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Tag Content
iUUCD ID IUUC-Vvi-131312
Ensembl Protein ID VIT_08s0056g00830.t01
UniProt Accession F6HMV3; F6HMV3_VITVI
Genbank Protein ID CCB55978.1
Protein Name Presenilin
Genbank Nucleotide ID FN595995
Gene Name PS1; VIT_08s0056g00830
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
VIT_08s0056g00830 VIT_08s0056g00830.t01 VIT_08s0056g00830.t01
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/CUE 31.92 2.00e-39 159.00 IUUC-Cel-018553
UBD/Alpha-Helix/CUE 33.67 5.00e-29 126.00 IUUC-Dre-028689
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Vitis vinifera
Functional Description
(View)

Functional Description



     Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
Protein Sequence
(Fasta)
MDSSILDSLG VEIIGVMSPV SVCMLLVVLL VYTLSSATSS AASDTIRTAA NLVYLESPSD 60
STTQKLEGAL LNALVFIVLI AIVTFVLVLL YYYNFTNFLK NYMRFSAFFV LGTMGGSIFL 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Vvi-131312|UBD,CUE|Vitis vinifera
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCATGGATTC GAGCATTCTC GATTCTCTCG GAGTCGAAAT CATTGGCGTG ATGTCGCCGG 60
TCTCAGTCTG CATGCTCCTG GTGGTTCTCC TCGTTTACAC CCTCTCCTCC GCCACCTCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Vvi-131312|UBD,CUE|Vitis vinifera
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005887--C:integral component of plasma membrane
GO:0005634--C:nucleus
GO:0004190--F:aspartic-type endopeptidase activity
GO:0004175--F:endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

KEGG vvi:100263915
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000686 Aegilops tauschii 53.16 2.00e-83 303.00
IUUC-Aml-001648 Ailuropoda melanoleuca 38.79 9.00e-36 143.00
IUUC-Atr-003039 Amborella trichopoda 61.80 9.00e-134 469.00
IUUC-Apl-003959 Anas platyrhynchos 30.43 1.00e-22 99.80
IUUC-Aca-004582 Anolis carolinensis 33.91 4.00e-34 138.00
IUUC-Aly-005455 Arabidopsis lyrata 64.83 2.00e-136 477.00
IUUC-Ath-006730 Arabidopsis thaliana 64.69 2.00e-137 481.00
IUUC-Ame-010686 Astyanax mexicanus 33.25 1.00e-34 139.00
IUUC-Bta-013026 Bos taurus 35.15 8.00e-36 143.00
IUUC-Bdi-014196 Brachypodium distachyon 53.76 4.00e-96 344.00
IUUC-Bol-015841 Brassica oleracea 67.03 3.00e-128 450.00
IUUC-Bra-017580 Brassica rapa 82.51 2.00e-66 244.00
IUUC-Cel-018553 Caenorhabditis elegans 32.07 1.00e-42 166.00
IUUC-Cja-019994 Callithrix jacchus 35.16 4.00e-37 148.00
IUUC-Cfa-020074 Canis familiaris 34.66 1.00e-35 143.00
IUUC-Cpo-022237 Cavia porcellus 35.16 3.00e-36 145.00
IUUC-Cre-022747 Chlamydomonas reinhardtii 46.28 8.00e-48 184.00
IUUC-Csa-023537 Chlorocebus sabaeus 35.66 1.00e-36 146.00
IUUC-Cho-024735 Choloepus hoffmanni 36.42 4.00e-37 148.00
IUUC-Cin-025780 Ciona intestinalis 33.50 1.00e-40 159.00
IUUC-Csv-025967 Ciona savignyi 33.42 1.00e-40 159.00
IUUC-Dre-028689 Danio rerio 33.42 6.00e-31 127.00
IUUC-Dno-029758 Dasypus novemcinctus 34.16 7.00e-35 140.00
IUUC-Dor-030609 Dipodomys ordii 41.32 2.00e-19 89.40
IUUC-Dme-031929 Drosophila melanogaster 31.63 3.00e-39 155.00
IUUC-Ete-032487 Echinops telfairi 35.08 2.00e-17 82.80
IUUC-Eca-034387 Equus caballus 35.35 9.00e-27 113.00
IUUC-Eeu-035134 Erinaceus europaeus 37.04 2.00e-35 142.00
IUUC-Fca-036243 Felis catus 35.91 3.00e-36 145.00
IUUC-Fal-036600 Ficedula albicollis 35.80 3.00e-33 135.00
IUUC-Gmo-038550 Gadus morhua 33.17 2.00e-23 102.00
IUUC-Gga-040993 Gallus gallus 34.32 1.00e-34 140.00
IUUC-Gac-042511 Gasterosteus aculeatus 32.75 2.00e-35 142.00
IUUC-Gma-043822 Glycine max 67.35 2.00e-52 198.00
IUUC-Ggo-044859 Gorilla gorilla 37.50 3.00e-23 101.00
IUUC-Hsa-046822 Homo sapiens 35.66 9.00e-37 147.00
IUUC-Hvu-047141 Hordeum vulgare 54.33 1.00e-90 326.00
IUUC-Itr-048420 Ictidomys tridecemlineatus 36.64 2.00e-37 148.00
IUUC-Lch-049638 Latimeria chalumnae 36.67 5.00e-27 114.00
IUUC-Lpe-051132 Leersia perrieri 52.64 3.00e-92 331.00
IUUC-Loc-052427 Lepisosteus oculatus 32.41 6.00e-39 154.00
IUUC-Laf-053979 Loxodonta africana 36.45 9.00e-31 127.00
IUUC-Mcc-055682 Macaca mulatta 35.66 9.00e-37 147.00
IUUC-Meu-056004 Macropus eugenii 36.46 1.00e-22 99.80
IUUC-Mtr-058392 Medicago truncatula 63.62 4.00e-120 423.00
IUUC-Mga-059466 Meleagris gallopavo 33.66 5.00e-34 137.00
IUUC-Mmr-060890 Microcebus murinus 35.48 5.00e-26 111.00
IUUC-Mdo-062122 Monodelphis domestica 35.07 3.00e-36 145.00
IUUC-Mmu-063823 Mus musculus 35.35 8.00e-27 114.00
IUUC-Mac-064858 Musa acuminata 88.89 6.00e-42 163.00
IUUC-Mpu-065927 Mustela putorius furo 35.41 2.00e-35 142.00
IUUC-Mlu-067079 Myotis lucifugus 35.16 1.00e-40 160.00
IUUC-Nle-070180 Nomascus leucogenys 35.66 9.00e-37 147.00
IUUC-Opr-070847 Ochotona princeps 37.91 7.00e-22 97.40
IUUC-Ont-071846 Oreochromis niloticus 34.95 3.00e-21 95.50
IUUC-Oan-072783 Ornithorhynchus anatinus 37.77 1.00e-33 135.00
IUUC-Ocu-074527 Oryctolagus cuniculus 35.91 2.00e-34 139.00
IUUC-Oba-075256 Oryza barthii 51.21 8.00e-83 299.00
IUUC-Obr-076302 Oryza brachyantha 51.52 2.00e-90 325.00
IUUC-Ogl-077097 Oryza glaberrima 51.16 3.00e-90 324.00
IUUC-Ogu-078570 Oryza glumaepatula 53.10 5.00e-90 323.00
IUUC-Oin-079244 Oryza indica 51.92 5.00e-90 323.00
IUUC-Olo-080484 Oryza longistaminata 49.68 2.00e-61 228.00
IUUC-Ome-081814 Oryza meridionalis 51.63 1.00e-91 329.00
IUUC-Oni-082057 Oryza nivara 51.89 7.00e-86 310.00
IUUC-Opu-084176 Oryza punctata 54.37 7.00e-92 330.00
IUUC-Oru-084618 Oryza rufipogon 53.33 4.00e-90 324.00
IUUC-Osa-085602 Oryza sativa 53.43 4.00e-91 327.00
IUUC-Ola-086707 Oryzias latipes 33.16 4.00e-24 104.00
IUUC-Olu-087811 Ostreococcus lucimarinus 36.18 9.00e-56 209.00
IUUC-Oga-088560 Otolemur garnettii 34.85 7.00e-26 110.00
IUUC-Oar-090348 Ovis aries 34.90 1.00e-36 146.00
IUUC-Ptr-091060 Pan troglodytes 35.66 9.00e-37 147.00
IUUC-Pan-091855 Papio anubis 37.50 1.00e-22 99.80
IUUC-Psi-093505 Pelodiscus sinensis 33.83 1.00e-35 143.00
IUUC-Pma-094612 Petromyzon marinus 42.06 2.00e-20 92.80
IUUC-Ppa-095431 Physcomitrella patens 45.35 2.00e-88 318.00
IUUC-Pfo-097396 Poecilia formosa 31.92 3.00e-35 142.00
IUUC-Pab-098591 Pongo abelii 35.66 9.00e-37 147.00
IUUC-Pop-099661 Populus trichocarpa 49.89 1.00e-85 309.00
IUUC-Pca-101120 Procavia capensis 35.36 8.00e-22 97.40
IUUC-Ppe-101495 Prunus persica 74.41 2.00e-163 567.00
IUUC-Pva-102244 Pteropus vampyrus 34.09 1.00e-35 143.00
IUUC-Rno-105861 Rattus norvegicus 34.58 5.00e-22 98.20
IUUC-Sha-107045 Sarcophilus harrisii 35.57 1.00e-36 146.00
IUUC-Smo-109325 Selaginella moellendorffii 45.96 5.00e-64 237.00
IUUC-Sit-110624 Setaria italica 50.62 4.00e-87 314.00
IUUC-Sly-110865 Solanum lycopersicum 88.57 1.00e-32 130.00
IUUC-Stu-112433 Solanum tuberosum 65.08 2.00e-121 427.00
IUUC-Sar-113169 Sorex araneus 37.15 9.00e-34 137.00
IUUC-Sbi-114305 Sorghum bicolor 54.24 9.00e-90 323.00
IUUC-Ssc-115766 Sus scrofa 34.66 3.00e-36 145.00
IUUC-Tgu-116469 Taeniopygia guttata 36.65 5.00e-34 137.00
IUUC-Tru-117732 Takifugu rubripes 31.92 4.00e-31 128.00
IUUC-Tsy-119624 Tarsius syrichta 45.79 5.00e-22 98.20
IUUC-Tni-119852 Tetraodon nigroviridis 33.01 3.00e-30 125.00
IUUC-Tca-121865 Theobroma cacao 75.27 2.00e-150 525.00
IUUC-Tae-123984 Triticum aestivum 53.65 4.00e-89 320.00
IUUC-Tur-126237 Triticum urartu 53.08 2.00e-83 301.00
IUUC-Tbe-128148 Tupaia belangeri 45.79 2.00e-22 99.00
IUUC-Ttr-128793 Tursiops truncatus 38.23 2.00e-33 135.00
IUUC-Vpa-130625 Vicugna pacos 36.02 7.00e-31 127.00
IUUC-Xtr-132756 Xenopus tropicalis 32.35 9.00e-28 117.00
IUUC-Xma-133377 Xiphophorus maculatus 31.76 7.00e-33 134.00
Created Date 25-Jun-2017

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