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Tag Content
iUUCD ID IUUC-Aml-001194
Ensembl Protein ID ENSAMEP00000015794.1
UniProt Accession G1M8X4; G1M8X4_AILME
Genbank Protein ID ENSAMEP00000015794
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01177962
Gene Name HCLS1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000014955.1 ENSAMET00000016449.1 ENSAMEP00000015794.1
ENSAMEG00000014955.1 ENSAMET00000016457.1 ENSAMEP00000015802.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.20e-11 43.6 430 481
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
    ++lydy+++ +de ++ d+++ i e degW++g +g GlfP+n+v+ l
   Q: 430 IALYDYQGEGSDEISFDPDDIITDI--EMVDEGWWRG--RCHGHFGLFPANYVKLL 481
    79**********************9..9*********..8*************977 PP
   

Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MWKSVVGHDV SVTVETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGRTE HINIHQLRNK 60
VSEEHDSLKK KEMESGPKAS HGYGGRFGVE RDRMDKSAVG HEYVAEVEKH SSQTDAAKGF 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Aml-001194|UBD,SH3|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTGGAAGT CTGTAGTAGG GCATGATGTA TCTGTTACCG TGGAGACCCA GGGTGATGAC 60
TGGGACACAG ACCCTGACTT TGTGGTGAGT TTGGGAGTAG CTTTGCTTGG AAAATCAATA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Aml-001194|UBD,SH3|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Bta-012591 Bos taurus 86.53 0.00e+00 691.00
IUUC-Cja-019982 Callithrix jacchus 84.16 0.00e+00 686.00
IUUC-Cfa-020262 Canis familiaris 88.46 0.00e+00 706.00
IUUC-Cpo-021362 Cavia porcellus 81.33 0.00e+00 640.00
IUUC-Csa-023911 Chlorocebus sabaeus 85.09 0.00e+00 691.00
IUUC-Dor-030437 Dipodomys ordii 75.31 6.00e-172 597.00
IUUC-Ete-033160 Echinops telfairi 72.71 5.00e-153 533.00
IUUC-Eca-033269 Equus caballus 85.89 0.00e+00 740.00
IUUC-Eeu-035032 Erinaceus europaeus 71.69 4.00e-127 447.00
IUUC-Fca-035999 Felis catus 87.90 0.00e+00 800.00
IUUC-Gga-040335 Gallus gallus 67.14 7.00e-105 374.00
IUUC-Ggo-044505 Gorilla gorilla 83.95 0.00e+00 686.00
IUUC-Hsa-046728 Homo sapiens 89.55 6.00e-169 587.00
IUUC-Itr-048592 Ictidomys tridecemlineatus 67.21 4.00e-165 574.00
IUUC-Laf-054202 Loxodonta africana 80.93 0.00e+00 663.00
IUUC-Mcc-055824 Macaca mulatta 84.89 0.00e+00 694.00
IUUC-Mmr-061281 Microcebus murinus 73.25 2.00e-167 581.00
IUUC-Mdo-062515 Monodelphis domestica 67.48 2.00e-149 522.00
IUUC-Mmu-064341 Mus musculus 80.61 0.00e+00 674.00
IUUC-Mpu-066565 Mustela putorius furo 91.29 0.00e+00 754.00
IUUC-Mlu-066942 Myotis lucifugus 81.58 0.00e+00 684.00
IUUC-Nle-069436 Nomascus leucogenys 85.27 0.00e+00 691.00
IUUC-Opr-070288 Ochotona princeps 76.45 7.00e-169 586.00
IUUC-Ocu-074686 Oryctolagus cuniculus 79.88 3.00e-178 618.00
IUUC-Ola-086894 Oryzias latipes 59.79 7.00e-94 337.00
IUUC-Oga-088585 Otolemur garnettii 77.28 0.00e+00 664.00
IUUC-Oar-089686 Ovis aries 87.04 0.00e+00 742.00
IUUC-Ptr-090461 Pan troglodytes 90.40 1.00e-170 592.00
IUUC-Pan-091887 Papio anubis 84.65 0.00e+00 693.00
IUUC-Psi-093785 Pelodiscus sinensis 51.65 3.00e-139 488.00
IUUC-Pab-098222 Pongo abelii 85.30 0.00e+00 692.00
IUUC-Pca-100668 Procavia capensis 82.85 0.00e+00 682.00
IUUC-Pva-102767 Pteropus vampyrus 73.66 3.00e-170 591.00
IUUC-Rno-106001 Rattus norvegicus 82.89 0.00e+00 679.00
IUUC-Sar-113338 Sorex araneus 76.41 6.00e-175 606.00
IUUC-Ssc-116027 Sus scrofa 84.34 0.00e+00 733.00
IUUC-Tgu-117472 Taeniopygia guttata 56.51 3.00e-147 514.00
Created Date 25-Jun-2017

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