iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003966

Ensembl Protein ID

ENSAPLP00000014969.1

UniProt Accession

U3J642; U3J642_ANAPL

Genbank Protein ID

ENSAPLP00000014969

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01155801

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000015091.1	ENSAPLT00000015756.1	ENSAPLP00000014969.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	54.52	0.00e+00	927.00	IUUC-Hsa-046671

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LFDPFFPEGY TGLAEAIENW DFSKLEKLEL HRQLLKRIEA TMLEVDPVAL IPYISTCLID 60
RECEEIQQIS ENRSKAAGIT KLIECLCRSD KEHWPKSLQL ALDTTGYYRA SELWDIREVF 120

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Nucleotide Sequence
(Fasta)

CTCTTTGACC CTTTTTTTCC TGAAGGTTAC ACAGGACTGG CAGAAGCAAT TGAGAACTGG 60
GACTTCAGCA AACTGGAAAA ACTGGAGTTA CACAGACAGC TGTTGAAGCG GATAGAGGCA 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	52.31	0.00e+00	860.00
IUUC-Aca-004499	Anolis carolinensis	48.31	0.00e+00	764.00
IUUC-Ame-011950	Astyanax mexicanus	42.48	0.00e+00	649.00
IUUC-Bta-012489	Bos taurus	53.12	0.00e+00	887.00
IUUC-Cel-018230	Caenorhabditis elegans	28.48	2.00e-67	250.00
IUUC-Cja-018716	Callithrix jacchus	53.94	0.00e+00	867.00
IUUC-Cfa-020269	Canis familiaris	51.93	0.00e+00	860.00
IUUC-Cpo-022507	Cavia porcellus	52.54	0.00e+00	865.00
IUUC-Csa-024209	Chlorocebus sabaeus	53.23	0.00e+00	887.00
IUUC-Cho-025104	Choloepus hoffmanni	48.25	0.00e+00	749.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	23.39	3.00e-28	120.00
IUUC-Dno-028954	Dasypus novemcinctus	52.60	0.00e+00	858.00
IUUC-Eca-034039	Equus caballus	54.53	0.00e+00	897.00
IUUC-Eeu-035009	Erinaceus europaeus	51.59	0.00e+00	669.00
IUUC-Fca-036169	Felis catus	52.09	0.00e+00	897.00
IUUC-Fal-037579	Ficedula albicollis	77.14	0.00e+00	1328.00
IUUC-Ggo-045318	Gorilla gorilla	52.74	0.00e+00	867.00
IUUC-Hsa-046671	Homo sapiens	53.69	0.00e+00	879.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	52.04	0.00e+00	860.00
IUUC-Lch-050461	Latimeria chalumnae	52.58	0.00e+00	900.00
IUUC-Loc-052582	Lepisosteus oculatus	49.71	0.00e+00	801.00
IUUC-Laf-054324	Loxodonta africana	52.50	0.00e+00	844.00
IUUC-Mcc-055390	Macaca mulatta	53.00	0.00e+00	881.00
IUUC-Meu-056365	Macropus eugenii	54.49	2.00e-98	353.00
IUUC-Mmr-061407	Microcebus murinus	53.36	0.00e+00	919.00
IUUC-Mmu-063939	Mus musculus	52.84	0.00e+00	883.00
IUUC-Mpu-066226	Mustela putorius furo	51.84	0.00e+00	849.00
IUUC-Mlu-068092	Myotis lucifugus	53.18	0.00e+00	867.00
IUUC-Opr-070246	Ochotona princeps	46.65	2.00e-122	433.00
IUUC-Oan-072742	Ornithorhynchus anatinus	54.53	0.00e+00	838.00
IUUC-Ocu-073959	Oryctolagus cuniculus	51.57	0.00e+00	848.00
IUUC-Oga-089173	Otolemur garnettii	52.80	0.00e+00	872.00
IUUC-Oar-089369	Ovis aries	53.24	0.00e+00	868.00
IUUC-Ptr-091032	Pan troglodytes	53.69	0.00e+00	879.00
IUUC-Pan-092383	Papio anubis	53.29	0.00e+00	887.00
IUUC-Psi-093432	Pelodiscus sinensis	63.04	0.00e+00	1118.00
IUUC-Pma-094367	Petromyzon marinus	40.20	5.00e-111	394.00
IUUC-Pab-098416	Pongo abelii	53.15	0.00e+00	867.00
IUUC-Pca-101006	Procavia capensis	54.94	2.00e-126	446.00
IUUC-Pva-102966	Pteropus vampyrus	54.10	0.00e+00	895.00
IUUC-Rno-105059	Rattus norvegicus	51.04	5.00e-143	501.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	26.17	2.00e-06	48.90
IUUC-Sar-113202	Sorex araneus	50.22	0.00e+00	635.00
IUUC-Ssc-116120	Sus scrofa	51.45	0.00e+00	851.00
IUUC-Tgu-117314	Taeniopygia guttata	76.69	0.00e+00	1313.00
IUUC-Tsy-119453	Tarsius syrichta	54.41	9.00e-164	570.00
IUUC-Tre-122194	Trichoderma reesei	24.53	1.00e-22	102.00
IUUC-Ttr-128421	Tursiops truncatus	49.62	0.00e+00	739.00
IUUC-Vpa-130602	Vicugna pacos	50.87	0.00e+00	854.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence