iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000015233.3	ENSMMUT00000058208.1	ENSMMUP00000048076.1
ENSMMUG00000015233.3	ENSMMUT00000021356.3	ENSMMUP00000019972.3
ENSMMUG00000015233.3	ENSMMUT00000021355.3	ENSMMUP00000019971.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.40e-21	76.8	347	393

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 347  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 393
           8********988.6*******************.*******7.******5 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MEPATALHPG PRPALPLGGP GPLGEFLPPP ECPVFEPSWE EFADPFAFIH KIRPIAEQTG 60
ICKVRPPPDW QPPFACDVDK LHFTPRIQRL NELEAQTRVK LNFLDQIAKY WELQGSTLKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTCCGTTA AAGGATACCC CGTTGGGTAT CTCTACCTGT TTGTACCAGA GACACCTCAA 60
ATTCAAAATG TCCAGAAATG AGCACAGCAC CTTCTTCCCT TGAATAACTC GCCTTGTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.35	2.00e-101	364.00
IUUC-Aml-001963	Ailuropoda melanoleuca	94.38	0.00e+00	2781.00
IUUC-Apl-003770	Anas platyrhynchos	83.46	0.00e+00	2155.00
IUUC-Aca-004867	Anolis carolinensis	80.22	0.00e+00	2488.00
IUUC-Ath-007218	Arabidopsis thaliana	35.56	4.00e-09	58.50
IUUC-Acl-008162	Aspergillus clavatus	31.61	1.00e-114	408.00
IUUC-Ame-010620	Astyanax mexicanus	61.28	0.00e+00	1906.00
IUUC-Bta-012733	Bos taurus	89.61	0.00e+00	2655.00
IUUC-Bol-015336	Brassica oleracea	36.45	3.00e-14	75.90
IUUC-Cja-019050	Callithrix jacchus	96.32	0.00e+00	2928.00
IUUC-Cfa-021015	Canis familiaris	94.44	0.00e+00	2774.00
IUUC-Cpo-022340	Cavia porcellus	94.18	0.00e+00	2734.00
IUUC-Csa-023441	Chlorocebus sabaeus	97.47	0.00e+00	2917.00
IUUC-Cho-024823	Choloepus hoffmanni	94.13	0.00e+00	1695.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	29.97	4.00e-107	383.00
IUUC-Cne-026851	Cryptococcus neoformans	28.93	2.00e-113	404.00
IUUC-Dre-027707	Danio rerio	60.19	0.00e+00	1829.00
IUUC-Dno-028978	Dasypus novemcinctus	94.44	0.00e+00	2843.00
IUUC-Dor-030854	Dipodomys ordii	86.67	0.00e+00	1926.00
IUUC-Ete-032760	Echinops telfairi	91.20	0.00e+00	1858.00
IUUC-Eca-034370	Equus caballus	94.71	0.00e+00	2709.00
IUUC-Eeu-035012	Erinaceus europaeus	81.20	0.00e+00	1750.00
IUUC-Fca-035494	Felis catus	95.18	0.00e+00	2778.00
IUUC-Fal-037631	Ficedula albicollis	81.07	0.00e+00	2395.00
IUUC-Gmo-039522	Gadus morhua	58.00	0.00e+00	1724.00
IUUC-Gga-040802	Gallus gallus	81.91	0.00e+00	2443.00
IUUC-Gac-041563	Gasterosteus aculeatus	61.26	0.00e+00	1848.00
IUUC-Gma-042675	Glycine max	32.34	4.00e-101	363.00
IUUC-Ggo-044856	Gorilla gorilla	79.22	0.00e+00	2202.00
IUUC-Hsa-045888	Homo sapiens	98.97	0.00e+00	2984.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	1.00e-15	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	95.13	0.00e+00	2840.00
IUUC-Lch-050483	Latimeria chalumnae	65.28	0.00e+00	2030.00
IUUC-Lpe-051537	Leersia perrieri	31.69	2.00e-91	331.00
IUUC-Loc-052550	Lepisosteus oculatus	69.60	0.00e+00	2106.00
IUUC-Laf-053761	Loxodonta africana	92.59	0.00e+00	2714.00
IUUC-Mpo-057317	Magnaporthe poae	28.65	1.00e-104	375.00
IUUC-Mga-059358	Meleagris gallopavo	80.72	0.00e+00	2411.00
IUUC-Mmr-060863	Microcebus murinus	95.38	0.00e+00	2867.00
IUUC-Mdo-061957	Monodelphis domestica	87.68	0.00e+00	2694.00
IUUC-Mmu-063944	Mus musculus	91.94	0.00e+00	2757.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	55.80
IUUC-Mpu-066719	Mustela putorius furo	93.01	0.00e+00	2835.00
IUUC-Mlu-067366	Myotis lucifugus	84.39	0.00e+00	2547.00
IUUC-Nle-069256	Nomascus leucogenys	98.13	0.00e+00	2942.00
IUUC-Ont-071756	Oreochromis niloticus	61.31	0.00e+00	1887.00
IUUC-Oan-073568	Ornithorhynchus anatinus	88.01	0.00e+00	2688.00
IUUC-Ocu-073961	Oryctolagus cuniculus	91.14	0.00e+00	2759.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	1.00e-16	82.00
IUUC-Olo-080668	Oryza longistaminata	38.83	4.00e-16	81.60
IUUC-Opu-083164	Oryza punctata	31.86	2.00e-87	318.00
IUUC-Osa-085487	Oryza sativa	38.83	1.00e-16	82.00
IUUC-Ola-086448	Oryzias latipes	62.28	0.00e+00	1868.00
IUUC-Oga-088501	Otolemur garnettii	90.77	0.00e+00	2394.00
IUUC-Oar-090162	Ovis aries	88.95	0.00e+00	2635.00
IUUC-Ptr-090816	Pan troglodytes	99.10	0.00e+00	2991.00
IUUC-Pan-092764	Papio anubis	97.55	0.00e+00	2918.00
IUUC-Psi-093918	Pelodiscus sinensis	80.82	0.00e+00	2220.00
IUUC-Pfo-096672	Poecilia formosa	61.03	0.00e+00	1815.00
IUUC-Pab-097854	Pongo abelii	92.94	0.00e+00	2215.00
IUUC-Pca-100241	Procavia capensis	91.85	0.00e+00	1811.00
IUUC-Pva-103035	Pteropus vampyrus	83.38	0.00e+00	2201.00
IUUC-Rno-105574	Rattus norvegicus	90.64	0.00e+00	2694.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.35	3.00e-73	270.00
IUUC-Sar-113477	Sorex araneus	88.63	0.00e+00	2412.00
IUUC-Ssc-116132	Sus scrofa	92.66	0.00e+00	2428.00
IUUC-Tgu-117452	Taeniopygia guttata	81.64	0.00e+00	2398.00
IUUC-Tru-117561	Takifugu rubripes	63.96	0.00e+00	1747.00
IUUC-Tsy-119271	Tarsius syrichta	95.61	0.00e+00	2196.00
IUUC-Tni-119650	Tetraodon nigroviridis	60.10	0.00e+00	1820.00
IUUC-Tur-126632	Triticum urartu	32.35	8.00e-101	362.00
IUUC-Tbe-127890	Tupaia belangeri	91.36	0.00e+00	1568.00
IUUC-Ttr-128546	Tursiops truncatus	88.10	0.00e+00	2006.00
IUUC-Vpa-130432	Vicugna pacos	89.97	0.00e+00	1584.00
IUUC-Xtr-132008	Xenopus tropicalis	69.94	0.00e+00	2127.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence