iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062951

UUCD1 version

UUC-MoD-00338

Ensembl Protein ID

ENSMODP00000012843.2

UniProt Accession

F6W659; F6W659_MONDO

Protein Name

Uncharacterized protein

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010250.3	ENSMODT00000013078.3	ENSMODP00000012843.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-08	35.1	12	53
UBD/SH3	1.30e-30	105.3	386	442

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     +++ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRI----FKARKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           + + +l++y+a   +eL l+kG+ ++v+   +  egWlkgv+  +g+ G+fP+n+v+ +
   Q: 386  NMFVALHSYSAHGPEELDLQKGEGIRVL--GKYHEGWLKGVSLVTGRVGIFPHNYVVPI 442
           6789************************..78889*********************876 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MDDLALLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRI FKARKELRCP ECRTLVFCSI 60
EELPANLLLV RLLDGVRSGQ SMVRVGSIRR PGVLTSQDPS RKTRTDPRGS QPSPYRLTPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGATT TGGCGTTACT TGATCTACTG GAGTGTCCCG TGTGTTTTGA AAAGCTAGAT 60
GTCACAGCCA AAGTCCTCCC CTGCCAGCAC ACCTTTTGTA AACCATGTCT ACAGAGGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	73.19	0.00e+00	932.00
IUUC-Apl-003443	Anas platyrhynchos	58.72	0.00e+00	634.00
IUUC-Aca-004632	Anolis carolinensis	56.80	0.00e+00	644.00
IUUC-Bta-013400	Bos taurus	74.19	0.00e+00	900.00
IUUC-Cel-018180	Caenorhabditis elegans	26.30	4.00e-21	97.10
IUUC-Cja-019686	Callithrix jacchus	64.63	0.00e+00	791.00
IUUC-Cfa-020893	Canis familiaris	74.25	0.00e+00	932.00
IUUC-Cpo-021638	Cavia porcellus	70.61	0.00e+00	875.00
IUUC-Csa-023846	Chlorocebus sabaeus	73.11	0.00e+00	954.00
IUUC-Cho-024609	Choloepus hoffmanni	76.38	3.00e-154	538.00
IUUC-Dno-028940	Dasypus novemcinctus	71.66	0.00e+00	916.00
IUUC-Dor-030491	Dipodomys ordii	86.19	2.00e-107	383.00
IUUC-Dse-031414	Dothistroma septosporum	31.82	6.00e-07	50.10
IUUC-Ete-032513	Echinops telfairi	73.92	0.00e+00	926.00
IUUC-Eca-034241	Equus caballus	74.49	0.00e+00	982.00
IUUC-Eeu-034636	Erinaceus europaeus	66.76	0.00e+00	778.00
IUUC-Fca-035862	Felis catus	72.47	0.00e+00	934.00
IUUC-Gga-040748	Gallus gallus	52.85	5.00e-151	528.00
IUUC-Ggo-045267	Gorilla gorilla	72.98	0.00e+00	920.00
IUUC-Hsa-045761	Homo sapiens	72.84	0.00e+00	915.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	71.88	0.00e+00	882.00
IUUC-Lch-050498	Latimeria chalumnae	44.23	5.00e-126	445.00
IUUC-Laf-054061	Loxodonta africana	63.77	0.00e+00	649.00
IUUC-Mcc-054746	Macaca mulatta	72.65	0.00e+00	915.00
IUUC-Meu-056390	Macropus eugenii	74.08	1.00e-125	444.00
IUUC-Mmr-061390	Microcebus murinus	69.12	0.00e+00	738.00
IUUC-Mmu-063840	Mus musculus	69.27	0.00e+00	886.00
IUUC-Mpu-065840	Mustela putorius furo	72.60	0.00e+00	954.00
IUUC-Mlu-067378	Myotis lucifugus	71.64	0.00e+00	886.00
IUUC-Nle-069535	Nomascus leucogenys	70.37	0.00e+00	873.00
IUUC-Opr-070739	Ochotona princeps	70.51	0.00e+00	884.00
IUUC-Oan-073468	Ornithorhynchus anatinus	68.49	0.00e+00	863.00
IUUC-Ocu-074343	Oryctolagus cuniculus	69.93	0.00e+00	851.00
IUUC-Oga-088276	Otolemur garnettii	65.25	0.00e+00	823.00
IUUC-Oar-090315	Ovis aries	72.15	0.00e+00	893.00
IUUC-Ptr-091119	Pan troglodytes	72.84	0.00e+00	917.00
IUUC-Pan-092158	Papio anubis	78.97	0.00e+00	736.00
IUUC-Psi-092959	Pelodiscus sinensis	63.87	0.00e+00	776.00
IUUC-Pab-097675	Pongo abelii	72.84	0.00e+00	920.00
IUUC-Pca-101021	Procavia capensis	64.84	0.00e+00	816.00
IUUC-Pva-102619	Pteropus vampyrus	73.90	0.00e+00	919.00
IUUC-Rno-105918	Rattus norvegicus	69.55	0.00e+00	885.00
IUUC-Sha-107391	Sarcophilus harrisii	80.22	0.00e+00	1114.00
IUUC-Sja-107661	Schizosaccharomyces japonicus	43.86	4.00e-09	55.80
IUUC-Sar-113148	Sorex araneus	74.31	4.00e-171	594.00
IUUC-Ssc-116219	Sus scrofa	64.02	2.00e-100	359.00
IUUC-Tgu-116584	Taeniopygia guttata	64.90	2.00e-76	279.00
IUUC-Tsy-118968	Tarsius syrichta	72.41	4.00e-143	501.00
IUUC-Tbe-128007	Tupaia belangeri	78.49	0.00e+00	718.00
IUUC-Ttr-128499	Tursiops truncatus	72.84	0.00e+00	951.00
IUUC-Vpa-130075	Vicugna pacos	91.80	8.00e-69	254.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence