iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033885

Ensembl Protein ID

ENSECAP00000022324.1

UniProt Accession

F6RL77; F6RL77_HORSE

Protein Name

Uncharacterized protein

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024729.1	ENSECAT00000026727.1	ENSECAP00000022324.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-30	104.1	1532	1566
UBD/Beta-Prp	5.50e-41	140.8	1400	1602

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g+ikvW+++ ++
   Q: 1532 HKDWVCALAFvPGrPMLLSACRAGVIKVWNVDNFT 1566
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirv..wdletgqclee. 131
            e +++++ +sp+g +++ +++ +++++w+ls +++v +l+gh   v++l++ +   + d +v+Gs+d +++   w    g+c+   
   Q: 1400 GEHQINQIALSPSG-TMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQtasQHDLVVTGSKDHYVKAvlW----GECVAGt 1481
           4567*********9.999************************************98556*************9889....7777667 PP
   S: 132  .....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtge 213
                ++ +h + + c+++++  ++l+sGs D+ ++ Wdl++++l+++   +h+d v  l+f + ++ l+s+ + g +k+w++ + +
   Q: 1482 ipthnFEPPHYDGIECLAIQG--DILFSGSRDNGIKKWDLEQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRAGVIKVWNVDNFT 1566
           77799999************9..**************************999*********************************** PP
   S: 214  cvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
            + + +gh+++++ + +    +++ ++ssD  +++W++
   Q: 1567 PIGEIKGHDSPINAICTN--AKHIFTASSDCRVKLWNY 1602
           *************87777..****************96 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

VSGRIRPQLS KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY DFVFDLDTWQ ERIYSTCVDK 60
LIEGCFDGYN ATVLAYGQTG AGKTYTMGTG FDMATSEEEQ GIIPRAIAHL FGGIAERKRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTCGGGCA GGATCCGGCC TCAGCTGTCA AAGGAGAAGA TTGAGGGCTG TCACATCTGC 60
ACCTCGGTCA CCCCGGGGGA GCCCCAGGTC CTCCTGGGGA AGGACAAGGC CTTCACCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	95.58	0.00e+00	2758.00
IUUC-Apl-003204	Anas platyrhynchos	74.98	0.00e+00	1537.00
IUUC-Aca-004506	Anolis carolinensis	79.60	0.00e+00	1590.00
IUUC-Ame-011515	Astyanax mexicanus	74.90	0.00e+00	1419.00
IUUC-Bta-013185	Bos taurus	75.09	0.00e+00	2073.00
IUUC-Cja-018844	Callithrix jacchus	93.00	0.00e+00	2758.00
IUUC-Cfa-021187	Canis familiaris	96.31	0.00e+00	2799.00
IUUC-Cpo-022444	Cavia porcellus	93.60	0.00e+00	2785.00
IUUC-Csa-023852	Chlorocebus sabaeus	96.31	0.00e+00	2812.00
IUUC-Dre-027839	Danio rerio	74.45	0.00e+00	1412.00
IUUC-Dno-030058	Dasypus novemcinctus	91.63	0.00e+00	2715.00
IUUC-Dor-030673	Dipodomys ordii	91.28	0.00e+00	2612.00
IUUC-Ete-032705	Echinops telfairi	82.87	0.00e+00	885.00
IUUC-Eeu-035338	Erinaceus europaeus	93.94	0.00e+00	1127.00
IUUC-Fca-035388	Felis catus	96.75	0.00e+00	2645.00
IUUC-Fal-037044	Ficedula albicollis	86.61	0.00e+00	2657.00
IUUC-Gmo-039034	Gadus morhua	67.87	0.00e+00	1231.00
IUUC-Gac-041328	Gasterosteus aculeatus	72.13	0.00e+00	2236.00
IUUC-Ggo-045392	Gorilla gorilla	95.83	0.00e+00	2799.00
IUUC-Hsa-046713	Homo sapiens	96.43	0.00e+00	2813.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	96.80	0.00e+00	1667.00
IUUC-Loc-052703	Lepisosteus oculatus	79.15	0.00e+00	2439.00
IUUC-Laf-054193	Loxodonta africana	85.96	0.00e+00	2446.00
IUUC-Mcc-055484	Macaca mulatta	95.37	0.00e+00	2794.00
IUUC-Meu-056278	Macropus eugenii	85.52	0.00e+00	1184.00
IUUC-Mga-059816	Meleagris gallopavo	83.01	0.00e+00	2517.00
IUUC-Mmr-061071	Microcebus murinus	91.86	0.00e+00	2708.00
IUUC-Mdo-062845	Monodelphis domestica	90.11	0.00e+00	2716.00
IUUC-Mmu-063967	Mus musculus	94.53	0.00e+00	2732.00
IUUC-Mpu-066448	Mustela putorius furo	95.01	0.00e+00	2790.00
IUUC-Nle-070037	Nomascus leucogenys	94.77	0.00e+00	2169.00
IUUC-Opr-070325	Ochotona princeps	91.23	0.00e+00	2617.00
IUUC-Ont-071851	Oreochromis niloticus	72.49	0.00e+00	2244.00
IUUC-Oan-073615	Ornithorhynchus anatinus	87.61	0.00e+00	2485.00
IUUC-Ocu-073855	Oryctolagus cuniculus	95.08	0.00e+00	2746.00
IUUC-Ola-086703	Oryzias latipes	71.68	0.00e+00	2236.00
IUUC-Oga-088171	Otolemur garnettii	93.38	0.00e+00	2749.00
IUUC-Oar-089693	Ovis aries	74.21	0.00e+00	2019.00
IUUC-Ptr-090535	Pan troglodytes	94.83	0.00e+00	1766.00
IUUC-Pan-091917	Papio anubis	96.07	0.00e+00	2587.00
IUUC-Psi-093752	Pelodiscus sinensis	78.43	0.00e+00	1389.00
IUUC-Pfo-096827	Poecilia formosa	69.10	0.00e+00	1319.00
IUUC-Pab-098441	Pongo abelii	96.43	0.00e+00	2828.00
IUUC-Pca-100781	Procavia capensis	95.81	0.00e+00	904.00
IUUC-Pva-103099	Pteropus vampyrus	90.40	0.00e+00	1328.00
IUUC-Rno-105872	Rattus norvegicus	94.34	0.00e+00	2775.00
IUUC-Sha-107097	Sarcophilus harrisii	88.83	0.00e+00	2600.00
IUUC-Ssc-115638	Sus scrofa	94.22	0.00e+00	2438.00
IUUC-Tgu-116504	Taeniopygia guttata	86.22	0.00e+00	1664.00
IUUC-Tru-118242	Takifugu rubripes	72.44	0.00e+00	2246.00
IUUC-Ttr-128824	Tursiops truncatus	87.35	0.00e+00	2210.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence