iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034360

Ensembl Protein ID

ENSECAP00000002021.1

UniProt Accession

F7DZG1; F7DZG1_HORSE

Protein Name

Uncharacterized protein

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000002490.1	ENSECAT00000002824.1	ENSECAP00000002021.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	3.00e-51	174.8	30	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqy++l+i+eg+ + i+cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+ +
   Q: 30   CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHgtLQEAEIAC-LVPVDQFQLYQRLKFEREVHLDPYR 118
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++++  + + vec++c+ +fC++Ck+ wH+++sC+e +  +  te   + a   + +ea +k+Cp C+vyie+neg
   Q: 119  TWCPVADCQTVCPVASSDpgQPVLVECPSCHLKFCSCCKDVWHAEVSCRESQPIVLPTE---HGALFGTDAEAPIKQCPVCRVYIERNEG 205
           *************9998877899999*****************************9999...89************************** PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 206  CAQMMCKNCKHTFCWYC 222
           ***************** PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MGSAGRLQYL TMTAENSTPG DLALAPLVTC KLCLCEQSLD KMTTLQECQC IFCTACLKQY 60
MQLAIREGCG SPITCPDMVC LNHGTLQEAE IACLVPVDQF QLYQRLKFER EVHLDPYRTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCGGTTA TAGGTACTCC TCCTCCTCCG ACCCGATAGG TCTGGGAGCC CAAATCCTGT 60
TGTAATCCCG CAGAGCGTAA AGCTGTCAGC CGCAGAGCTC GGAGGAAGAA GGAGAGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ecb:100052124

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	95.05	2.00e-171	594.00
IUUC-Apl-004112	Anas platyrhynchos	83.63	6.00e-133	466.00
IUUC-Aca-004533	Anolis carolinensis	78.22	4.00e-140	490.00
IUUC-Bta-012641	Bos taurus	94.41	2.00e-169	587.00
IUUC-Cja-019626	Callithrix jacchus	81.85	2.00e-143	501.00
IUUC-Cfa-020702	Canis familiaris	94.72	2.00e-171	593.00
IUUC-Cpo-022147	Cavia porcellus	95.05	3.00e-169	587.00
IUUC-Csa-023473	Chlorocebus sabaeus	95.71	1.00e-173	602.00
IUUC-Cho-024298	Choloepus hoffmanni	91.05	5.00e-141	493.00
IUUC-Dre-028099	Danio rerio	65.41	3.00e-92	331.00
IUUC-Dno-029122	Dasypus novemcinctus	88.82	1.00e-158	551.00
IUUC-Dor-030669	Dipodomys ordii	95.71	1.00e-133	468.00
IUUC-Ete-033141	Echinops telfairi	80.20	2.00e-131	461.00
IUUC-Eeu-034538	Erinaceus europaeus	73.24	1.00e-85	308.00
IUUC-Fca-036055	Felis catus	93.07	6.00e-168	582.00
IUUC-Fal-037339	Ficedula albicollis	82.44	1.00e-135	475.00
IUUC-Gmo-038780	Gadus morhua	61.76	6.00e-86	310.00
IUUC-Gga-040256	Gallus gallus	81.14	4.00e-135	473.00
IUUC-Gac-042127	Gasterosteus aculeatus	61.90	4.00e-93	334.00
IUUC-Ggo-044867	Gorilla gorilla	97.69	6.00e-176	609.00
IUUC-Hsa-046928	Homo sapiens	97.36	2.00e-175	607.00
IUUC-Hvu-047484	Hordeum vulgare	30.62	7.00e-18	85.10
IUUC-Itr-048250	Ictidomys tridecemlineatus	96.89	2.00e-110	390.00
IUUC-Lch-050168	Latimeria chalumnae	75.08	1.00e-134	471.00
IUUC-Lpe-051649	Leersia perrieri	29.06	1.00e-16	82.40
IUUC-Loc-052150	Lepisosteus oculatus	61.29	1.00e-88	319.00
IUUC-Laf-053967	Loxodonta africana	95.38	3.00e-172	597.00
IUUC-Mcc-055898	Macaca mulatta	95.71	1.00e-173	602.00
IUUC-Meu-056628	Macropus eugenii	97.44	2.00e-43	169.00
IUUC-Mtr-057989	Medicago truncatula	26.42	3.00e-18	85.50
IUUC-Mga-059820	Meleagris gallopavo	80.43	1.00e-133	468.00
IUUC-Mmr-060680	Microcebus murinus	94.06	2.00e-169	587.00
IUUC-Mdo-062839	Monodelphis domestica	86.18	9.00e-155	538.00
IUUC-Mmu-063339	Mus musculus	87.79	5.00e-148	516.00
IUUC-Mac-065414	Musa acuminata	28.44	4.00e-19	88.60
IUUC-Mpu-065973	Mustela putorius furo	93.07	7.00e-169	585.00
IUUC-Mlu-067112	Myotis lucifugus	95.38	1.00e-163	568.00
IUUC-Nle-069795	Nomascus leucogenys	97.03	1.00e-175	608.00
IUUC-Opr-070390	Ochotona princeps	88.45	2.00e-154	537.00
IUUC-Ont-072329	Oreochromis niloticus	61.27	2.00e-90	325.00
IUUC-Oan-072980	Ornithorhynchus anatinus	77.27	7.00e-138	483.00
IUUC-Ocu-073845	Oryctolagus cuniculus	95.38	7.00e-172	595.00
IUUC-Ola-086872	Oryzias latipes	62.17	7.00e-86	310.00
IUUC-Oga-088954	Otolemur garnettii	95.05	1.00e-171	595.00
IUUC-Oar-089879	Ovis aries	95.07	3.00e-170	590.00
IUUC-Ptr-090685	Pan troglodytes	97.36	2.00e-175	607.00
IUUC-Pan-092086	Papio anubis	95.38	1.00e-173	601.00
IUUC-Psi-093481	Pelodiscus sinensis	82.51	7.00e-141	492.00
IUUC-Pfo-096065	Poecilia formosa	65.91	1.00e-92	332.00
IUUC-Pab-098031	Pongo abelii	96.70	3.00e-174	603.00
IUUC-Pca-100936	Procavia capensis	91.75	3.00e-165	573.00
IUUC-Pva-102864	Pteropus vampyrus	85.81	2.00e-150	524.00
IUUC-Rno-105503	Rattus norvegicus	87.79	9.00e-148	515.00
IUUC-Sha-107425	Sarcophilus harrisii	86.84	5.00e-156	543.00
IUUC-Stu-112736	Solanum tuberosum	28.30	2.00e-18	86.30
IUUC-Ssc-115458	Sus scrofa	94.14	1.00e-159	555.00
IUUC-Tgu-117226	Taeniopygia guttata	81.36	3.00e-135	474.00
IUUC-Tru-118362	Takifugu rubripes	65.04	4.00e-94	337.00
IUUC-Tsy-119255	Tarsius syrichta	96.70	2.00e-174	604.00
IUUC-Tni-120140	Tetraodon nigroviridis	62.45	2.00e-89	321.00
IUUC-Tae-124420	Triticum aestivum	31.86	3.00e-18	86.70
IUUC-Tbe-127306	Tupaia belangeri	95.38	2.00e-171	594.00
IUUC-Ttr-128923	Tursiops truncatus	95.07	1.00e-158	551.00
IUUC-Vpa-130148	Vicugna pacos	95.38	2.00e-171	594.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence