iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091426

UUCD1 version

UUC-PaT-00232

Ensembl Protein ID

ENSPTRP00000010018.4

UniProt Accession

H2Q7L3; H2Q7L3_PANTR

Genbank Protein ID

JAA09725.1; JAA21416.1; JAA25804.1; JAA35161.1

Protein Name

WD repeat and FYVE domain containing 2

Genbank Nucleotide ID

AACZ03092593; GABF01000729; GABD01007296; GABE01009578

Gene Name

WDFY2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000005892.4	ENSPTRT00000010822.4	ENSPTRP00000010018.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-17	63.5	197	227

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt++vt+l++ +  + l sGs D+++ +WD
   Q: 197  GHTGGVTALCWdPVqRVLFSGSSDHSVIMWD 227
           8**********855689************** PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAAEIQPKPL TRKPILLQRM EGSQEVVNMA VIVPKEEGVI SVSEDRTVRV WLKRDSGQYW 60
PSIYHAMPSP CSCMSFNPET RRLSIGLDNG TISEFILSED YNKMTPVKNY QAHQSRVTMI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCTTCACC ACCCTCCCGG AAGTGGAGCC GCCCTCGCGC CCACCAGCGG CTACCCCCTG 60
CGGCAGGCCC CGCCCACACA GGCTCCGCCC CCCGGCGCTC CGCCCCCTCC TCTGGTAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00064--FYVE
SM00320--WD40

Gene Ontology

GO:0005769--C:early endosome
GO:0046872--F:metal ion binding
GO:0045600--P:positive regulation of fat cell differentiation
GO:0001934--P:positive regulation of protein phosphorylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002074	Ailuropoda melanoleuca	98.50	0.00e+00	825.00
IUUC-Apl-003892	Anas platyrhynchos	87.01	0.00e+00	652.00
IUUC-Aca-004902	Anolis carolinensis	87.53	0.00e+00	749.00
IUUC-Ame-010837	Astyanax mexicanus	83.50	0.00e+00	729.00
IUUC-Cel-018382	Caenorhabditis elegans	42.09	5.00e-100	357.00
IUUC-Cja-019949	Callithrix jacchus	98.75	0.00e+00	827.00
IUUC-Cfa-020057	Canis familiaris	97.18	0.00e+00	726.00
IUUC-Cpo-022446	Cavia porcellus	99.00	0.00e+00	831.00
IUUC-Csa-023138	Chlorocebus sabaeus	99.75	0.00e+00	833.00
IUUC-Cho-024545	Choloepus hoffmanni	83.38	0.00e+00	671.00
IUUC-Cin-025573	Ciona intestinalis	53.37	2.00e-137	482.00
IUUC-Csv-026091	Ciona savignyi	53.25	2.00e-138	484.00
IUUC-Dre-027501	Danio rerio	84.25	0.00e+00	736.00
IUUC-Dno-029611	Dasypus novemcinctus	96.50	0.00e+00	811.00
IUUC-Dor-030240	Dipodomys ordii	84.65	0.00e+00	665.00
IUUC-Dme-031869	Drosophila melanogaster	50.49	7.00e-133	466.00
IUUC-Ete-032680	Echinops telfairi	72.75	2.00e-162	565.00
IUUC-Eca-033811	Equus caballus	99.25	0.00e+00	830.00
IUUC-Eeu-034637	Erinaceus europaeus	86.00	0.00e+00	706.00
IUUC-Fca-036536	Felis catus	99.40	0.00e+00	696.00
IUUC-Fal-037221	Ficedula albicollis	94.65	0.00e+00	716.00
IUUC-Gmo-039257	Gadus morhua	80.75	0.00e+00	706.00
IUUC-Gga-040902	Gallus gallus	93.50	0.00e+00	791.00
IUUC-Gac-042268	Gasterosteus aculeatus	78.75	0.00e+00	689.00
IUUC-Ggo-044590	Gorilla gorilla	99.75	0.00e+00	833.00
IUUC-Hsa-045692	Homo sapiens	99.50	0.00e+00	834.00
IUUC-Itr-049053	Ictidomys tridecemlineatus	99.25	0.00e+00	832.00
IUUC-Loc-052370	Lepisosteus oculatus	84.96	0.00e+00	746.00
IUUC-Laf-054594	Loxodonta africana	98.50	0.00e+00	823.00
IUUC-Mcc-055882	Macaca mulatta	99.37	0.00e+00	664.00
IUUC-Meu-056323	Macropus eugenii	92.84	0.00e+00	770.00
IUUC-Mga-060043	Meleagris gallopavo	94.08	0.00e+00	707.00
IUUC-Mmr-060574	Microcebus murinus	99.69	0.00e+00	665.00
IUUC-Mdo-062455	Monodelphis domestica	93.25	0.00e+00	791.00
IUUC-Mmu-064270	Mus musculus	98.75	0.00e+00	829.00
IUUC-Mpu-066482	Mustela putorius furo	98.48	0.00e+00	672.00
IUUC-Mlu-067061	Myotis lucifugus	93.54	1.00e-165	575.00
IUUC-Nle-069796	Nomascus leucogenys	99.75	0.00e+00	835.00
IUUC-Opr-071092	Ochotona princeps	98.50	0.00e+00	825.00
IUUC-Ont-072372	Oreochromis niloticus	82.50	0.00e+00	716.00
IUUC-Oan-073463	Ornithorhynchus anatinus	91.62	0.00e+00	654.00
IUUC-Ocu-074804	Oryctolagus cuniculus	99.75	0.00e+00	834.00
IUUC-Oga-088615	Otolemur garnettii	90.03	2.00e-176	611.00
IUUC-Oar-089827	Ovis aries	97.98	0.00e+00	813.00
IUUC-Pan-092239	Papio anubis	99.66	5.00e-179	619.00
IUUC-Psi-093305	Pelodiscus sinensis	93.44	0.00e+00	754.00
IUUC-Pfo-096834	Poecilia formosa	81.25	0.00e+00	711.00
IUUC-Pab-098398	Pongo abelii	100.00	0.00e+00	836.00
IUUC-Pca-100650	Procavia capensis	72.50	5.00e-164	570.00
IUUC-Pva-102773	Pteropus vampyrus	99.00	0.00e+00	829.00
IUUC-Rno-104983	Rattus norvegicus	98.25	0.00e+00	827.00
IUUC-Sha-107407	Sarcophilus harrisii	94.25	0.00e+00	797.00
IUUC-Sar-113400	Sorex araneus	76.23	1.00e-114	405.00
IUUC-Tgu-116478	Taeniopygia guttata	93.25	0.00e+00	791.00
IUUC-Tru-118438	Takifugu rubripes	81.50	0.00e+00	712.00
IUUC-Tsy-119319	Tarsius syrichta	97.75	0.00e+00	815.00
IUUC-Tni-120051	Tetraodon nigroviridis	79.50	0.00e+00	697.00
IUUC-Ttr-129137	Tursiops truncatus	93.00	0.00e+00	768.00
IUUC-Vpa-130398	Vicugna pacos	86.38	2.00e-176	611.00
IUUC-Xtr-132445	Xenopus tropicalis	86.00	0.00e+00	753.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence