iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088523

Ensembl Protein ID

ENSOGAP00000013843.2

UniProt Accession

H0XDA8; H0XDA8_OTOGA

Genbank Protein ID

ENSOGAP00000013843

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03005606

Gene Name

TRIM71

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000015458.2	ENSOGAT00000015462.2	ENSOGAP00000013843.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.40e-06	28.0	12	95

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..................................kdgplvlpCgHvfhadCl..qkw...pglknssskefrCPlCr 46
           C++C+e++                                  ++ ++vlpC H+f++ Cl  +++    g    +  + rCP+C+
   Q: 12   CLLCKEMCgspaplssnssasssssqtstssggggggpgaaaRR-LHVLPCLHAFCRPCLeaHRLpaaGGGAPGEPLKLRCPVCD 95
           99998888888888888777777777777777777777777444.***************5555599977777899999*****5 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MASFPETDFQ ICLLCKEMCG SPAPLSSNSS ASSSSSQTST SSGGGGGGPG AAARRLHVLP 60
CLHAFCRPCL EAHRLPAAGG GAPGEPLKLR CPVCDQKVVL AEAAGMDALP SSAFLLSNLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCGT TCCCCGAGAC CGACTTCCAG ATCTGCCTGC TGTGCAAGGA GATGTGCGGC 60
TCACCGGCGC CGCTTTCCTC CAACTCTTCA GCGTCGTCCT CTTCCTCGCA GACGTCCACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR017868--Filamin/ABP280_repeat-like
IPR001298--Filamin/ABP280_rpt
IPR013783--Ig-like_fold
IPR014756--Ig_E-set
IPR001258--NHL_repeat
IPR013017--NHL_repeat_subgr
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50194--FILAMIN_REPEAT
PS51125--NHL
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00630--Filamin
PF01436--NHL
PF00643--zf-B_box

SMART

SM00557--IG_FLMN
SM00184--RING

Gene Ontology

GO:0000932--C:P-body
GO:0035198--F:miRNA binding
GO:0030371--F:translation repressor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0008543--P:fibroblast growth factor receptor signaling pathway
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035278--P:miRNA mediated inhibition of translation
GO:0010586--P:miRNA metabolic process
GO:0001843--P:neural tube closure
GO:2000637--P:positive regulation of gene silencing by miRNA
GO:0051865--P:protein autoubiquitination
GO:2000177--P:regulation of neural precursor cell proliferation
GO:0072089--P:stem cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001234	Ailuropoda melanoleuca	97.78	0.00e+00	1182.00
IUUC-Apl-003905	Anas platyrhynchos	93.66	0.00e+00	1152.00
IUUC-Aca-004326	Anolis carolinensis	89.53	0.00e+00	1125.00
IUUC-Ani-009171	Aspergillus nidulans	27.27	3.90e-02	32.70
IUUC-Ame-011573	Astyanax mexicanus	66.90	0.00e+00	1106.00
IUUC-Bta-013395	Bos taurus	96.82	0.00e+00	1190.00
IUUC-Cel-018188	Caenorhabditis elegans	36.14	1.00e-108	388.00
IUUC-Cja-019863	Callithrix jacchus	96.68	0.00e+00	1197.00
IUUC-Cfa-020285	Canis familiaris	95.68	0.00e+00	1186.00
IUUC-Cpo-021879	Cavia porcellus	83.77	0.00e+00	1350.00
IUUC-Csa-024271	Chlorocebus sabaeus	96.51	0.00e+00	1195.00
IUUC-Cho-024376	Choloepus hoffmanni	97.60	0.00e+00	1179.00
IUUC-Cin-025406	Ciona intestinalis	51.09	1.00e-171	596.00
IUUC-Cne-027010	Cryptococcus neoformans	26.00	1.80e-02	31.60
IUUC-Dre-027699	Danio rerio	68.09	0.00e+00	1117.00
IUUC-Dno-029022	Dasypus novemcinctus	95.82	0.00e+00	1181.00
IUUC-Dor-031072	Dipodomys ordii	95.02	0.00e+00	1181.00
IUUC-Dme-031997	Drosophila melanogaster	47.08	4.00e-70	259.00
IUUC-Ete-032228	Echinops telfairi	97.76	0.00e+00	819.00
IUUC-Eca-033373	Equus caballus	98.83	0.00e+00	1056.00
IUUC-Eeu-034463	Erinaceus europaeus	96.11	0.00e+00	1135.00
IUUC-Fca-036184	Felis catus	95.99	0.00e+00	1188.00
IUUC-Fal-036918	Ficedula albicollis	85.78	0.00e+00	1157.00
IUUC-Fox-038003	Fusarium oxysporum	31.67	2.00e-03	36.20
IUUC-Gmo-039415	Gadus morhua	71.02	0.00e+00	857.00
IUUC-Gga-040379	Gallus gallus	91.71	0.00e+00	1153.00
IUUC-Gac-042330	Gasterosteus aculeatus	67.85	0.00e+00	899.00
IUUC-Gma-043819	Glycine max	23.05	2.00e-12	68.60
IUUC-Ggo-045208	Gorilla gorilla	96.51	0.00e+00	1191.00
IUUC-Hsa-045988	Homo sapiens	96.68	0.00e+00	1196.00
IUUC-Itr-048371	Ictidomys tridecemlineatus	98.29	0.00e+00	1194.00
IUUC-Lch-050324	Latimeria chalumnae	79.53	0.00e+00	1100.00
IUUC-Loc-052322	Lepisosteus oculatus	69.59	0.00e+00	1177.00
IUUC-Laf-054272	Loxodonta africana	96.43	0.00e+00	1173.00
IUUC-Mcc-055125	Macaca mulatta	96.51	0.00e+00	1194.00
IUUC-Meu-055934	Macropus eugenii	94.13	0.00e+00	1041.00
IUUC-Mga-059930	Meleagris gallopavo	93.50	0.00e+00	1147.00
IUUC-Mmr-060662	Microcebus murinus	96.18	0.00e+00	1191.00
IUUC-Mdo-062918	Monodelphis domestica	91.31	0.00e+00	1160.00
IUUC-Mmu-064351	Mus musculus	85.14	0.00e+00	1153.00
IUUC-Mpu-066325	Mustela putorius furo	98.25	0.00e+00	1051.00
IUUC-Mlu-067171	Myotis lucifugus	95.23	0.00e+00	1183.00
IUUC-Nle-069692	Nomascus leucogenys	96.51	0.00e+00	1195.00
IUUC-Opr-070354	Ochotona princeps	95.03	0.00e+00	1159.00
IUUC-Ont-072125	Oreochromis niloticus	64.87	0.00e+00	1075.00
IUUC-Oan-073079	Ornithorhynchus anatinus	94.87	0.00e+00	1159.00
IUUC-Ocu-073910	Oryctolagus cuniculus	95.51	0.00e+00	1184.00
IUUC-Ola-087162	Oryzias latipes	64.85	0.00e+00	1066.00
IUUC-Oar-090009	Ovis aries	97.10	0.00e+00	689.00
IUUC-Ptr-091173	Pan troglodytes	96.68	0.00e+00	1197.00
IUUC-Pan-091750	Papio anubis	96.35	0.00e+00	1191.00
IUUC-Psi-093053	Pelodiscus sinensis	89.23	0.00e+00	1086.00
IUUC-Pma-094227	Petromyzon marinus	58.63	2.00e-174	605.00
IUUC-Pfo-096980	Poecilia formosa	62.81	0.00e+00	1033.00
IUUC-Pab-098189	Pongo abelii	96.51	0.00e+00	1193.00
IUUC-Pva-103126	Pteropus vampyrus	96.31	0.00e+00	1184.00
IUUC-Rno-105653	Rattus norvegicus	86.48	0.00e+00	1165.00
IUUC-Sce-106389	Saccharomyces cerevisiae	25.64	5.00e-02	32.00
IUUC-Sha-107178	Sarcophilus harrisii	94.34	0.00e+00	1156.00
IUUC-Sar-113613	Sorex araneus	84.98	0.00e+00	977.00
IUUC-Tgu-116963	Taeniopygia guttata	93.16	0.00e+00	1146.00
IUUC-Tru-117942	Takifugu rubripes	65.93	0.00e+00	1087.00
IUUC-Tsy-119075	Tarsius syrichta	89.73	0.00e+00	1061.00
IUUC-Tni-120704	Tetraodon nigroviridis	81.06	0.00e+00	1008.00
IUUC-Tbe-128141	Tupaia belangeri	78.05	0.00e+00	815.00
IUUC-Ttr-128908	Tursiops truncatus	93.91	0.00e+00	651.00
IUUC-Xtr-132272	Xenopus tropicalis	71.58	0.00e+00	1167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence