iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sit-109697

Ensembl Protein ID

Si033952m

UniProt Accession

K4A4Z8; K4A4Z8_SETIT

Genbank Protein ID

KQK87458.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM003536

Gene Name

LOC101759451; SETIT_033952mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Si033952m.g	Si033952m	Si033952m

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.40e-39	131.2	50	86
UBD/Beta-Prp	1.20e-77	262.0	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhaTQPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********6449********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
           t +++++++++ + f+p +++++++  +g i+ wd+++g+ll ++ +h+++v+ v f+ +++++v+g++D+ ikvw+++t  c+ tl+gh d++++++f+
   Q: 3    TKFETKSNRVKGLSFHPRRPWILASLHSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFTLHGHLDYIRTVQFH 102
           67889999******************************************************************************************** PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...........................ktgkllrtlt 176
            +  ++vs+s+d+tir+w++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                             + + + l+
   Q: 103  HEYPWIVSASDDQTIRIWNWQSRTCVA-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgalrkktvspaddilrltqmntdlfggVDAVVKYVLE 201
           ***************************.*************************************************97777777777644444444446 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavls 274
           g h++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+siriWd ++++ ++t+ +++++++  a+ +
   Q: 202  G-HDRGVNWASFHPSLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRIWDATKRTGIQTFRREHDRFWILAA-H 299
           6.********************************777668**********************************************************.6 PP
   S: 275  fgdnvlvlgsedskvniwklkknep 299
           ++ n l++g  ds   ++kl++++p
   Q: 300  PEMNLLAAG-HDSGMIVFKLERERP 323
           666655555.689999999988765 PP

Organism

Setaria italica

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPR RPWILASLHS GVIQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
ATQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCTAGAGG GTCTCGGGCT TCACCCGCCG CCGTGGCCGG GGACGCCAGG CCGGGAGGAT 60
GCTGACCAAG TTCGAGACGA AGAGCAACCG GGTGAAGGGC CTGAGCTTCC ACCCGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

sita:101759451

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	91.47	0.00e+00	2261.00
IUUC-Aml-001758	Ailuropoda melanoleuca	54.00	0.00e+00	1351.00
IUUC-Atr-002493	Amborella trichopoda	81.07	0.00e+00	1986.00
IUUC-Apl-003385	Anas platyrhynchos	49.35	0.00e+00	1031.00
IUUC-Aca-005154	Anolis carolinensis	78.43	2.00e-95	340.00
IUUC-Aly-005526	Arabidopsis lyrata	75.29	0.00e+00	1867.00
IUUC-Ath-007058	Arabidopsis thaliana	78.36	0.00e+00	1952.00
IUUC-Ago-007992	Ashbya gossypii	43.10	0.00e+00	974.00
IUUC-Acl-008027	Aspergillus clavatus	54.46	0.00e+00	959.00
IUUC-Afl-008644	Aspergillus flavus	47.69	0.00e+00	1117.00
IUUC-Afu-008964	Aspergillus fumigatus	54.62	0.00e+00	965.00
IUUC-Ani-009379	Aspergillus nidulans	55.35	0.00e+00	974.00
IUUC-Ang-009756	Aspergillus niger	47.13	0.00e+00	1125.00
IUUC-Aor-010174	Aspergillus oryzae	47.69	0.00e+00	1117.00
IUUC-Ate-010302	Aspergillus terreus	47.04	0.00e+00	1148.00
IUUC-Ame-011229	Astyanax mexicanus	53.60	0.00e+00	1317.00
IUUC-Bgr-012300	Blumeria graminis	46.74	0.00e+00	1075.00
IUUC-Bta-012524	Bos taurus	54.47	0.00e+00	1346.00
IUUC-Bci-013781	Botrytis cinerea	47.05	0.00e+00	1124.00
IUUC-Bdi-014549	Brachypodium distachyon	89.42	0.00e+00	2277.00
IUUC-Bol-015925	Brassica oleracea	76.41	0.00e+00	1915.00
IUUC-Bra-016978	Brassica rapa	76.89	0.00e+00	1928.00
IUUC-Cel-018115	Caenorhabditis elegans	54.81	0.00e+00	935.00
IUUC-Cja-019107	Callithrix jacchus	53.40	0.00e+00	1336.00
IUUC-Cfa-020675	Canis familiaris	53.66	0.00e+00	1324.00
IUUC-Cpo-021813	Cavia porcellus	54.55	0.00e+00	1360.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	69.47	0.00e+00	1238.00
IUUC-Csa-023523	Chlorocebus sabaeus	54.63	0.00e+00	1367.00
IUUC-Cho-024704	Choloepus hoffmanni	68.37	4.00e-131	462.00
IUUC-Cin-025572	Ciona intestinalis	50.80	0.00e+00	1258.00
IUUC-Csv-025864	Ciona savignyi	56.79	0.00e+00	974.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.14	0.00e+00	976.00
IUUC-Cne-027053	Cryptococcus neoformans	58.16	0.00e+00	1023.00
IUUC-Cme-027222	Cyanidioschyzon merolae	42.97	7.00e-147	514.00
IUUC-Dre-027421	Danio rerio	54.30	0.00e+00	1344.00
IUUC-Dno-029303	Dasypus novemcinctus	54.55	0.00e+00	1361.00
IUUC-Dor-030290	Dipodomys ordii	52.82	4.00e-165	575.00
IUUC-Dse-031543	Dothistroma septosporum	45.53	0.00e+00	1050.00
IUUC-Dme-031945	Drosophila melanogaster	60.22	0.00e+00	1019.00
IUUC-Ete-032873	Echinops telfairi	52.37	0.00e+00	1194.00
IUUC-Eca-033773	Equus caballus	53.64	0.00e+00	1321.00
IUUC-Eeu-034874	Erinaceus europaeus	41.37	0.00e+00	655.00
IUUC-Fca-035739	Felis catus	53.82	0.00e+00	1321.00
IUUC-Fal-037263	Ficedula albicollis	51.14	0.00e+00	1197.00
IUUC-Fox-037738	Fusarium oxysporum	47.17	0.00e+00	1126.00
IUUC-Fso-038153	Fusarium solani	46.84	0.00e+00	1117.00
IUUC-Gmo-039602	Gadus morhua	50.48	0.00e+00	1219.00
IUUC-Ggr-039931	Gaeumannomyces graminis	53.99	0.00e+00	961.00
IUUC-Gga-040590	Gallus gallus	54.45	0.00e+00	1355.00
IUUC-Gac-041318	Gasterosteus aculeatus	54.03	0.00e+00	1335.00
IUUC-Gma-043894	Glycine max	77.31	0.00e+00	1977.00
IUUC-Ggo-045029	Gorilla gorilla	54.16	0.00e+00	1357.00
IUUC-Hsa-046078	Homo sapiens	54.16	0.00e+00	1357.00
IUUC-Hvu-047556	Hordeum vulgare	89.66	0.00e+00	2281.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	45.84	0.00e+00	752.00
IUUC-Kpa-049256	Komagataella pastoris	52.17	0.00e+00	906.00
IUUC-Lch-049706	Latimeria chalumnae	54.15	0.00e+00	1346.00
IUUC-Lpe-051316	Leersia perrieri	93.85	0.00e+00	2279.00
IUUC-Loc-051867	Lepisosteus oculatus	49.53	0.00e+00	811.00
IUUC-Lma-053138	Leptosphaeria maculans	55.16	0.00e+00	996.00
IUUC-Laf-053510	Loxodonta africana	55.01	0.00e+00	1374.00
IUUC-Mcc-055836	Macaca mulatta	54.17	0.00e+00	1353.00
IUUC-Meu-056238	Macropus eugenii	56.36	0.00e+00	771.00
IUUC-Mor-057172	Magnaporthe oryzae	46.20	0.00e+00	1100.00
IUUC-Mpo-057300	Magnaporthe poae	46.38	0.00e+00	1092.00
IUUC-Mtr-058248	Medicago truncatula	77.23	0.00e+00	1972.00
IUUC-Mla-059019	Melampsora laricipopulina	49.92	0.00e+00	1211.00
IUUC-Mga-059499	Meleagris gallopavo	54.44	0.00e+00	1352.00
IUUC-Mvi-060336	Microbotryum violaceum	50.73	0.00e+00	1209.00
IUUC-Mmr-061102	Microcebus murinus	54.16	0.00e+00	1346.00
IUUC-Mdo-062594	Monodelphis domestica	54.80	0.00e+00	1385.00
IUUC-Mmu-063736	Mus musculus	54.28	0.00e+00	1346.00
IUUC-Mac-065272	Musa acuminata	73.50	0.00e+00	1850.00
IUUC-Mpu-066701	Mustela putorius furo	54.52	0.00e+00	1355.00
IUUC-Mlu-067392	Myotis lucifugus	54.93	0.00e+00	1345.00
IUUC-Nfi-068270	Neosartorya fischeri	54.82	0.00e+00	964.00
IUUC-Ncr-068892	Neurospora crassa	47.05	0.00e+00	1099.00
IUUC-Nle-069634	Nomascus leucogenys	65.42	0.00e+00	944.00
IUUC-Opr-070952	Ochotona princeps	41.78	0.00e+00	651.00
IUUC-Ont-072488	Oreochromis niloticus	53.92	0.00e+00	1330.00
IUUC-Ocu-074211	Oryctolagus cuniculus	54.47	0.00e+00	1358.00
IUUC-Oba-075761	Oryza barthii	92.53	0.00e+00	2277.00
IUUC-Obr-076429	Oryza brachyantha	92.62	0.00e+00	2271.00
IUUC-Ogl-077364	Oryza glaberrima	92.86	0.00e+00	2284.00
IUUC-Ogu-078257	Oryza glumaepatula	92.28	0.00e+00	2214.00
IUUC-Oin-079274	Oryza indica	92.70	0.00e+00	2281.00
IUUC-Olo-080466	Oryza longistaminata	96.45	0.00e+00	1667.00
IUUC-Ome-081993	Oryza meridionalis	94.61	0.00e+00	1514.00
IUUC-Oni-082874	Oryza nivara	92.78	0.00e+00	2280.00
IUUC-Opu-083885	Oryza punctata	93.03	0.00e+00	2298.00
IUUC-Oru-084274	Oryza rufipogon	92.78	0.00e+00	2282.00
IUUC-Osa-085565	Oryza sativa	92.78	0.00e+00	2282.00
IUUC-Ola-086921	Oryzias latipes	53.06	0.00e+00	1320.00
IUUC-Olu-087639	Ostreococcus lucimarinus	60.37	0.00e+00	1529.00
IUUC-Oga-087991	Otolemur garnettii	51.81	0.00e+00	1268.00
IUUC-Oar-089590	Ovis aries	54.39	0.00e+00	1359.00
IUUC-Ptr-090808	Pan troglodytes	54.24	0.00e+00	1359.00
IUUC-Pan-092475	Papio anubis	54.43	0.00e+00	1358.00
IUUC-Psi-093044	Pelodiscus sinensis	53.65	0.00e+00	884.00
IUUC-Pno-094839	Phaeosphaeria nodorum	45.58	0.00e+00	1044.00
IUUC-Ppa-095785	Physcomitrella patens	69.39	0.00e+00	1785.00
IUUC-Pfo-097493	Poecilia formosa	54.00	0.00e+00	1328.00
IUUC-Pab-098497	Pongo abelii	54.55	0.00e+00	1368.00
IUUC-Pop-100086	Populus trichocarpa	81.24	0.00e+00	2023.00
IUUC-Pca-100413	Procavia capensis	60.07	0.00e+00	690.00
IUUC-Ppe-101392	Prunus persica	80.92	0.00e+00	2053.00
IUUC-Pva-102126	Pteropus vampyrus	52.08	0.00e+00	1283.00
IUUC-Pgr-103376	Puccinia graminis	49.96	0.00e+00	1217.00
IUUC-Ptt-103978	Puccinia triticina	44.77	0.00e+00	972.00
IUUC-Pte-104126	Pyrenophora teres	54.46	0.00e+00	946.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	45.72	5.00e-177	614.00
IUUC-Rno-105428	Rattus norvegicus	54.59	0.00e+00	1353.00
IUUC-Sce-106464	Saccharomyces cerevisiae	41.52	0.00e+00	936.00
IUUC-Sha-107301	Sarcophilus harrisii	53.88	0.00e+00	1343.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.46	0.00e+00	1067.00
IUUC-Spo-108217	Schizosaccharomyces pombe	44.24	0.00e+00	1053.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	54.22	0.00e+00	956.00
IUUC-Smo-109582	Selaginella moellendorffii	74.20	0.00e+00	1363.00
IUUC-Sly-111759	Solanum lycopersicum	79.44	0.00e+00	2021.00
IUUC-Stu-112564	Solanum tuberosum	79.52	0.00e+00	2020.00
IUUC-Sar-113313	Sorex araneus	41.61	0.00e+00	632.00
IUUC-Sbi-114388	Sorghum bicolor	97.54	0.00e+00	2363.00
IUUC-Sre-115209	Sporisorium reilianum	55.07	0.00e+00	997.00
IUUC-Ssc-115933	Sus scrofa	54.47	0.00e+00	1360.00
IUUC-Tgu-117109	Taeniopygia guttata	49.36	6.00e-101	360.00
IUUC-Tru-117772	Takifugu rubripes	53.96	0.00e+00	1308.00
IUUC-Tsy-119105	Tarsius syrichta	51.78	0.00e+00	1021.00
IUUC-Tni-120556	Tetraodon nigroviridis	42.00	0.00e+00	882.00
IUUC-Tca-121545	Theobroma cacao	84.59	0.00e+00	1522.00
IUUC-Tre-121951	Trichoderma reesei	54.03	0.00e+00	970.00
IUUC-Tvi-122359	Trichoderma virens	54.56	0.00e+00	978.00
IUUC-Tae-123611	Triticum aestivum	91.47	0.00e+00	2262.00
IUUC-Tur-126754	Triticum urartu	89.99	0.00e+00	2222.00
IUUC-Tme-127170	Tuber melanosporum	47.61	0.00e+00	1170.00
IUUC-Tbe-127882	Tupaia belangeri	68.39	4.00e-128	452.00
IUUC-Ttr-128217	Tursiops truncatus	52.16	0.00e+00	1282.00
IUUC-Uma-129337	Ustilago maydis	55.07	0.00e+00	996.00
IUUC-Vda-129828	Verticillium dahliae	46.68	0.00e+00	1107.00
IUUC-Vpa-130537	Vicugna pacos	53.92	0.00e+00	1333.00
IUUC-Vvi-130958	Vitis vinifera	80.02	0.00e+00	2013.00
IUUC-Xtr-132857	Xenopus tropicalis	52.07	0.00e+00	1267.00
IUUC-Xma-133138	Xiphophorus maculatus	53.92	0.00e+00	1326.00
IUUC-Yli-134399	Yarrowia lipolytica	49.36	0.00e+00	838.00
IUUC-Zma-135612	Zea mays	92.86	0.00e+00	2369.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence