iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065827

Ensembl Protein ID

ENSMPUP00000009968.1

UniProt Accession

M3YF61; M3YF61_MUSPF

Genbank Protein ID

ENSMPUP00000009968

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01063381

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000010043.1	ENSMPUT00000010128.1	ENSMPUP00000009968.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.90e-30	101.4	596	628
UBD/Beta-Prp	2.00e-45	155.2	592	805

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+   +  +l+s+s Dgt+++W+++
   Q: 596  GHTDAVWGLAYsaaH-QRLLSCSADGTLRLWNTT 628
           8**********9853.89**************76 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk......ghedsvlslsfspsgdklvsGshdrtirvwdletgqc 128
             l gh+++v+ + +s   + l+++s D+t+++w+     +  ++       g  +sv ++s++p  +++v+  +  +  ++++et+q 
   Q: 592  GPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFndnqelGIPASVDLVSSDP--SHMVASFSKGYTSIFNMETQQR 678
           5689******************************8887766666661444444444555566666..8888888899************ PP
   S: 129  lee.....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtg 212
           + +       ++ +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l+++
   Q: 679  ILTlesnlDSTNSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESK 766
           **966653222333346677789999**************************98.********************************** PP
   S: 213  ecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           +c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 767  TCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 805
           **********999999******************97655 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MDEQAGPGVF FSNNHPGAGG AKGLGPLAEA AAAGDGAAAA GAARAQYSLP GILHFLQHEW 60
ARFEVERAQW EVERAELQAQ IAFLQGERKG QEILKKDLVR RIKMLEYALK QERAKYHKLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCGACTA CATTTCCCAG CAAGCCGCGG GCCGCCCGCG CGCCGCAGTT GACCCATTTC 60
CCGGCCCGTC CCGGGCTCGG CCGGCCCCCG CGCCCAGGCG GCTGCTCCCT GCTGACTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	94.37	0.00e+00	1373.00
IUUC-Apl-003927	Anas platyrhynchos	83.24	0.00e+00	1103.00
IUUC-Aca-004933	Anolis carolinensis	85.21	0.00e+00	1204.00
IUUC-Ame-010997	Astyanax mexicanus	69.98	0.00e+00	1053.00
IUUC-Bta-013077	Bos taurus	93.82	0.00e+00	1367.00
IUUC-Cel-018443	Caenorhabditis elegans	48.50	2.00e-101	363.00
IUUC-Cja-018973	Callithrix jacchus	94.07	0.00e+00	1373.00
IUUC-Cfa-020988	Canis familiaris	90.30	0.00e+00	1235.00
IUUC-Cpo-022496	Cavia porcellus	92.58	0.00e+00	1364.00
IUUC-Csa-023829	Chlorocebus sabaeus	93.22	0.00e+00	1362.00
IUUC-Csv-026143	Ciona savignyi	48.77	0.00e+00	652.00
IUUC-Dre-028560	Danio rerio	64.73	0.00e+00	952.00
IUUC-Dor-030721	Dipodomys ordii	85.04	0.00e+00	1239.00
IUUC-Ete-033074	Echinops telfairi	82.77	1.00e-164	573.00
IUUC-Eca-033760	Equus caballus	92.90	0.00e+00	1264.00
IUUC-Eeu-034953	Erinaceus europaeus	96.61	0.00e+00	747.00
IUUC-Fca-036530	Felis catus	93.44	0.00e+00	1295.00
IUUC-Fal-037353	Ficedula albicollis	87.77	0.00e+00	946.00
IUUC-Gmo-039094	Gadus morhua	68.53	0.00e+00	677.00
IUUC-Gga-040132	Gallus gallus	83.51	0.00e+00	1119.00
IUUC-Gac-041713	Gasterosteus aculeatus	69.90	0.00e+00	1037.00
IUUC-Ggo-045455	Gorilla gorilla	81.18	0.00e+00	1167.00
IUUC-Hsa-046415	Homo sapiens	93.70	0.00e+00	1368.00
IUUC-Lch-050475	Latimeria chalumnae	77.75	0.00e+00	1189.00
IUUC-Loc-051859	Lepisosteus oculatus	73.84	0.00e+00	1126.00
IUUC-Laf-053537	Loxodonta africana	92.71	0.00e+00	1387.00
IUUC-Mcc-055817	Macaca mulatta	92.99	0.00e+00	1361.00
IUUC-Meu-055946	Macropus eugenii	67.16	0.00e+00	889.00
IUUC-Mga-059694	Meleagris gallopavo	83.36	0.00e+00	1097.00
IUUC-Mmr-060768	Microcebus murinus	93.82	0.00e+00	1391.00
IUUC-Mdo-061901	Monodelphis domestica	91.81	0.00e+00	1363.00
IUUC-Mmu-064154	Mus musculus	91.35	0.00e+00	1352.00
IUUC-Mlu-067102	Myotis lucifugus	92.67	0.00e+00	1330.00
IUUC-Ncr-068831	Neurospora crassa	39.60	6.00e-22	99.80
IUUC-Nle-070008	Nomascus leucogenys	93.03	0.00e+00	1274.00
IUUC-Ont-072025	Oreochromis niloticus	69.80	0.00e+00	1039.00
IUUC-Oan-072950	Ornithorhynchus anatinus	86.80	0.00e+00	1148.00
IUUC-Ocu-074316	Oryctolagus cuniculus	92.08	0.00e+00	1251.00
IUUC-Ola-087279	Oryzias latipes	67.56	0.00e+00	1005.00
IUUC-Oga-088284	Otolemur garnettii	93.70	0.00e+00	1385.00
IUUC-Oar-090304	Ovis aries	93.94	0.00e+00	1369.00
IUUC-Ptr-091052	Pan troglodytes	93.82	0.00e+00	1369.00
IUUC-Pan-092270	Papio anubis	87.79	0.00e+00	1322.00
IUUC-Psi-093907	Pelodiscus sinensis	83.29	0.00e+00	1028.00
IUUC-Pfo-097042	Poecilia formosa	69.11	0.00e+00	1111.00
IUUC-Pab-098110	Pongo abelii	93.82	0.00e+00	1369.00
IUUC-Pca-100266	Procavia capensis	79.75	0.00e+00	973.00
IUUC-Pva-102824	Pteropus vampyrus	91.22	0.00e+00	1344.00
IUUC-Pgr-103483	Puccinia graminis	37.46	6.00e-56	213.00
IUUC-Rno-105638	Rattus norvegicus	92.34	0.00e+00	1357.00
IUUC-Sha-107004	Sarcophilus harrisii	84.38	0.00e+00	1103.00
IUUC-Ssc-115280	Sus scrofa	94.07	0.00e+00	1377.00
IUUC-Tgu-116759	Taeniopygia guttata	83.49	0.00e+00	1120.00
IUUC-Tru-117944	Takifugu rubripes	69.44	0.00e+00	1036.00
IUUC-Tsy-119405	Tarsius syrichta	81.81	0.00e+00	1058.00
IUUC-Tni-120571	Tetraodon nigroviridis	69.06	0.00e+00	1044.00
IUUC-Vpa-130294	Vicugna pacos	92.48	0.00e+00	1254.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence