iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074425

Ensembl Protein ID

ENSOCUP00000012907.2

UniProt Accession

G1T8K2; G1T8K2_RABIT

Protein Name

Uncharacterized protein

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015018.2	ENSOCUT00000015019.2	ENSOCUP00000012907.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.60e-16	60.0	427	483

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 427  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDSGQVGLYPANYVEAIQ 483
           799************************.9**********.59*************9885 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSVAYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGYRLCSD LMNCLHERAR IEKAYAQQLT 60
EWARRWRQLV EKGPQYGTVE KAWIALMSEA ERVSELHLEV KAALMNEDFE KIKNWQKDAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGTCG CTTACGACGA TTCCGTCGGA GTGGAAGTGT CCAGCGATAG CTTCTGGGAG 60
GTAACACCCC GCCGGCTCCC GAGAGCGCCG CGCCTGGCCG TAGCCTGGCC ACCCTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

KEGG

ocu:100339444

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	93.62	0.00e+00	853.00
IUUC-Apl-003574	Anas platyrhynchos	85.83	0.00e+00	764.00
IUUC-Aca-004251	Anolis carolinensis	82.40	0.00e+00	748.00
IUUC-Ame-011756	Astyanax mexicanus	66.47	0.00e+00	664.00
IUUC-Bta-013193	Bos taurus	91.36	0.00e+00	807.00
IUUC-Cel-018168	Caenorhabditis elegans	31.64	8.00e-60	224.00
IUUC-Cja-018756	Callithrix jacchus	93.62	0.00e+00	837.00
IUUC-Cfa-020545	Canis familiaris	94.44	0.00e+00	887.00
IUUC-Cpo-022000	Cavia porcellus	90.12	0.00e+00	894.00
IUUC-Csa-024030	Chlorocebus sabaeus	91.91	0.00e+00	747.00
IUUC-Cin-025707	Ciona intestinalis	43.65	4.00e-107	381.00
IUUC-Csv-026244	Ciona savignyi	44.70	2.00e-56	211.00
IUUC-Dre-028104	Danio rerio	62.05	4.00e-161	561.00
IUUC-Dno-029429	Dasypus novemcinctus	90.53	0.00e+00	779.00
IUUC-Dor-030122	Dipodomys ordii	86.42	0.00e+00	772.00
IUUC-Dme-032120	Drosophila melanogaster	43.57	3.00e-103	368.00
IUUC-Eca-033367	Equus caballus	91.93	0.00e+00	833.00
IUUC-Eeu-034821	Erinaceus europaeus	76.13	0.00e+00	656.00
IUUC-Fca-036079	Felis catus	93.80	0.00e+00	850.00
IUUC-Fal-036682	Ficedula albicollis	85.96	0.00e+00	763.00
IUUC-Gmo-039681	Gadus morhua	65.64	7.00e-155	540.00
IUUC-Gga-040717	Gallus gallus	85.96	0.00e+00	766.00
IUUC-Gac-042262	Gasterosteus aculeatus	65.57	3.00e-171	594.00
IUUC-Ggo-044841	Gorilla gorilla	93.42	0.00e+00	809.00
IUUC-Hsa-046411	Homo sapiens	93.21	0.00e+00	807.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	94.24	0.00e+00	832.00
IUUC-Loc-051975	Lepisosteus oculatus	71.10	0.00e+00	680.00
IUUC-Laf-053839	Loxodonta africana	88.73	0.00e+00	809.00
IUUC-Mcc-055783	Macaca mulatta	92.59	0.00e+00	803.00
IUUC-Mga-060087	Meleagris gallopavo	80.00	0.00e+00	694.00
IUUC-Mvi-060548	Microbotryum violaceum	40.74	5.00e-07	50.80
IUUC-Mmr-060827	Microcebus murinus	94.24	0.00e+00	862.00
IUUC-Mmu-064109	Mus musculus	93.83	0.00e+00	857.00
IUUC-Mpu-066591	Mustela putorius furo	94.03	0.00e+00	859.00
IUUC-Mlu-067826	Myotis lucifugus	92.80	0.00e+00	846.00
IUUC-Nle-069797	Nomascus leucogenys	93.00	0.00e+00	805.00
IUUC-Oan-073076	Ornithorhynchus anatinus	85.71	2.00e-154	538.00
IUUC-Ola-087556	Oryzias latipes	66.01	2.00e-161	561.00
IUUC-Oga-089009	Otolemur garnettii	86.97	0.00e+00	795.00
IUUC-Oar-089806	Ovis aries	91.36	0.00e+00	807.00
IUUC-Ptr-091111	Pan troglodytes	93.00	0.00e+00	804.00
IUUC-Pan-091749	Papio anubis	89.86	0.00e+00	790.00
IUUC-Psi-093704	Pelodiscus sinensis	88.03	0.00e+00	791.00
IUUC-Pfo-096680	Poecilia formosa	64.60	5.00e-167	580.00
IUUC-Pab-098584	Pongo abelii	92.43	3.00e-158	551.00
IUUC-Pva-102649	Pteropus vampyrus	92.80	0.00e+00	829.00
IUUC-Rno-105431	Rattus norvegicus	93.24	0.00e+00	870.00
IUUC-Sha-106641	Sarcophilus harrisii	89.48	0.00e+00	798.00
IUUC-Sar-113461	Sorex araneus	81.28	0.00e+00	714.00
IUUC-Ssc-115349	Sus scrofa	92.78	0.00e+00	815.00
IUUC-Tgu-116876	Taeniopygia guttata	85.96	0.00e+00	764.00
IUUC-Tru-118306	Takifugu rubripes	68.41	9.00e-174	602.00
IUUC-Tsy-118901	Tarsius syrichta	84.18	2.00e-149	522.00
IUUC-Tni-120120	Tetraodon nigroviridis	69.06	7.00e-178	616.00
IUUC-Xtr-132925	Xenopus tropicalis	81.72	0.00e+00	738.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence