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Tag Content
iUUCD ID IUUC-Itr-048592
Ensembl Protein ID ENSSTOP00000008987.2
UniProt Accession I3MEN7; I3MEN7_ICTTR
Genbank Protein ID ENSSTOP00000008987
Protein Name Uncharacterized protein
Genbank Nucleotide ID AGTP01049938
Gene Name HCLS1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSTOG00000010016.2 ENSSTOT00000010018.2 ENSSTOP00000008987.2
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 7.60e-13 48.2 443 494
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
    +lydy+++ +deL++ d+++ i e+ degW++g +g GlfP+n+v+ l
   Q: 443 VALYDYQGEGSDELSFDPDDIITDI--EKVDEGWWRG--RCHGHFGLFPANYVKLL 494
    68***********************..9*********..8*************977 PP
   

Organism Ictidomys tridecemlineatus
Protein Sequence
(Fasta)
MWKSVVGHDV SVSVETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGRKE HINIHQLRSK 60
VSEEHDVLKK KEMESGPKAS HGYGGRFGVE RDRMDKSAVG HEYVAEVEKH SSQTDAAKGF 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Itr-048592|UBD,SH3|Ictidomys tridecemlineatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGATGTGGAA GTCTGTAGTG GGTCATGATG TATCTGTTTC CGTGGAGACC CAGGGTGATG 60
ACTGGGACAC AGACCCTGAC TTTGTGGTGA GTTTGAAAGT CGTTTTTCTT GAACGATGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Itr-048592|UBD,SH3|Ictidomys tridecemlineatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001194 Ailuropoda melanoleuca 67.75 9.00e-172 596.00
IUUC-Bta-012591 Bos taurus 74.08 8.00e-141 493.00
IUUC-Cja-019982 Callithrix jacchus 67.40 3.00e-161 560.00
IUUC-Cfa-020262 Canis familiaris 65.18 5.00e-157 547.00
IUUC-Cpo-021362 Cavia porcellus 66.24 4.00e-155 540.00
IUUC-Csa-023911 Chlorocebus sabaeus 74.63 3.00e-140 491.00
IUUC-Dor-030437 Dipodomys ordii 60.25 5.00e-139 487.00
IUUC-Ete-033160 Echinops telfairi 60.10 2.00e-81 295.00
IUUC-Eca-033269 Equus caballus 66.31 2.00e-164 571.00
IUUC-Eeu-035032 Erinaceus europaeus 61.11 4.00e-85 308.00
IUUC-Fca-035999 Felis catus 63.46 5.00e-159 553.00
IUUC-Fal-037107 Ficedula albicollis 60.86 3.00e-104 372.00
IUUC-Gga-040335 Gallus gallus 62.27 2.00e-104 372.00
IUUC-Ggo-044505 Gorilla gorilla 67.68 2.00e-165 575.00
IUUC-Hsa-046728 Homo sapiens 73.59 5.00e-138 484.00
IUUC-Laf-054202 Loxodonta africana 72.62 1.00e-134 473.00
IUUC-Mcc-055824 Macaca mulatta 74.38 3.00e-140 491.00
IUUC-Mmr-061281 Microcebus murinus 56.56 3.00e-95 341.00
IUUC-Mdo-062515 Monodelphis domestica 56.23 4.00e-126 444.00
IUUC-Mmu-064341 Mus musculus 73.96 4.00e-140 490.00
IUUC-Mpu-066565 Mustela putorius furo 72.75 1.00e-135 476.00
IUUC-Mlu-066942 Myotis lucifugus 62.89 8.00e-155 540.00
IUUC-Nle-069436 Nomascus leucogenys 74.57 1.00e-140 492.00
IUUC-Opr-070288 Ochotona princeps 62.84 1.00e-134 473.00
IUUC-Ocu-074686 Oryctolagus cuniculus 74.15 1.00e-126 446.00
IUUC-Ola-086894 Oryzias latipes 47.62 4.00e-83 301.00
IUUC-Oga-088585 Otolemur garnettii 60.75 5.00e-149 520.00
IUUC-Oar-089686 Ovis aries 67.62 8.00e-170 589.00
IUUC-Ptr-090461 Pan troglodytes 74.33 9.00e-140 489.00
IUUC-Pan-091887 Papio anubis 74.88 2.00e-141 495.00
IUUC-Pab-098222 Pongo abelii 73.84 1.00e-140 492.00
IUUC-Pca-100668 Procavia capensis 65.52 7.00e-159 553.00
IUUC-Pva-102767 Pteropus vampyrus 62.36 3.00e-95 341.00
IUUC-Rno-106001 Rattus norvegicus 64.97 8.00e-159 553.00
IUUC-Sar-113338 Sorex araneus 63.25 1.00e-102 366.00
IUUC-Ssc-116027 Sus scrofa 67.38 2.00e-167 582.00
Created Date 25-Jun-2017

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