iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000016006.3	ENSXETT00000034934.3	ENSXETP00000034934.3
ENSXETG00000016006.3	ENSXETT00000034947.3	ENSXETP00000034947.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	8.40e-18	63.7	1470	1497

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpRg 29
           ++qW+C+aC  +NeP+a+kC+ C+++++
   Q: 1470 PGQWDCDACYVRNEPSANKCVSCQNTKP 1497
           68************************98 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MRRSKAELQR YIENAQNSAT SPREKSMKGF LFARLYYEAK EYELAKRCVS SYISVQERDP 60
KAHRFLGQLF EIEGNVEKAV GCYKRSLELN PTQKDLVLRI AELICTLNIK DGRAEYWVDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCGAA GTAAAGCAGA GCTCCAGAGA TACATAGAAA ATGCGCAGAA CAGCGCGACA 60
TCACCCAGAG AGGTGAGCGG TATCATGAAT TCGCGCCCCC GGGCCTTGAA CTGTAATGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0802--TPR repeat

Interpro

IPR022011--IR1-M
IPR011993--PH_dom-like
IPR000156--Ran_bind_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001876--Znf_RanBP2

PROSITE

PS50196--RANBD1
PS50005--TPR
PS50293--TPR_REGION
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF12185--IR1-M
PF00638--Ran_BP1
PF00641--zf-RanBP

SMART

SM00160--RanBD
SM00028--TPR
SM00547--ZnF_RBZ

Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0008536--F:Ran GTPase binding
GO:0008270--F:zinc ion binding
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0043547--P:positive regulation of GTPase activity
GO:0046604--P:positive regulation of mitotic centrosome separation
GO:0006606--P:protein import into nucleus
GO:0006405--P:RNA export from nucleus
GO:0007051--P:spindle organization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002141	Ailuropoda melanoleuca	53.06	0.00e+00	1745.00
IUUC-Apl-004213	Anas platyrhynchos	55.32	0.00e+00	764.00
IUUC-Aca-005244	Anolis carolinensis	56.46	0.00e+00	2917.00
IUUC-Acl-008308	Aspergillus clavatus	23.93	2.00e-03	37.00
IUUC-Afl-008658	Aspergillus flavus	25.22	1.00e-02	34.30
IUUC-Afu-008913	Aspergillus fumigatus	23.53	7.00e-03	35.00
IUUC-Ang-009619	Aspergillus niger	31.25	1.70e-02	33.50
IUUC-Ame-011486	Astyanax mexicanus	64.27	0.00e+00	631.00
IUUC-Bta-012952	Bos taurus	56.24	0.00e+00	2483.00
IUUC-Cja-019112	Callithrix jacchus	56.66	0.00e+00	1687.00
IUUC-Cfa-020158	Canis familiaris	54.63	0.00e+00	1697.00
IUUC-Cpo-022292	Cavia porcellus	55.39	0.00e+00	2762.00
IUUC-Csa-023696	Chlorocebus sabaeus	54.28	0.00e+00	1674.00
IUUC-Cho-024560	Choloepus hoffmanni	51.04	7.00e-173	602.00
IUUC-Dre-027540	Danio rerio	46.68	0.00e+00	2201.00
IUUC-Dno-029177	Dasypus novemcinctus	54.76	0.00e+00	2726.00
IUUC-Dor-030161	Dipodomys ordii	48.11	0.00e+00	764.00
IUUC-Ete-032679	Echinops telfairi	57.31	0.00e+00	878.00
IUUC-Eca-034415	Equus caballus	56.11	0.00e+00	1687.00
IUUC-Eeu-035195	Erinaceus europaeus	51.53	0.00e+00	1717.00
IUUC-Fca-036339	Felis catus	55.97	0.00e+00	2405.00
IUUC-Fal-036665	Ficedula albicollis	54.76	0.00e+00	2806.00
IUUC-Gmo-038469	Gadus morhua	48.13	0.00e+00	2047.00
IUUC-Gga-041154	Gallus gallus	54.02	0.00e+00	2404.00
IUUC-Gac-042057	Gasterosteus aculeatus	49.33	0.00e+00	2119.00
IUUC-Hsa-046168	Homo sapiens	54.43	0.00e+00	1711.00
IUUC-Itr-049075	Ictidomys tridecemlineatus	55.14	0.00e+00	2485.00
IUUC-Lch-050060	Latimeria chalumnae	48.56	0.00e+00	1530.00
IUUC-Loc-052650	Lepisosteus oculatus	51.34	0.00e+00	2581.00
IUUC-Laf-053667	Loxodonta africana	55.85	0.00e+00	2910.00
IUUC-Mcc-055115	Macaca mulatta	54.34	0.00e+00	1698.00
IUUC-Mga-059419	Meleagris gallopavo	54.60	0.00e+00	2769.00
IUUC-Mmr-061001	Microcebus murinus	53.98	0.00e+00	1755.00
IUUC-Mdo-061922	Monodelphis domestica	53.97	0.00e+00	1384.00
IUUC-Mmu-063291	Mus musculus	55.98	0.00e+00	2858.00
IUUC-Mpu-066011	Mustela putorius furo	60.50	0.00e+00	1428.00
IUUC-Mlu-067422	Myotis lucifugus	55.14	0.00e+00	1683.00
IUUC-Nle-069190	Nomascus leucogenys	53.94	0.00e+00	1596.00
IUUC-Opr-070420	Ochotona princeps	53.22	0.00e+00	1659.00
IUUC-Ont-071362	Oreochromis niloticus	50.34	0.00e+00	2551.00
IUUC-Oan-072832	Ornithorhynchus anatinus	54.49	0.00e+00	1452.00
IUUC-Ocu-073902	Oryctolagus cuniculus	55.75	0.00e+00	2886.00
IUUC-Ola-087304	Oryzias latipes	45.17	0.00e+00	1331.00
IUUC-Oga-088196	Otolemur garnettii	56.54	0.00e+00	2931.00
IUUC-Oar-089627	Ovis aries	55.81	0.00e+00	2881.00
IUUC-Ptr-091152	Pan troglodytes	54.37	0.00e+00	1712.00
IUUC-Pan-091914	Papio anubis	54.39	0.00e+00	1698.00
IUUC-Psi-093994	Pelodiscus sinensis	57.73	0.00e+00	3004.00
IUUC-Pma-094629	Petromyzon marinus	36.52	0.00e+00	1356.00
IUUC-Pfo-096897	Poecilia formosa	47.88	0.00e+00	1268.00
IUUC-Pab-097566	Pongo abelii	55.03	0.00e+00	1363.00
IUUC-Pca-100141	Procavia capensis	49.92	0.00e+00	1647.00
IUUC-Pva-102323	Pteropus vampyrus	54.48	0.00e+00	1179.00
IUUC-Ptt-103794	Puccinia triticina	30.43	9.70e-01	28.90
IUUC-Rno-105473	Rattus norvegicus	56.87	0.00e+00	2977.00
IUUC-Sha-106537	Sarcophilus harrisii	57.66	0.00e+00	3032.00
IUUC-Sly-111015	Solanum lycopersicum	27.68	4.00e-06	45.80
IUUC-Stu-112815	Solanum tuberosum	27.68	4.00e-06	45.80
IUUC-Sar-113031	Sorex araneus	60.54	0.00e+00	811.00
IUUC-Ssc-115622	Sus scrofa	54.80	0.00e+00	1379.00
IUUC-Tgu-116781	Taeniopygia guttata	51.44	0.00e+00	1831.00
IUUC-Tru-118684	Takifugu rubripes	43.04	0.00e+00	1021.00
IUUC-Tsy-119490	Tarsius syrichta	50.73	0.00e+00	1099.00
IUUC-Tbe-127349	Tupaia belangeri	58.07	0.00e+00	1104.00
IUUC-Ttr-128883	Tursiops truncatus	52.35	0.00e+00	919.00
IUUC-Vpa-130224	Vicugna pacos	53.45	0.00e+00	1536.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence