iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037625

Ensembl Protein ID

ENSFALP00000007982.1

UniProt Accession

U3JYX8; U3JYX8_FICAL

Genbank Protein ID

ENSFALP00000007982

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010899

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000007648.1	ENSFALT00000008015.1	ENSFALP00000007982.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.30e-82	276.1	446	901

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCYmNS++Q+L++ +++r+ +l+     l e    +++++l+++lq lf+ l +s++ a+sp+++l+a +   + f+  +qq
   Q: 446  GLINLGNTCYMNSIIQSLFMASDFRHSVLN-----LTE----GNSQPLMTKLQWLFAFLEHSQRPAISPESFLSASW--PPWFTPGAQQ 523
           9*****************************.....432....45689***************************987..788******* PP
   S: 91   DaqEflaflld..qleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           D++E+l++lld  +l+ee      k+ ++  ++ k+++ +++  +++  nk+li+++F+g++ ++i+cl+c nvssree f+dlsl++p
   Q: 524  DCSEYLKYLLDsqRLHEEE-----KTGKRIYQKLKESSLMSQAVEHHYLNKTLIEKMFGGKMMTKIRCLKCLNVSSREEAFTDLSLAFP 607
           **********933477777.....3333444444444556667899******************************************* PP
   S: 178  gkeetkke................................................................................. 185
            ++ +                                                                                    
   Q: 608  PSDRNV-Hgstsiqpveeigpqfieppenagqltgspwiqrkapmasdhaapsvlvetlgfqepgeaanpirgndvgvdaakdplstfr 695
           998654.35899***************************************************************************** PP
   S: 186  ..........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
                     s+ d+++ f ++e+l+ enky+cekc ++q+aek  +l++ P++Lil L Rfsf+ ++++r+ki ++v++p  L+l  +
   Q: 696  eqecaskdsrSVPDLINYFLSPERLTAENKYHCEKCASLQDAEKVAELTEGPHYLILTLLRFSFDPRTMKRKKILDNVSIPVVLKLP-V 783
           **************************************************************************************7.6 PP
   S: 265  ctspeekqke...............kkkYeLiavvvHsG.slssGHYvayvkn........................ekgkWllfdDsk 313
           ++ pee++++               ++ Y+L++vvvHsG s++sGHY++y ++                         + +W+lf+D++
   Q: 784  LVAPEETEEVcccgkdgavpgrgfmTVVYDLCSVVVHSGiSSESGHYYCYSREctdtlphgqpqggvpkqasdkqldFEIQWYLFNDTR 872
           66666666668**************************************************99999999987766555666******** PP
   S: 314  Vtevkeeevleetg....staYvlfYkrr 338
           V+ ++ e+v + t+    +taYvlfY++r
   Q: 873  VSFSSFESVSNVTSffpkDTAYVLFYRQR 901
           ***********999************985 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MDKILEAVVM SSYPNNVKQG LVRRVLEAAK QPMDSEQCWS MLELSTKLYL TGDTKYKREI 60
GKEVLEVYGH YHPEEFEEFF NVRFLLSLLQ EGYGPLGKRS HYVLDYIQLG LQFVLESPSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGCAGTG ATGTGAAGAG GTGAAGTGGG AAGGCTTCCT AACCAAGCAG CTGTGAGTCA 60
GAGCTTGATG TTTGTGTCTG GCAGGGTTTT ACTTCTCCAC CTTCAAGCAA CTGTCTGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004121	Anas platyrhynchos	90.80	0.00e+00	1681.00
IUUC-Aca-005070	Anolis carolinensis	69.74	0.00e+00	921.00
IUUC-Bta-012545	Bos taurus	68.97	0.00e+00	888.00
IUUC-Cja-019731	Callithrix jacchus	67.70	0.00e+00	876.00
IUUC-Cfa-020095	Canis familiaris	68.44	0.00e+00	902.00
IUUC-Cpo-021961	Cavia porcellus	64.40	0.00e+00	1009.00
IUUC-Csa-023167	Chlorocebus sabaeus	69.59	0.00e+00	874.00
IUUC-Cin-025604	Ciona intestinalis	28.96	2.00e-45	176.00
IUUC-Dor-030538	Dipodomys ordii	72.10	0.00e+00	768.00
IUUC-Dme-031871	Drosophila melanogaster	32.69	3.00e-45	176.00
IUUC-Eeu-035120	Erinaceus europaeus	52.30	0.00e+00	638.00
IUUC-Gga-040767	Gallus gallus	89.97	0.00e+00	1747.00
IUUC-Hsa-046124	Homo sapiens	69.75	0.00e+00	882.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	64.05	0.00e+00	1117.00
IUUC-Lch-049513	Latimeria chalumnae	62.72	0.00e+00	1152.00
IUUC-Loc-052698	Lepisosteus oculatus	59.01	0.00e+00	1082.00
IUUC-Laf-053999	Loxodonta africana	64.43	0.00e+00	1132.00
IUUC-Mcc-055266	Macaca mulatta	68.59	0.00e+00	856.00
IUUC-Meu-056906	Macropus eugenii	75.85	0.00e+00	1038.00
IUUC-Mga-059595	Meleagris gallopavo	87.68	0.00e+00	1690.00
IUUC-Mdo-062167	Monodelphis domestica	71.87	0.00e+00	1347.00
IUUC-Mmu-063298	Mus musculus	70.86	0.00e+00	885.00
IUUC-Mpu-066195	Mustela putorius furo	68.54	0.00e+00	889.00
IUUC-Mlu-067583	Myotis lucifugus	66.21	0.00e+00	649.00
IUUC-Opr-070454	Ochotona princeps	62.86	1.00e-113	404.00
IUUC-Ocu-074121	Oryctolagus cuniculus	59.67	0.00e+00	966.00
IUUC-Oga-088593	Otolemur garnettii	64.10	0.00e+00	1086.00
IUUC-Oar-090140	Ovis aries	67.32	0.00e+00	880.00
IUUC-Pan-092168	Papio anubis	69.75	0.00e+00	875.00
IUUC-Psi-093707	Pelodiscus sinensis	83.38	0.00e+00	1587.00
IUUC-Pab-097614	Pongo abelii	69.59	0.00e+00	880.00
IUUC-Pca-100683	Procavia capensis	65.04	0.00e+00	849.00
IUUC-Rno-105061	Rattus norvegicus	70.21	0.00e+00	884.00
IUUC-Sha-106686	Sarcophilus harrisii	74.89	0.00e+00	1023.00
IUUC-Tgu-117024	Taeniopygia guttata	94.40	0.00e+00	1816.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence