iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ate-010450

Ensembl Protein ID

CADATEAP00000084

UniProt Accession

Q0CVB3; Q0CVB3_ASPTN

Genbank Protein ID

EAU37333.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

CH476596

Gene Name

ATEG_02371

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADATEAG00000084	CADATEAT00000084	CADATEAP00000084

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.00e-60	202.5	19	548

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagg............lGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaeal 81
           YDRQ+rlw + +q++l++a+vllv+ +g            +G+E+lKnLvl Gvg +t+vD + v+ s+l+ +F++++e+ gks+Ae +++ l
   Q: 19   YDRQLRLWAASGQQALEEARVLLVNSDGpwsdqstgvsgvVGVETLKNLVLPGVGGFTIVDPAVVTESDLGLNFFLEEESLGKSRAEETCRLL 111
           *************************8766666666666669**************************************************** PP
   S: 82   kelnpdvnveaheesiteleeeiv.FfkkfdvVvl.aldnrearrkvnrlclnarvpliesgtlGllGqvrviikgl.tecyscsd....dpp 167
           +elnpdv++++ ++sitel +e++ F+ ++++V++ + ++r++ + + ++  ++++p + +++ G++++ +  ++   ++ + ++d    +++
   Q: 112  RELNPDVEGSFRSKSITELLQEDPdFLPQHKLVLIsGPMKRSSLNILCKAAKEYNIPVLYTRSVGFYSTFSLQLPTSfPIVETHPDpettQDL 204
           ********************************9651667777776666777777********************98615555555599999** PP
   S: 168  qktiPfctlketpn..........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafa 246
           ++ +P+++l e  +           ++ +++++ l+ ++l+ +++++ ++++++++ek+e++++v+s++++      een++ea+++++k+++
   Q: 205  RLLNPWPELTEAAArlsnldslddHQHGHVPYILLLLHYLQLWKESHGGSAPSNYKEKTEFRELVRSSARTnnpeGGEENYDEAVAAVLKSLN 297
           ************888999999999***********************************************55555579************** PP
   S: 247  kttins.ikqllksfecdivtkskspfwv................................................................ 274
           ++t  s  ++++++ ec+  +  +++fwv                                                                
   Q: 298  PFTLRSsLREIFEMEECKSPRPASANFWViasavsqfyqkhqvlplpgslpdmkaqsadyvslqniykskarkdveevtdivrqielqigshq 390
           ********************************************************************************************* PP
   S: 275  .........sfcsnaealqvp............ekvekdeevvkasap...lylllralerfekkkgrkpgelsfekddds...avdlvtaaa 340
                     fc+na+ ++v              + + ++  ++++++   + +++++l+ + ++ +   g l  +  dd+     ++ +a+a
   Q: 391  npipekeieLFCKNAAHIKVVhgrdipqidrdaLSLKTSRNSLTMPDSlfpIFVAFQVLDAVITDIQ--EGALPGKSIDDEavwNAKVDQAIA 481
           *******************665555555555442223333334555558776666666666544433..355666666666444344444444 PP
   S: 341  nlra.eslgiep...kldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           +l +  s +i++   +   +++ke+ ++  ++++ +++  gGl+aqE++Kv++ ++ pl+n+ +fd+
   Q: 482  ALTRdDSTDINEetrDSIVEATKELRRTDGGELHNISSLTGGLVAQEALKVITRQYGPLDNTCVFDG 548
           44334667777720223335789******************************************97 PP

Organism

Aspergillus terreus

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MTEAFPSALV GPSSKERKYD RQLRLWAASG QQALEEARVL LVNSDGPWSD QSTGVSGVVG 60
VETLKNLVLP GVGGFTIVDP AVVTESDLGL NFFLEEESLG KSRAEETCRL LRELNPDVEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGAGG CTTTCCCCAG TGCCCTCGTC GGCCCATCGT CGAAGGAGAG AAAGTACGAT 60
CGCCAGCTTC GACTCTGGGC TGCAAGCGGC CAGCAAGCTC TCGAGGAGGC TCGAGTCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	32.25	3.00e-71	260.00
IUUC-Aml-002333	Ailuropoda melanoleuca	34.77	6.00e-85	306.00
IUUC-Atr-002644	Amborella trichopoda	33.52	3.00e-66	244.00
IUUC-Apl-003446	Anas platyrhynchos	33.39	2.00e-75	275.00
IUUC-Aca-004450	Anolis carolinensis	33.10	1.00e-82	298.00
IUUC-Aly-006187	Arabidopsis lyrata	31.39	1.00e-72	265.00
IUUC-Ath-007600	Arabidopsis thaliana	32.24	1.00e-72	265.00
IUUC-Ago-007900	Ashbya gossypii	25.99	1.00e-31	129.00
IUUC-Acl-008333	Aspergillus clavatus	75.09	0.00e+00	853.00
IUUC-Afl-008529	Aspergillus flavus	79.39	0.00e+00	902.00
IUUC-Afu-009071	Aspergillus fumigatus	75.63	0.00e+00	864.00
IUUC-Ani-009443	Aspergillus nidulans	71.86	0.00e+00	787.00
IUUC-Ang-009669	Aspergillus niger	76.55	0.00e+00	884.00
IUUC-Aor-009914	Aspergillus oryzae	78.33	0.00e+00	890.00
IUUC-Ame-011183	Astyanax mexicanus	34.89	2.00e-87	314.00
IUUC-Bgr-012111	Blumeria graminis	44.44	1.00e-117	415.00
IUUC-Bta-012583	Bos taurus	34.89	1.00e-86	311.00
IUUC-Bci-013892	Botrytis cinerea	48.77	7.00e-135	472.00
IUUC-Bdi-014592	Brachypodium distachyon	32.37	3.00e-72	264.00
IUUC-Bol-016401	Brassica oleracea	32.61	1.00e-74	272.00
IUUC-Bra-017506	Brassica rapa	32.19	6.00e-70	256.00
IUUC-Cel-018456	Caenorhabditis elegans	31.27	2.00e-60	224.00
IUUC-Cja-020007	Callithrix jacchus	34.88	5.00e-85	306.00
IUUC-Cfa-020324	Canis familiaris	34.58	2.00e-85	308.00
IUUC-Cpo-022248	Cavia porcellus	31.56	3.00e-44	171.00
IUUC-Csa-023149	Chlorocebus sabaeus	31.61	2.00e-61	228.00
IUUC-Cho-024537	Choloepus hoffmanni	28.48	8.00e-50	189.00
IUUC-Cin-025763	Ciona intestinalis	35.48	7.00e-83	299.00
IUUC-Csv-026113	Ciona savignyi	34.23	5.00e-82	296.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	44.10	3.00e-118	417.00
IUUC-Cne-026884	Cryptococcus neoformans	31.01	8.00e-66	243.00
IUUC-Cme-027210	Cyanidioschyzon merolae	26.96	1.00e-13	69.70
IUUC-Dre-028140	Danio rerio	34.95	5.00e-87	313.00
IUUC-Dno-030033	Dasypus novemcinctus	36.10	2.00e-76	278.00
IUUC-Dor-030513	Dipodomys ordii	49.57	2.00e-24	105.00
IUUC-Dse-031536	Dothistroma septosporum	46.86	2.00e-131	460.00
IUUC-Dme-031683	Drosophila melanogaster	34.77	4.00e-79	286.00
IUUC-Ete-032420	Echinops telfairi	31.05	3.00e-65	240.00
IUUC-Eca-033992	Equus caballus	31.73	1.00e-58	218.00
IUUC-Eeu-034713	Erinaceus europaeus	51.85	2.00e-26	111.00
IUUC-Fca-036548	Felis catus	34.53	2.00e-85	307.00
IUUC-Fal-037600	Ficedula albicollis	32.48	3.00e-73	267.00
IUUC-Fox-038037	Fusarium oxysporum	44.66	3.00e-126	443.00
IUUC-Fso-038387	Fusarium solani	44.72	2.00e-131	460.00
IUUC-Gmo-038562	Gadus morhua	32.92	7.00e-85	306.00
IUUC-Ggr-040005	Gaeumannomyces graminis	46.74	2.00e-136	477.00
IUUC-Gga-041129	Gallus gallus	34.12	2.00e-80	291.00
IUUC-Gac-042558	Gasterosteus aculeatus	33.57	5.00e-83	299.00
IUUC-Gma-043610	Glycine max	33.82	2.00e-71	261.00
IUUC-Ggo-045611	Gorilla gorilla	34.88	1.00e-84	305.00
IUUC-Hsa-046563	Homo sapiens	35.06	1.00e-86	311.00
IUUC-Hvu-047790	Hordeum vulgare	29.24	8.00e-41	159.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	35.07	2.00e-85	308.00
IUUC-Kpa-049309	Komagataella pastoris	33.70	2.00e-72	264.00
IUUC-Lch-050038	Latimeria chalumnae	34.85	1.00e-78	285.00
IUUC-Lpe-051535	Leersia perrieri	30.15	1.00e-53	202.00
IUUC-Loc-051917	Lepisosteus oculatus	31.78	2.00e-75	274.00
IUUC-Lma-053112	Leptosphaeria maculans	49.91	2.00e-152	530.00
IUUC-Laf-053690	Loxodonta africana	35.43	4.00e-87	313.00
IUUC-Mcc-055117	Macaca mulatta	33.93	8.00e-81	292.00
IUUC-Meu-056761	Macropus eugenii	28.16	2.00e-55	207.00
IUUC-Mor-057230	Magnaporthe oryzae	46.35	5.00e-136	476.00
IUUC-Mpo-057514	Magnaporthe poae	47.37	4.00e-130	456.00
IUUC-Mtr-058551	Medicago truncatula	31.97	1.00e-69	255.00
IUUC-Mla-059183	Melampsora laricipopulina	33.16	1.00e-78	285.00
IUUC-Mga-060144	Meleagris gallopavo	32.91	2.00e-76	278.00
IUUC-Mvi-060221	Microbotryum violaceum	34.35	3.00e-77	281.00
IUUC-Mmr-061325	Microcebus murinus	33.63	8.00e-80	289.00
IUUC-Mdo-062532	Monodelphis domestica	34.83	3.00e-86	310.00
IUUC-Mmu-063956	Mus musculus	34.71	3.00e-86	310.00
IUUC-Mac-064521	Musa acuminata	31.18	4.00e-69	253.00
IUUC-Mpu-066716	Mustela putorius furo	34.62	1.00e-76	278.00
IUUC-Mlu-067459	Myotis lucifugus	35.02	5.00e-88	316.00
IUUC-Nfi-068245	Neosartorya fischeri	75.09	0.00e+00	862.00
IUUC-Ncr-068910	Neurospora crassa	48.08	1.00e-143	501.00
IUUC-Nle-070034	Nomascus leucogenys	33.15	1.00e-76	278.00
IUUC-Opr-070552	Ochotona princeps	31.93	7.00e-64	236.00
IUUC-Ont-071426	Oreochromis niloticus	34.59	8.00e-88	315.00
IUUC-Oan-073389	Ornithorhynchus anatinus	32.82	6.00e-55	206.00
IUUC-Ocu-074911	Oryctolagus cuniculus	34.53	3.00e-85	307.00
IUUC-Oba-075437	Oryza barthii	31.40	1.00e-60	225.00
IUUC-Obr-076684	Oryza brachyantha	31.69	1.00e-56	212.00
IUUC-Ogl-077170	Oryza glaberrima	31.40	1.00e-60	225.00
IUUC-Ogu-078844	Oryza glumaepatula	31.26	3.00e-54	204.00
IUUC-Oin-079105	Oryza indica	31.40	2.00e-60	224.00
IUUC-Olo-080943	Oryza longistaminata	29.96	2.00e-47	181.00
IUUC-Oni-082891	Oryza nivara	28.68	4.00e-54	203.00
IUUC-Opu-083457	Oryza punctata	31.40	2.00e-59	221.00
IUUC-Oru-084960	Oryza rufipogon	29.96	1.00e-47	182.00
IUUC-Osa-085358	Oryza sativa	31.58	4.00e-60	223.00
IUUC-Ola-086420	Oryzias latipes	31.41	9.00e-50	188.00
IUUC-Olu-087625	Ostreococcus lucimarinus	26.21	8.00e-43	166.00
IUUC-Oga-088810	Otolemur garnettii	34.94	9.00e-87	312.00
IUUC-Oar-089196	Ovis aries	34.70	9.00e-85	305.00
IUUC-Ptr-090617	Pan troglodytes	34.88	8.00e-86	309.00
IUUC-Pan-092761	Papio anubis	35.07	1.00e-86	311.00
IUUC-Psi-093191	Pelodiscus sinensis	33.52	8.00e-78	282.00
IUUC-Pma-094380	Petromyzon marinus	35.38	1.00e-76	278.00
IUUC-Pno-095084	Phaeosphaeria nodorum	46.75	2.00e-129	455.00
IUUC-Ppa-095798	Physcomitrella patens	31.28	1.00e-71	262.00
IUUC-Pfo-096467	Poecilia formosa	34.35	6.00e-85	306.00
IUUC-Pab-098255	Pongo abelii	36.88	6.00e-77	279.00
IUUC-Pop-099722	Populus trichocarpa	31.78	3.00e-74	270.00
IUUC-Pca-100807	Procavia capensis	38.66	4.00e-29	120.00
IUUC-Ppe-101280	Prunus persica	33.27	2.00e-74	271.00
IUUC-Pva-102333	Pteropus vampyrus	33.87	4.00e-79	287.00
IUUC-Pgr-103401	Puccinia graminis	29.57	6.00e-66	243.00
IUUC-Ptt-103889	Puccinia triticina	28.62	1.00e-59	222.00
IUUC-Pte-104355	Pyrenophora teres	50.69	1.00e-155	541.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	50.43	2.00e-154	537.00
IUUC-Rno-105810	Rattus norvegicus	34.05	3.00e-84	303.00
IUUC-Sce-106397	Saccharomyces cerevisiae	23.74	5.00e-24	103.00
IUUC-Sha-106770	Sarcophilus harrisii	40.69	1.00e-50	191.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	31.01	5.00e-72	263.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.97	4.00e-75	273.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	48.06	1.00e-134	471.00
IUUC-Smo-109296	Selaginella moellendorffii	33.15	2.00e-77	281.00
IUUC-Sit-110157	Setaria italica	32.12	4.00e-72	263.00
IUUC-Sly-111105	Solanum lycopersicum	32.08	3.00e-73	267.00
IUUC-Stu-112469	Solanum tuberosum	32.26	4.00e-75	273.00
IUUC-Sar-113083	Sorex araneus	25.51	1.00e-44	172.00
IUUC-Sbi-113813	Sorghum bicolor	31.51	4.00e-70	257.00
IUUC-Sre-115058	Sporisorium reilianum	36.43	8.00e-66	243.00
IUUC-Tgu-116772	Taeniopygia guttata	33.33	1.00e-74	271.00
IUUC-Tru-118686	Takifugu rubripes	33.87	9.00e-88	315.00
IUUC-Tsy-119111	Tarsius syrichta	36.18	4.00e-40	157.00
IUUC-Tni-120231	Tetraodon nigroviridis	31.43	2.00e-73	267.00
IUUC-Tca-121491	Theobroma cacao	34.12	1.00e-70	258.00
IUUC-Tre-122103	Trichoderma reesei	46.75	2.00e-132	464.00
IUUC-Tvi-122672	Trichoderma virens	45.10	1.00e-129	454.00
IUUC-Tae-125684	Triticum aestivum	32.07	8.00e-72	262.00
IUUC-Tur-126487	Triticum urartu	31.39	1.00e-66	245.00
IUUC-Tme-127097	Tuber melanosporum	37.66	6.00e-92	329.00
IUUC-Ttr-128465	Tursiops truncatus	31.74	2.00e-69	254.00
IUUC-Uma-129645	Ustilago maydis	32.05	2.00e-75	275.00
IUUC-Vda-129989	Verticillium dahliae	40.71	8.00e-96	342.00
IUUC-Vpa-130529	Vicugna pacos	32.74	3.00e-74	271.00
IUUC-Vvi-131059	Vitis vinifera	31.75	2.00e-71	261.00
IUUC-Xtr-132002	Xenopus tropicalis	35.79	6.00e-89	319.00
IUUC-Xma-133930	Xiphophorus maculatus	34.29	8.00e-83	299.00
IUUC-Yli-134505	Yarrowia lipolytica	34.36	1.00e-78	285.00
IUUC-Zma-135895	Zea mays	31.33	1.00e-69	255.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence