iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004801

UUCD1 version

UUC-AnC-00853

Ensembl Protein ID

ENSACAP00000016815.2

UniProt Accession

G1KTI4; G1KTI4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000017093.2	ENSACAT00000017147.2	ENSACAP00000016815.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.50e-14	52.0	67	141
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.10e-09	37.5	175	205

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg...geeffahkivLaasSsvFyalflmeleesksklmveikd......vqpevfrallkFlYtgklde 67
           +Dv+l  g    +ef+ah++vLaa+ ++F  l+++++ es+ +++ve++        +pe ++a+++F+Ytg+++ 
   Q: 67   CDVTLSFGggaPREFRAHRSVLAAATEYFAPLLSGDFAESR-SGRVELRKwsseagPDPETVEAVISFMYTGRVRV 141
           8******876779****************************.*******4456799*****************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           l+N ++i ++A++y++ +L+++a d+i ++F
   Q: 175  LSNSVAIHSLAHMYSLNQLALKAADMIRRNF 205
           69****************************9 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

RTKMAAAGGG GDLDGGGQGA PESGVALGAE GEAGAEAEPD SEVFSCVAHC SELACRQNEQ 60
RRLGLFCDVT LSFGGGAPRE FRAHRSVLAA ATEYFAPLLS GDFAESRSGR VELRKWSSEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAACCAAGA TGGCGGCGGC TGGAGGCGGA GGCGACTTAG ACGGCGGGGG GCAAGGCGCT 60
CCGGAGAGTG GCGTCGCCCT GGGCGCGGAA GGCGAGGCCG GGGCGGAGGC GGAGCCCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002239	Ailuropoda melanoleuca	79.36	0.00e+00	1105.00
IUUC-Apl-003928	Anas platyrhynchos	85.29	0.00e+00	1046.00
IUUC-Aly-006525	Arabidopsis lyrata	27.73	4.00e-13	69.30
IUUC-Ame-010943	Astyanax mexicanus	76.71	0.00e+00	908.00
IUUC-Bta-012341	Bos taurus	85.71	3.00e-84	303.00
IUUC-Cja-019924	Callithrix jacchus	81.65	0.00e+00	1130.00
IUUC-Cfa-021076	Canis familiaris	81.96	0.00e+00	1136.00
IUUC-Cpo-022193	Cavia porcellus	80.97	0.00e+00	1103.00
IUUC-Csa-023614	Chlorocebus sabaeus	81.65	0.00e+00	1130.00
IUUC-Cho-024806	Choloepus hoffmanni	67.74	0.00e+00	729.00
IUUC-Dre-028622	Danio rerio	75.62	0.00e+00	993.00
IUUC-Dno-029965	Dasypus novemcinctus	79.29	0.00e+00	1090.00
IUUC-Dor-030136	Dipodomys ordii	82.89	0.00e+00	943.00
IUUC-Eca-034191	Equus caballus	81.80	0.00e+00	1130.00
IUUC-Eeu-034746	Erinaceus europaeus	81.49	0.00e+00	1127.00
IUUC-Fca-035702	Felis catus	74.66	0.00e+00	1020.00
IUUC-Fal-037360	Ficedula albicollis	84.17	0.00e+00	1031.00
IUUC-Gmo-038582	Gadus morhua	74.73	0.00e+00	986.00
IUUC-Gga-040375	Gallus gallus	84.16	0.00e+00	1130.00
IUUC-Gac-042523	Gasterosteus aculeatus	76.00	0.00e+00	980.00
IUUC-Ggo-045632	Gorilla gorilla	82.77	0.00e+00	943.00
IUUC-Hsa-046817	Homo sapiens	81.65	0.00e+00	1131.00
IUUC-Itr-048433	Ictidomys tridecemlineatus	81.96	0.00e+00	1136.00
IUUC-Lch-049985	Latimeria chalumnae	79.34	0.00e+00	1034.00
IUUC-Loc-052594	Lepisosteus oculatus	75.19	0.00e+00	981.00
IUUC-Laf-054357	Loxodonta africana	81.96	0.00e+00	1137.00
IUUC-Mcc-055454	Macaca mulatta	81.65	0.00e+00	1130.00
IUUC-Meu-056012	Macropus eugenii	82.06	4.00e-146	510.00
IUUC-Mga-060048	Meleagris gallopavo	85.34	0.00e+00	866.00
IUUC-Mdo-062082	Monodelphis domestica	83.98	0.00e+00	1165.00
IUUC-Mmu-063119	Mus musculus	82.12	0.00e+00	1143.00
IUUC-Mpu-066511	Mustela putorius furo	81.80	0.00e+00	1135.00
IUUC-Mlu-067301	Myotis lucifugus	82.08	0.00e+00	1125.00
IUUC-Nle-069912	Nomascus leucogenys	81.65	0.00e+00	1131.00
IUUC-Opr-070762	Ochotona princeps	80.99	0.00e+00	720.00
IUUC-Ont-071916	Oreochromis niloticus	76.59	0.00e+00	990.00
IUUC-Oan-072932	Ornithorhynchus anatinus	75.52	0.00e+00	804.00
IUUC-Ocu-074172	Oryctolagus cuniculus	83.27	0.00e+00	936.00
IUUC-Ola-086483	Oryzias latipes	75.81	0.00e+00	981.00
IUUC-Oga-088112	Otolemur garnettii	80.96	0.00e+00	1095.00
IUUC-Oar-090129	Ovis aries	81.80	0.00e+00	1134.00
IUUC-Ptr-090571	Pan troglodytes	82.70	0.00e+00	941.00
IUUC-Pan-092073	Papio anubis	81.80	0.00e+00	1132.00
IUUC-Psi-093836	Pelodiscus sinensis	84.72	0.00e+00	1070.00
IUUC-Pfo-096477	Poecilia formosa	76.12	0.00e+00	986.00
IUUC-Pab-098473	Pongo abelii	81.65	0.00e+00	1131.00
IUUC-Pca-100239	Procavia capensis	81.15	0.00e+00	647.00
IUUC-Rno-104859	Rattus norvegicus	82.12	0.00e+00	1140.00
IUUC-Sha-106746	Sarcophilus harrisii	84.40	0.00e+00	1164.00
IUUC-Sre-115185	Sporisorium reilianum	33.82	2.00e-04	38.90
IUUC-Tgu-117183	Taeniopygia guttata	83.64	0.00e+00	1130.00
IUUC-Tru-118655	Takifugu rubripes	74.54	0.00e+00	965.00
IUUC-Tsy-119430	Tarsius syrichta	82.13	0.00e+00	1128.00
IUUC-Tni-119698	Tetraodon nigroviridis	74.96	0.00e+00	857.00
IUUC-Vpa-130715	Vicugna pacos	81.34	0.00e+00	1117.00
IUUC-Xtr-132276	Xenopus tropicalis	76.64	0.00e+00	987.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence