Taeniopygia guttata	65.28	0.00e+00	1839.00
IUUC-Tru-118491	Takifugu rubripes	61.79	0.00e+00	929.00
IUUC-Tsy-119629	Tarsius syrichta	83.04	1.00e-149	524.00
IUUC-Tni-120240	Tetraodon nigroviridis	62.21	0.00e+00	924.00
IUUC-Tbe-127673	Tupaia belangeri	64.01	0.00e+00	1719.00
IUUC-Ttr-128562	Tursiops truncatus	70.76	0.00e+00	2038.00
IUUC-Vpa-130596	Vicugna pacos	75.64	0.00e+00	1588.00
IUUC-Xtr-132469	Xenopus tropicalis	57.12	0.00e+00	1625.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence