iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	3.10e-13	49.4	19	47

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpRgc 30
           e+ W+Cs+CTf+N++ea+kC mC+ ++g+
   Q: 19   EGYWDCSVCTFRNSAEAFKCMMCDVRKGT 47
           677************************95 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MGDKKSPTRP KRPNPASDEG YWDCSVCTFR NSAEAFKCMM CDVRKGTSTR KPRPVSQLVA 60
QQVTQQFVPP TQSKKEKKDK VEKDKSEKEA ASKKNCHKRT RPRLKNVDRS SAQHLEVTVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCGGCGG CGGCGGCTGC AGCTCGCGGC GCGGCCTTCC CCGCCCCCTC GCCTCCGCGC 60
TTCCGCCGGC CCCTCGCCTC GGCGCTGACA GACGGGCCGC GGCCTCGCGC GCGTCGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR033774--YAF2_RYBP
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF17219--YAF2_RYBP
PF00641--zf-RanBP

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0003713--F:transcription coactivator activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001905	Ailuropoda melanoleuca	91.46	1.00e-41	161.00
IUUC-Aca-004478	Anolis carolinensis	91.11	7.00e-55	206.00
IUUC-Ame-011908	Astyanax mexicanus	78.57	1.00e-60	225.00
IUUC-Bta-012681	Bos taurus	86.67	2.00e-39	154.00
IUUC-Cja-018878	Callithrix jacchus	80.39	8.00e-45	172.00
IUUC-Cfa-020696	Canis familiaris	79.59	6.00e-40	156.00
IUUC-Cpo-022486	Cavia porcellus	91.28	1.00e-43	169.00
IUUC-Cho-024392	Choloepus hoffmanni	91.93	2.00e-40	157.00
IUUC-Cin-025723	Ciona intestinalis	47.76	6.00e-21	93.20
IUUC-Dre-028175	Danio rerio	75.57	2.00e-42	164.00
IUUC-Dno-030093	Dasypus novemcinctus	87.50	5.00e-20	89.70
IUUC-Dme-031799	Drosophila melanogaster	51.88	2.00e-28	118.00
IUUC-Ete-032826	Echinops telfairi	62.80	7.00e-32	129.00
IUUC-Eeu-034971	Erinaceus europaeus	91.82	6.00e-39	153.00
IUUC-Fca-036586	Felis catus	90.00	2.00e-19	87.40
IUUC-Gmo-038950	Gadus morhua	69.59	2.00e-47	181.00
IUUC-Gga-040428	Gallus gallus	90.56	7.00e-44	169.00
IUUC-Gac-042503	Gasterosteus aculeatus	74.39	3.00e-50	191.00
IUUC-Ggo-044644	Gorilla gorilla	90.70	7.00e-44	169.00
IUUC-Hsa-046310	Homo sapiens	80.39	8.00e-45	172.00
IUUC-Itr-048494	Ictidomys tridecemlineatus	94.12	2.00e-24	102.00
IUUC-Lch-050130	Latimeria chalumnae	86.11	2.00e-60	224.00
IUUC-Loc-052825	Lepisosteus oculatus	70.83	2.00e-49	188.00
IUUC-Laf-054318	Loxodonta africana	90.56	1.00e-46	178.00
IUUC-Mcc-054885	Macaca mulatta	94.12	2.00e-24	104.00
IUUC-Meu-056465	Macropus eugenii	68.36	4.00e-48	183.00
IUUC-Mga-059338	Meleagris gallopavo	89.87	5.00e-17	79.70
IUUC-Mmr-060766	Microcebus murinus	81.97	9.00e-26	108.00
IUUC-Mdo-062390	Monodelphis domestica	89.44	2.00e-47	181.00
IUUC-Mmu-063437	Mus musculus	90.56	2.00e-57	214.00
IUUC-Nle-070014	Nomascus leucogenys	80.39	8.00e-45	172.00
IUUC-Ont-071471	Oreochromis niloticus	76.92	1.00e-58	218.00
IUUC-Ocu-073946	Oryctolagus cuniculus	86.55	1.00e-57	215.00
IUUC-Ola-086923	Oryzias latipes	77.35	4.00e-60	223.00
IUUC-Oga-089162	Otolemur garnettii	72.83	1.00e-25	108.00
IUUC-Oar-090289	Ovis aries	79.25	7.00e-21	92.00
IUUC-Ptr-091285	Pan troglodytes	80.39	8.00e-45	172.00
IUUC-Pma-094646	Petromyzon marinus	66.18	7.00e-43	166.00
IUUC-Pfo-097428	Poecilia formosa	69.88	1.00e-42	165.00
IUUC-Pva-102993	Pteropus vampyrus	91.11	1.00e-48	185.00
IUUC-Sha-107285	Sarcophilus harrisii	88.89	1.00e-47	182.00
IUUC-Tgu-116993	Taeniopygia guttata	90.00	2.00e-43	168.00
IUUC-Tru-118599	Takifugu rubripes	74.81	3.00e-49	187.00
IUUC-Tsy-119409	Tarsius syrichta	89.92	9.00e-19	85.50
IUUC-Tni-120574	Tetraodon nigroviridis	73.48	9.00e-56	209.00
IUUC-Ttr-128187	Tursiops truncatus	90.85	8.00e-41	159.00
IUUC-Vpa-130247	Vicugna pacos	89.47	3.00e-42	164.00
IUUC-Xtr-132148	Xenopus tropicalis	85.00	9.00e-65	239.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence