iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028617

Ensembl Protein ID

ENSDARP00000128798.1

UniProt Accession

X1WEZ5; X1WEZ5_DANRE

Genbank Protein ID

ENSDARP00000128798

Protein Name

Si:dkey-37f18.2

Genbank Nucleotide ID

BX323824

Gene Name

OTUD7A; si:dkey-37f18.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000045556.7	ENSDART00000156751.2	ENSDARP00000128798.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	3.80e-38	131.9	180	361

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++ l+ ++++ +++++ k+++++++++++k           e+e++++ kl+++e    
   Q: 180  LPLATTGDGNCLLHAASLGMWGFHDRDLvLRKSLYAMMKSGAEREALKRRWRWQQTQQNKesglvyteeewEREWNELLKLASSEprth 268
           6899*********************************************************************************8877 PP
   S: 75   .ak.g.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYda 134
            +k g                 ee+h+f+La++L+rpi+v+++++l++         ++gg +lpl++p+++ +++p+vL+Y+++H++a
   Q: 269  fSKnGnssggvdnsedpvyeslEEFHVFVLAHVLRRPIVVIADTMLRDsggeafapiPFGGLYLPLEVPPNRcHCSPLVLAYDQAHFSA 357
           7444477889******************************************************************************* PP
   S: 135  Lval 138
           Lv++
   Q: 358  LVSM 361
           *986 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MTLDMDAVLS DFVRSTGAEP GLARDLLEGK NWDLSAALND YEQLRQVHTA NLPHVFNEGR 60
YYKQTERSSS SSTPQHSSRP EQKQPEDNTQ EKRLSRGISH ASSAIMSLAR LQVSGDCARE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCTATATA CAACACTTTA TTTTGAATGT GATTAATATT TGTCGAGCGC CAGCTTTGGG 60
TATTCTGTAA TTAAACCATA TTAGTGATTG TATTACTCAT CAGAACTGAT CTTCTGTACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

SMART

SM00259--ZnF_A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050727--P:regulation of inflammatory response
GO:0045088--P:regulation of innate immune response

KEGG

dre:559455

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001551	Ailuropoda melanoleuca	80.66	0.00e+00	891.00
IUUC-Apl-003825	Anas platyrhynchos	69.90	0.00e+00	1184.00
IUUC-Aca-004392	Anolis carolinensis	73.87	0.00e+00	1253.00
IUUC-Ame-011052	Astyanax mexicanus	88.64	0.00e+00	1424.00
IUUC-Bta-013296	Bos taurus	67.14	0.00e+00	1007.00
IUUC-Cja-019141	Callithrix jacchus	78.60	0.00e+00	905.00
IUUC-Cfa-020447	Canis familiaris	80.75	0.00e+00	936.00
IUUC-Cpo-022059	Cavia porcellus	87.84	0.00e+00	833.00
IUUC-Csa-023263	Chlorocebus sabaeus	81.76	0.00e+00	950.00
IUUC-Cho-024611	Choloepus hoffmanni	80.06	4.00e-156	545.00
IUUC-Csv-026177	Ciona savignyi	29.76	9.00e-03	33.50
IUUC-Dno-029121	Dasypus novemcinctus	78.98	0.00e+00	936.00
IUUC-Ete-033068	Echinops telfairi	73.57	0.00e+00	855.00
IUUC-Eca-034413	Equus caballus	81.11	0.00e+00	902.00
IUUC-Eeu-034670	Erinaceus europaeus	52.72	0.00e+00	791.00
IUUC-Fca-036487	Felis catus	78.88	0.00e+00	865.00
IUUC-Fal-037145	Ficedula albicollis	74.65	0.00e+00	1240.00
IUUC-Gmo-038786	Gadus morhua	70.68	0.00e+00	1152.00
IUUC-Gga-040512	Gallus gallus	72.60	0.00e+00	1209.00
IUUC-Gac-041599	Gasterosteus aculeatus	79.83	0.00e+00	1276.00
IUUC-Ggo-044819	Gorilla gorilla	67.29	0.00e+00	1004.00
IUUC-Hsa-046781	Homo sapiens	67.63	0.00e+00	1040.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	53.64	0.00e+00	816.00
IUUC-Lch-050666	Latimeria chalumnae	76.67	0.00e+00	1240.00
IUUC-Loc-052841	Lepisosteus oculatus	79.96	0.00e+00	1360.00
IUUC-Laf-053437	Loxodonta africana	77.28	0.00e+00	929.00
IUUC-Mcc-055353	Macaca mulatta	67.59	0.00e+00	1036.00
IUUC-Meu-056477	Macropus eugenii	59.74	0.00e+00	646.00
IUUC-Mga-059741	Meleagris gallopavo	70.83	0.00e+00	1161.00
IUUC-Mmr-061437	Microcebus murinus	80.48	0.00e+00	984.00
IUUC-Mdo-061907	Monodelphis domestica	77.86	0.00e+00	1243.00
IUUC-Mmu-064074	Mus musculus	80.51	0.00e+00	944.00
IUUC-Mpu-066004	Mustela putorius furo	79.81	0.00e+00	886.00
IUUC-Mlu-068039	Myotis lucifugus	63.41	0.00e+00	777.00
IUUC-Nle-069182	Nomascus leucogenys	81.67	0.00e+00	952.00
IUUC-Opr-070701	Ochotona princeps	72.54	0.00e+00	759.00
IUUC-Ont-072431	Oreochromis niloticus	91.57	0.00e+00	900.00
IUUC-Oan-073235	Ornithorhynchus anatinus	61.41	0.00e+00	940.00
IUUC-Ocu-073935	Oryctolagus cuniculus	80.75	0.00e+00	875.00
IUUC-Ola-087026	Oryzias latipes	81.75	0.00e+00	1390.00
IUUC-Oga-088249	Otolemur garnettii	80.18	0.00e+00	986.00
IUUC-Oar-089476	Ovis aries	68.30	0.00e+00	1066.00
IUUC-Ptr-090548	Pan troglodytes	80.70	0.00e+00	861.00
IUUC-Pan-092616	Papio anubis	80.42	0.00e+00	924.00
IUUC-Psi-093126	Pelodiscus sinensis	75.16	0.00e+00	1242.00
IUUC-Pfo-096785	Poecilia formosa	81.61	0.00e+00	1365.00
IUUC-Pab-098336	Pongo abelii	81.37	0.00e+00	949.00
IUUC-Pca-100206	Procavia capensis	73.75	0.00e+00	783.00
IUUC-Pva-102136	Pteropus vampyrus	52.09	0.00e+00	776.00
IUUC-Rno-105483	Rattus norvegicus	81.62	0.00e+00	691.00
IUUC-Sha-106617	Sarcophilus harrisii	79.54	0.00e+00	849.00
IUUC-Spo-108191	Schizosaccharomyces pombe	38.46	7.90e+00	25.80
IUUC-Sar-113562	Sorex araneus	55.98	1.00e-169	590.00
IUUC-Ssc-115415	Sus scrofa	80.00	0.00e+00	882.00
IUUC-Tgu-117218	Taeniopygia guttata	81.34	0.00e+00	989.00
IUUC-Tru-118720	Takifugu rubripes	87.84	0.00e+00	851.00
IUUC-Tsy-119343	Tarsius syrichta	61.34	0.00e+00	734.00
IUUC-Tni-120795	Tetraodon nigroviridis	83.45	0.00e+00	987.00
IUUC-Ttr-128692	Tursiops truncatus	50.85	0.00e+00	737.00
IUUC-Xtr-132158	Xenopus tropicalis	74.73	0.00e+00	1252.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence