iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001899

Ensembl Protein ID

ENSAMEP00000018482.1

UniProt Accession

G1MGJ8; G1MGJ8_AILME

Genbank Protein ID

ENSAMEP00000018482

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01131479

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000017471.1	ENSAMET00000019225.1	ENSAMEP00000018482.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.30e-31	104.7	531	563
UBD/Beta-Prp	8.50e-46	156.5	527	741

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+   +  +l+s+s Dgt+++W+++
   Q: 531  GHTDAVWGLAYsaaH-QRLLSCSADGTLRLWNTT 563
           8**********9853.89**************76 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk......ghedsvlslsfspsgdklvsGshdrtirvwdletgqc 128
             l gh+++v+ + +s   + l+++s D+t+++w+     +  ++       g  +sv ++s++p  +++v+  +  +  ++++et+q 
   Q: 527  GPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFndnqelGIPASVDLVSSDP--SHMVASFSKGYTSIFNMETQQR 613
           5689******************************8887766666661444444444555566666..8888888899************ PP
   S: 129  lee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           + +      t  + +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l++
   Q: 614  ILTlesnldTIGNSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLES 701
           **9999866555566668888899*99**************************98.********************************* PP
   S: 212  gecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 702  KTCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 741
           ***********999999******************97655 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

XXXXGAARAQ YSLPGILHFL QHEWARFEVE RAQWEVERAE LQAQIAFLQG ERKGQEILKK 60
DLVRRIKMLE YALKQERAKY HKLKYGTELN QGDMKPPSYD SDEGNETEVQ PQQNSQLMWK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NGGGGGCGGC GCGAGCCCAA TACAGCCTCC CTGGGATCCT GCACTTCCTG 60
CAGCATGAGT GGGCCCGCTT CGAGGTTGAG AGAGCCCAGT GGGAGGTGGA GCGGGCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003927	Anas platyrhynchos	87.66	0.00e+00	1120.00
IUUC-Aca-004933	Anolis carolinensis	80.81	0.00e+00	1159.00
IUUC-Ame-010997	Astyanax mexicanus	75.53	0.00e+00	1054.00
IUUC-Bta-013077	Bos taurus	97.82	0.00e+00	1359.00
IUUC-Cja-018973	Callithrix jacchus	98.23	0.00e+00	1368.00
IUUC-Cfa-020988	Canis familiaris	94.74	0.00e+00	1253.00
IUUC-Cpo-022496	Cavia porcellus	96.73	0.00e+00	1359.00
IUUC-Csa-023829	Chlorocebus sabaeus	97.96	0.00e+00	1363.00
IUUC-Dre-028560	Danio rerio	70.24	0.00e+00	954.00
IUUC-Dno-029742	Dasypus novemcinctus	91.29	0.00e+00	1291.00
IUUC-Dor-030721	Dipodomys ordii	88.30	0.00e+00	1220.00
IUUC-Eca-033760	Equus caballus	98.15	0.00e+00	1293.00
IUUC-Eeu-034953	Erinaceus europaeus	96.88	0.00e+00	753.00
IUUC-Fca-036530	Felis catus	98.01	0.00e+00	1313.00
IUUC-Fal-037353	Ficedula albicollis	81.65	0.00e+00	895.00
IUUC-Gga-040132	Gallus gallus	87.53	0.00e+00	1141.00
IUUC-Gac-041713	Gasterosteus aculeatus	75.33	0.00e+00	1046.00
IUUC-Ggo-045455	Gorilla gorilla	87.55	0.00e+00	1165.00
IUUC-Hsa-046415	Homo sapiens	97.82	0.00e+00	1363.00
IUUC-Lch-050475	Latimeria chalumnae	84.30	0.00e+00	1195.00
IUUC-Loc-051859	Lepisosteus oculatus	79.97	0.00e+00	1141.00
IUUC-Laf-053537	Loxodonta africana	97.01	0.00e+00	1389.00
IUUC-Mcc-055817	Macaca mulatta	97.96	0.00e+00	1363.00
IUUC-Meu-055946	Macropus eugenii	69.48	0.00e+00	867.00
IUUC-Mga-059694	Meleagris gallopavo	87.78	0.00e+00	1115.00
IUUC-Mmr-060768	Microcebus murinus	98.23	0.00e+00	1363.00
IUUC-Mdo-061901	Monodelphis domestica	88.74	0.00e+00	1281.00
IUUC-Mmu-064154	Mus musculus	96.05	0.00e+00	1343.00
IUUC-Mpu-065827	Mustela putorius furo	93.46	0.00e+00	1380.00
IUUC-Mlu-067102	Myotis lucifugus	97.14	0.00e+00	1352.00
IUUC-Ncr-068831	Neurospora crassa	39.60	5.00e-22	99.80
IUUC-Nle-070008	Nomascus leucogenys	97.87	0.00e+00	1295.00
IUUC-Opr-071067	Ochotona princeps	61.31	3.00e-179	621.00
IUUC-Ont-072025	Oreochromis niloticus	75.03	0.00e+00	1046.00
IUUC-Oan-072950	Ornithorhynchus anatinus	91.32	0.00e+00	1165.00
IUUC-Ocu-074316	Oryctolagus cuniculus	96.73	0.00e+00	1269.00
IUUC-Ola-087279	Oryzias latipes	72.82	0.00e+00	1016.00
IUUC-Oga-088284	Otolemur garnettii	97.96	0.00e+00	1382.00
IUUC-Oar-090304	Ovis aries	98.23	0.00e+00	1367.00
IUUC-Ptr-091052	Pan troglodytes	97.96	0.00e+00	1365.00
IUUC-Pan-092270	Papio anubis	93.91	0.00e+00	1327.00
IUUC-Psi-093907	Pelodiscus sinensis	87.74	0.00e+00	1046.00
IUUC-Pfo-097042	Poecilia formosa	74.00	0.00e+00	1123.00
IUUC-Pab-098110	Pongo abelii	97.96	0.00e+00	1365.00
IUUC-Pca-100266	Procavia capensis	84.02	0.00e+00	958.00
IUUC-Pva-102824	Pteropus vampyrus	95.51	0.00e+00	1310.00
IUUC-Pgr-103483	Puccinia graminis	37.28	8.00e-57	216.00
IUUC-Rno-105638	Rattus norvegicus	96.05	0.00e+00	1348.00
IUUC-Sha-107004	Sarcophilus harrisii	88.40	0.00e+00	1125.00
IUUC-Sre-115115	Sporisorium reilianum	34.11	2.00e-64	241.00
IUUC-Ssc-115280	Sus scrofa	98.10	0.00e+00	1364.00
IUUC-Tgu-116759	Taeniopygia guttata	87.93	0.00e+00	1140.00
IUUC-Tru-117944	Takifugu rubripes	74.50	0.00e+00	1033.00
IUUC-Tsy-119405	Tarsius syrichta	86.04	0.00e+00	1077.00
IUUC-Tni-120571	Tetraodon nigroviridis	74.03	0.00e+00	1043.00
IUUC-Tme-126990	Tuber melanosporum	26.15	6.00e-36	145.00
IUUC-Uma-129659	Ustilago maydis	34.96	7.00e-65	242.00
IUUC-Vpa-130294	Vicugna pacos	97.29	0.00e+00	1277.00
IUUC-Xma-134233	Xiphophorus maculatus	67.56	0.00e+00	901.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence