iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sit-110340

Ensembl Protein ID

Si005833m

UniProt Accession

K3XV76; K3XV76_SETIT

Genbank Protein ID

KQL11565.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

CM003531

Gene Name

LOC101781081; SETIT_005833mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Si005833m.g	Si005833m	Si005833m
Si005833m.g	Si005837m	Si005837m

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-32	110.3	153	194
UBD/Beta-Prp	9.30e-63	213.1	2	260

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 153  GHSKGVNCVDYftgGDrPYLITGSDDQTAKVWDYQTKSCVQT 194
           8********966*9778*******************999986 PP

UBD/Beta-Prp

   S: 27   tgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletg 126
           ++ ++g++ +w+++t+++++s++  e +v++ kf+p++++ v g++D++i+v++++t + v  +++h+d++++++++p+  +++s s+d  i++wd+++g
   Q: 2    SSLYSGSVCIWNYQTQTMVKSFEVSELPVRSAKFIPRKQWVVAGADDMFIRVYNYNTMDKVKMFEAHTDYIRCVAVHPTLPYVLSSSDDMLIKLWDWDKG 101
           577899********************************************************************************************** PP
   S: 127  qcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
           ++  ++++gh++ v+ v+++p++ n ++s+slDrtv++W+l + +   tl g h + v++++     ++++l++gs+d+t k+wd+qt++cv+tl+gh  
   Q: 102  WVCTQIFEGHSHYVMQVTFNPKDtNTFASASLDRTVKIWSLGSPDPNFTLDG-HSKGVNCVDyfTGGDRPYLITGSDDQTAKVWDYQTKSCVQTLEGHAH 200
           *9999**********************************************9.*********7445566******************************* PP
   S: 224  nvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlg 283
           nv+ v f+p+  ++++gs+Dg++r+W +++  l +tl++  ++v++  +++ +++v++  
   Q: 201  NVSAVCFHPEVPIIMTGSEDGTVRLWHSTTYRLENTLNYGLERVWALGCMKGSRRVVIGY 260
           *************************************************77777766433 PP

Organism

Setaria italica

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MSSLYSGSVC IWNYQTQTMV KSFEVSELPV RSAKFIPRKQ WVVAGADDMF IRVYNYNTMD 60
KVKMFEAHTD YIRCVAVHPT LPYVLSSSDD MLIKLWDWDK GWVCTQIFEG HSHYVMQVTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAAGCTCG CGCAGAGGTC GGAGAGGGTC AAGTCCGTGG ACTTGCATCC CACCGAACCA 60
TGGTAAGTGT GCTACTGTTT GTTGTCTTAG TTGTATGCTG CTAGGTTAAT GTATCGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008535	Aspergillus flavus	50.36	0.00e+00	860.00
IUUC-Bta-013579	Bos taurus	62.46	0.00e+00	976.00
IUUC-Eeu-035086	Erinaceus europaeus	48.09	1.00e-124	440.00
IUUC-Fal-037202	Ficedula albicollis	59.24	0.00e+00	1071.00
IUUC-Meu-056174	Macropus eugenii	52.66	5.00e-110	391.00
IUUC-Oan-073416	Ornithorhynchus anatinus	60.61	0.00e+00	1057.00
IUUC-Opu-083125	Oryza punctata	92.07	0.00e+00	1606.00
IUUC-Stu-112906	Solanum tuberosum	81.90	0.00e+00	1414.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence