iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090405

Ensembl Protein ID

ENSOARP00000022205.1

UniProt Accession

W5QHK5; W5QHK5_SHEEP

Genbank Protein ID

ENSOARP00000022205

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Genbank Nucleotide ID

AMGL01009335

Gene Name

DCUN1D1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020662.1	ENSOART00000022510.1	ENSOARP00000022205.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	2.20e-91	305.3	60	246
UBD/Alpha-Helix/UBA	3.90e-07	30.2	6	44

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselk 89
           ++kkle+l++rYkdpq++ +igi+g+++fc+dl++dp++i+vL++awk++aat+cefs++ef+dg+t+lgcdsiekl+++++++e+elk
   Q: 60   DRKKLEQLYSRYKDPQDEnKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELK 148
           78**************999********************************************************************** PP
   S: 90   deqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWP 178
           +  +fkd+Y+f+fnfak++gqk+ldl++aia+w+L+l++r fk+ld+w+kfL e++k+si+kDtWnllL+fs++ia+d+snYdeegaWP
   Q: 149  EPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGR-FKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWP 236
           ***************************************9.************************************************ PP
   S: 179  vliDefveyl 188
           vliD+fve++
   Q: 237  VLIDDFVEFA 246
           ********97 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlve.MGFdreealqaLraannnleaAveyLl 39
           +++dk++q++  +  ++++a+ +L ++++ l++A+++++
   Q: 6    SQKDKVRQFMIfTQSSEKTAVSCLSQNDWKLDVATDNFF 44
           699********9999999*******************99 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

NKLKSSQKDK VRQFMIFTQS SEKTAVSCLS QNDWKLDVAT DNFFQNPELY IRESVKGSLD 60
RKKLEQLYSR YKDPQDENKI GIDGIQQFCD DLALDPASIS VLIIAWKFRA ATQCEFSKQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAAGTTGA AATCATCGCA GAAGGATAAA GTTCGTCAGT TTATGATCTT CACACAATCT 60
AGTGAAAAAA CAGCAGTAAG TTGTCTGTCT CAAAATGACT GGAAGTTAGA TGTTGCAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	43.50	1.00e-60	226.00
IUUC-Aml-001879	Ailuropoda melanoleuca	99.22	3.00e-152	530.00
IUUC-Atr-002662	Amborella trichopoda	38.69	5.00e-25	107.00
IUUC-Apl-003451	Anas platyrhynchos	97.32	8.00e-150	522.00
IUUC-Aca-005269	Anolis carolinensis	95.74	5.00e-148	516.00
IUUC-Aly-006285	Arabidopsis lyrata	38.21	4.00e-44	171.00
IUUC-Ath-007531	Arabidopsis thaliana	43.50	3.00e-57	214.00
IUUC-Ago-007806	Ashbya gossypii	23.74	2.00e-20	92.40
IUUC-Acl-008172	Aspergillus clavatus	27.38	6.00e-23	100.00
IUUC-Afl-008569	Aspergillus flavus	29.37	5.00e-29	120.00
IUUC-Ani-009241	Aspergillus nidulans	26.71	6.00e-25	107.00
IUUC-Ang-009664	Aspergillus niger	28.40	8.00e-24	103.00
IUUC-Ate-010414	Aspergillus terreus	30.23	2.00e-30	125.00
IUUC-Ame-011763	Astyanax mexicanus	88.37	5.00e-136	476.00
IUUC-Bgr-011991	Blumeria graminis	32.23	1.00e-25	110.00
IUUC-Bta-013561	Bos taurus	100.00	3.00e-145	506.00
IUUC-Bci-013824	Botrytis cinerea	32.68	7.00e-31	127.00
IUUC-Bdi-014138	Brachypodium distachyon	43.09	9.00e-61	226.00
IUUC-Bol-016110	Brassica oleracea	43.09	1.00e-56	213.00
IUUC-Bra-017111	Brassica rapa	43.09	2.00e-56	212.00
IUUC-Cel-018441	Caenorhabditis elegans	36.13	2.00e-50	192.00
IUUC-Cja-019502	Callithrix jacchus	99.22	4.00e-152	530.00
IUUC-Cfa-020523	Canis familiaris	99.59	1.00e-144	504.00
IUUC-Cpo-022196	Cavia porcellus	98.45	3.00e-151	526.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	36.50	5.00e-50	191.00
IUUC-Csa-023551	Chlorocebus sabaeus	99.61	1.00e-152	531.00
IUUC-Cho-024373	Choloepus hoffmanni	97.67	2.00e-145	508.00
IUUC-Cin-025269	Ciona intestinalis	60.70	2.00e-98	352.00
IUUC-Csv-026372	Ciona savignyi	41.41	2.00e-50	191.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	28.80	4.00e-23	100.00
IUUC-Cne-026950	Cryptococcus neoformans	31.23	5.00e-30	124.00
IUUC-Dre-028247	Danio rerio	88.37	2.00e-136	478.00
IUUC-Dno-028974	Dasypus novemcinctus	99.61	1.00e-152	531.00
IUUC-Dor-030696	Dipodomys ordii	88.76	7.00e-132	462.00
IUUC-Dse-031365	Dothistroma septosporum	27.52	2.00e-25	109.00
IUUC-Dme-032197	Drosophila melanogaster	63.71	2.00e-92	331.00
IUUC-Ete-032371	Echinops telfairi	99.22	2.00e-152	530.00
IUUC-Eca-033242	Equus caballus	99.61	1.00e-152	531.00
IUUC-Eeu-035317	Erinaceus europaeus	99.22	2.00e-152	531.00
IUUC-Fca-036061	Felis catus	99.61	1.00e-152	531.00
IUUC-Fal-037372	Ficedula albicollis	97.32	1.00e-149	521.00
IUUC-Fox-037884	Fusarium oxysporum	31.54	4.00e-18	84.00
IUUC-Fso-038150	Fusarium solani	28.92	4.00e-20	91.70
IUUC-Gmo-038885	Gadus morhua	87.98	5.00e-136	476.00
IUUC-Gga-040935	Gallus gallus	98.45	2.00e-151	527.00
IUUC-Gac-041937	Gasterosteus aculeatus	87.60	1.00e-134	471.00
IUUC-Gma-043545	Glycine max	42.28	3.00e-57	214.00
IUUC-Ggo-044468	Gorilla gorilla	98.46	2.00e-150	524.00
IUUC-Hsa-046089	Homo sapiens	99.61	1.00e-152	531.00
IUUC-Hvu-047636	Hordeum vulgare	39.02	2.00e-22	98.60
IUUC-Itr-047902	Ictidomys tridecemlineatus	75.39	2.00e-120	424.00
IUUC-Kpa-049127	Komagataella pastoris	28.12	2.00e-21	95.50
IUUC-Lch-050600	Latimeria chalumnae	94.57	5.00e-147	513.00
IUUC-Lpe-051540	Leersia perrieri	43.90	7.00e-61	226.00
IUUC-Loc-052509	Lepisosteus oculatus	94.19	2.00e-144	504.00
IUUC-Lma-053103	Leptosphaeria maculans	31.18	4.00e-32	131.00
IUUC-Laf-053527	Loxodonta africana	98.84	4.00e-152	530.00
IUUC-Mcc-055699	Macaca mulatta	89.55	3.00e-146	510.00
IUUC-Meu-056626	Macropus eugenii	77.91	1.00e-111	395.00
IUUC-Mor-056909	Magnaporthe oryzae	27.82	2.00e-25	108.00
IUUC-Mpo-057299	Magnaporthe poae	25.00	2.00e-17	82.40
IUUC-Mtr-057964	Medicago truncatula	41.46	1.00e-56	212.00
IUUC-Mla-058990	Melampsora laricipopulina	27.92	2.00e-18	86.70
IUUC-Mga-059379	Meleagris gallopavo	98.28	7.00e-136	475.00
IUUC-Mvi-060312	Microbotryum violaceum	34.23	1.00e-41	163.00
IUUC-Mmr-060851	Microcebus murinus	99.61	2.00e-152	530.00
IUUC-Mdo-063074	Monodelphis domestica	99.22	5.00e-155	541.00
IUUC-Mmu-063954	Mus musculus	99.22	1.00e-152	531.00
IUUC-Mac-065016	Musa acuminata	44.44	3.00e-43	167.00
IUUC-Mpu-066870	Mustela putorius furo	99.59	1.00e-144	504.00
IUUC-Mlu-067701	Myotis lucifugus	99.22	9.00e-152	528.00
IUUC-Ncr-068780	Neurospora crassa	25.45	2.00e-23	102.00
IUUC-Nle-069291	Nomascus leucogenys	99.61	1.00e-152	531.00
IUUC-Opr-070265	Ochotona princeps	72.48	3.00e-95	340.00
IUUC-Ont-071408	Oreochromis niloticus	88.37	5.00e-135	473.00
IUUC-Oan-073031	Ornithorhynchus anatinus	99.22	4.00e-152	530.00
IUUC-Ocu-074648	Oryctolagus cuniculus	99.61	1.00e-152	531.00
IUUC-Oba-074993	Oryza barthii	43.90	5.00e-61	227.00
IUUC-Obr-076341	Oryza brachyantha	43.50	3.00e-61	228.00
IUUC-Ogl-077099	Oryza glaberrima	43.90	5.00e-61	227.00
IUUC-Ogu-078285	Oryza glumaepatula	43.50	8.00e-60	223.00
IUUC-Oin-079441	Oryza indica	43.90	7.00e-61	226.00
IUUC-Olo-081037	Oryza longistaminata	43.90	7.00e-61	226.00
IUUC-Ome-081357	Oryza meridionalis	43.90	7.00e-61	226.00
IUUC-Oni-082632	Oryza nivara	43.50	6.00e-61	226.00
IUUC-Opu-083351	Oryza punctata	43.53	6.00e-57	213.00
IUUC-Oru-084306	Oryza rufipogon	43.90	7.00e-61	226.00
IUUC-Osa-085307	Oryza sativa	43.90	7.00e-61	226.00
IUUC-Ola-086371	Oryzias latipes	83.72	2.00e-133	468.00
IUUC-Olu-087646	Ostreococcus lucimarinus	36.44	2.00e-44	172.00
IUUC-Oga-089015	Otolemur garnettii	100.00	4.00e-153	533.00
IUUC-Ptr-090735	Pan troglodytes	99.61	1.00e-152	531.00
IUUC-Pan-092186	Papio anubis	98.84	3.00e-149	520.00
IUUC-Psi-093110	Pelodiscus sinensis	98.77	6.00e-143	499.00
IUUC-Pno-095145	Phaeosphaeria nodorum	32.54	9.00e-25	107.00
IUUC-Ppa-095306	Physcomitrella patens	43.15	4.00e-58	218.00
IUUC-Pfo-096813	Poecilia formosa	83.40	1.00e-131	462.00
IUUC-Pab-098197	Pongo abelii	78.10	2.00e-118	417.00
IUUC-Pca-100218	Procavia capensis	95.74	4.00e-149	520.00
IUUC-Ppe-102032	Prunus persica	43.55	4.00e-60	224.00
IUUC-Pva-102983	Pteropus vampyrus	93.80	2.00e-138	484.00
IUUC-Pgr-103633	Puccinia graminis	27.18	4.00e-24	104.00
IUUC-Ptt-103979	Puccinia triticina	38.81	2.00e-04	40.00
IUUC-Pyt-104428	Pyrenophora triticirepentis	30.56	6.00e-29	120.00
IUUC-Rno-105554	Rattus norvegicus	98.45	5.00e-152	529.00
IUUC-Sce-106358	Saccharomyces cerevisiae	25.37	4.00e-20	91.70
IUUC-Sha-106888	Sarcophilus harrisii	99.22	2.00e-152	531.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	30.65	7.00e-23	100.00
IUUC-Spo-108207	Schizosaccharomyces pombe	32.98	4.00e-25	108.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	33.33	1.00e-32	132.00
IUUC-Smo-108750	Selaginella moellendorffii	42.28	5.00e-50	190.00
IUUC-Sit-110052	Setaria italica	42.74	5.00e-61	227.00
IUUC-Sly-111489	Solanum lycopersicum	44.31	1.00e-59	222.00
IUUC-Stu-112517	Solanum tuberosum	43.32	7.00e-59	220.00
IUUC-Sar-113509	Sorex araneus	75.19	4.00e-106	377.00
IUUC-Sbi-114113	Sorghum bicolor	42.74	5.00e-61	227.00
IUUC-Sre-115221	Sporisorium reilianum	27.74	2.00e-25	109.00
IUUC-Ssc-115547	Sus scrofa	99.61	1.00e-152	531.00
IUUC-Tgu-117147	Taeniopygia guttata	98.45	2.00e-151	527.00
IUUC-Tru-117740	Takifugu rubripes	85.66	9.00e-133	465.00
IUUC-Tsy-119599	Tarsius syrichta	99.22	3.00e-152	530.00
IUUC-Tni-120315	Tetraodon nigroviridis	80.86	1.00e-129	455.00
IUUC-Tca-121033	Theobroma cacao	43.50	3.00e-58	218.00
IUUC-Tre-121986	Trichoderma reesei	25.96	3.00e-19	89.00
IUUC-Tvi-122607	Trichoderma virens	28.95	1.00e-25	109.00
IUUC-Tae-125740	Triticum aestivum	37.28	9.00e-55	206.00
IUUC-Tur-126375	Triticum urartu	34.70	5.00e-51	194.00
IUUC-Tme-126878	Tuber melanosporum	33.60	6.00e-39	154.00
IUUC-Ttr-129086	Tursiops truncatus	88.76	7.00e-132	462.00
IUUC-Uma-129364	Ustilago maydis	29.70	5.00e-34	137.00
IUUC-Vda-129929	Verticillium dahliae	29.29	2.00e-19	89.70
IUUC-Vpa-130048	Vicugna pacos	86.43	3.00e-127	447.00
IUUC-Vvi-130834	Vitis vinifera	44.72	5.00e-60	224.00
IUUC-Xtr-131888	Xenopus tropicalis	98.06	6.00e-151	526.00
IUUC-Xma-133580	Xiphophorus maculatus	83.72	2.00e-133	467.00
IUUC-Yli-134595	Yarrowia lipolytica	32.51	7.00e-36	143.00
IUUC-Zma-135642	Zea mays	43.67	9.00e-61	226.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence