iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011515

Ensembl Protein ID

ENSAMXP00000007338.1

UniProt Accession

W5KIC6; W5KIC6_ASTMX

Genbank Protein ID

ENSAMXP00000007338

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01084443

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000007105.1	ENSAMXT00000007338.1	ENSAMXP00000007338.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-27	94.5	1573	1607
UBD/Beta-Prp	4.40e-43	147.8	1329	1570

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++la+ ++ ++l+s+++ g +kvW+++ ++
   Q: 1573 HKDWVCALAYvPGrPMLLSACRGGMLKVWNVDNFT 1607
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdlet.gqcl 129
           +++  +gh+++v +++  ++  +l tgs+Drt k w+l tg+ ++tl+gh ++v+s++++ ++  lv + + ++i+vwd++   +c+
   Q: 1329 CVAMAEGHSKPVLCLDATDE--LLFTGSKDRTCKMWNLVTGQEIVTLRGHPNNVVSVKYCVNS-GLVFTVSTSYIKVWDIRDsAKCV 1412
           566679**********9999..9**************************************55.445555578*******9615777 PP
   S: 130  ee.....................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng... 192
           ++                     t ++ +  +n ++++p+g++l ++ + +tvr Wdl++++   +ltg h +sv +l++ ++g   
   Q: 1413 RTftssgqvvsgdacagtttrtiTTTQGEYQINQIALNPSGSVLYAA-AGNTVRTWDLNRMQATGKLTG-HIGSVMCLTVGYSGggk 1497
           77********************988888889999*****88544443.4579****************9.*********87777778 PP
   S: 193  kelvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlq 261
            ++++gs+d +vk++d+ +g   ++  +h+      d + +++++  ++ l sgs D+ i+ Wdl++++l++++ 
   Q: 1498 DQVITGSKDHYVKIFDVAEGAQGNIGPAHNfepphyDGIECLAVH--GDVLFSGSRDNGIKKWDLEQQELIQQIP 1570
           99****************999988888888888888*********..**********************999876 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

LFLTLKSFVR ISSRIRPQMA KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY DFVFDIDAHQ 60
QQIYGSCVHK LIEGCFEGYN ATVFAYGQTG SGKTYTMGTG FDVNVGEEEQ GIIPRAVRQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTTTTAA CATTAAAATC GTTTGTTCGT ATCTCTTCCA GGATTCGGCC TCAGATGGCC 60
AAAGAGAAGA TCGAAGGCTG CCACATCTGC ACCTCAGTGA CCCCAGGAGA GCCCCAGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	74.93	0.00e+00	1372.00
IUUC-Apl-003204	Anas platyrhynchos	75.71	0.00e+00	758.00
IUUC-Aca-004506	Anolis carolinensis	74.11	0.00e+00	1413.00
IUUC-Bta-013185	Bos taurus	66.55	0.00e+00	689.00
IUUC-Cja-018844	Callithrix jacchus	75.56	0.00e+00	1420.00
IUUC-Cfa-021187	Canis familiaris	75.86	0.00e+00	1424.00
IUUC-Csa-023852	Chlorocebus sabaeus	75.59	0.00e+00	1425.00
IUUC-Csv-026158	Ciona savignyi	52.34	3.00e-178	619.00
IUUC-Dre-027839	Danio rerio	84.93	0.00e+00	2650.00
IUUC-Dno-030058	Dasypus novemcinctus	72.93	0.00e+00	1335.00
IUUC-Dor-030673	Dipodomys ordii	75.59	0.00e+00	1407.00
IUUC-Ete-032705	Echinops telfairi	67.52	0.00e+00	723.00
IUUC-Eca-033885	Equus caballus	74.53	0.00e+00	1375.00
IUUC-Eeu-035338	Erinaceus europaeus	57.00	0.00e+00	869.00
IUUC-Fca-035388	Felis catus	75.79	0.00e+00	1429.00
IUUC-Fal-037044	Ficedula albicollis	75.62	0.00e+00	1478.00
IUUC-Gmo-039034	Gadus morhua	71.79	0.00e+00	1338.00
IUUC-Gac-041328	Gasterosteus aculeatus	77.90	0.00e+00	2460.00
IUUC-Ggo-045392	Gorilla gorilla	75.15	0.00e+00	1414.00
IUUC-Hsa-046713	Homo sapiens	75.69	0.00e+00	1425.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	74.68	0.00e+00	1296.00
IUUC-Lch-049786	Latimeria chalumnae	74.98	0.00e+00	2318.00
IUUC-Loc-052703	Lepisosteus oculatus	83.87	0.00e+00	2626.00
IUUC-Laf-054193	Loxodonta africana	69.09	0.00e+00	1275.00
IUUC-Mcc-055484	Macaca mulatta	73.99	0.00e+00	1410.00
IUUC-Meu-056278	Macropus eugenii	69.68	0.00e+00	976.00
IUUC-Mga-059816	Meleagris gallopavo	72.17	0.00e+00	1377.00
IUUC-Mmr-061071	Microcebus murinus	72.74	0.00e+00	1399.00
IUUC-Mdo-062845	Monodelphis domestica	76.34	0.00e+00	1420.00
IUUC-Mmu-063967	Mus musculus	75.49	0.00e+00	1403.00
IUUC-Mpu-066448	Mustela putorius furo	74.41	0.00e+00	1411.00
IUUC-Mlu-067599	Myotis lucifugus	53.07	0.00e+00	1001.00
IUUC-Nle-070037	Nomascus leucogenys	75.98	0.00e+00	1432.00
IUUC-Opr-070325	Ochotona princeps	73.15	0.00e+00	1365.00
IUUC-Ont-071851	Oreochromis niloticus	79.11	0.00e+00	2493.00
IUUC-Oan-073615	Ornithorhynchus anatinus	76.08	0.00e+00	1431.00
IUUC-Ola-086703	Oryzias latipes	78.18	0.00e+00	2452.00
IUUC-Oga-088171	Otolemur garnettii	72.84	0.00e+00	1328.00
IUUC-Ptr-090535	Pan troglodytes	74.78	0.00e+00	1413.00
IUUC-Pan-091917	Papio anubis	73.94	0.00e+00	1212.00
IUUC-Psi-093752	Pelodiscus sinensis	67.84	0.00e+00	1180.00
IUUC-Pfo-096827	Poecilia formosa	76.52	0.00e+00	2379.00
IUUC-Pab-098441	Pongo abelii	75.79	0.00e+00	1428.00
IUUC-Pca-100781	Procavia capensis	80.31	0.00e+00	769.00
IUUC-Pva-103099	Pteropus vampyrus	72.33	0.00e+00	1042.00
IUUC-Rno-105872	Rattus norvegicus	75.30	0.00e+00	1431.00
IUUC-Ssc-115638	Sus scrofa	74.10	0.00e+00	1113.00
IUUC-Tru-118242	Takifugu rubripes	77.71	0.00e+00	2523.00
IUUC-Ttr-128824	Tursiops truncatus	71.99	0.00e+00	1328.00
IUUC-Xtr-131798	Xenopus tropicalis	60.85	0.00e+00	1101.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence