iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028622

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 11

Genbank Nucleotide ID

CR847824

Gene Name

klhl11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000045130.4	ENSDART00000066368.3	ENSDARP00000066367.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.10e-10	41.7	101	164
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.00e-10	40.7	199	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 9    geeffahkivLaasSsvFyalflmeleesksklmveikd......vqpevfrallkFlYtgklde 67
           + ef+ah++vLaa+ ++F  l+ ++++es  + +ve+k+      ++ e ++ +++F+Ytg+++ 
   Q: 101  NFEFNAHRSVLAAATDYFTPLLGGQFSESV-TRRVEMKEwsseagLDQETVESVIQFMYTGEIRV 164
           679**************************8.*******6667899****************9975 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Nc++i ++A++y++++L+++a d+i ++F+
   Q: 199  GNCVAIHSLAHMYTLDQLALRAADMIRRNFH 229
           5*****************************8 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MLECVCLSVL HHLNILRTLR TESADTEMAA AAPNPEDASR NSSSPSTPSA LMGDGESEEA 60
EEFASATHCS ELSRRQNEQR KLGLFCDVTL AFSSAPGAAN NFEFNAHRSV LAAATDYFTP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTGCGCAT GTGCGTGTTG TTCAGCTCTG TTTATGTTGG AGTGTGTGTG TTTGAGTGTG 60
CTCCACCACC TCAACATACT GCGCACTTTA CGAACCGAGA GCGCGGACAC CGAGATGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002239	Ailuropoda melanoleuca	74.22	0.00e+00	991.00
IUUC-Apl-003928	Anas platyrhynchos	75.26	0.00e+00	915.00
IUUC-Aca-004801	Anolis carolinensis	75.62	0.00e+00	979.00
IUUC-Ame-010943	Astyanax mexicanus	96.85	0.00e+00	1115.00
IUUC-Bta-012341	Bos taurus	79.76	3.00e-79	286.00
IUUC-Cja-019924	Callithrix jacchus	75.00	0.00e+00	1012.00
IUUC-Cfa-021076	Canis familiaris	75.16	0.00e+00	1016.00
IUUC-Cpo-022193	Cavia porcellus	74.53	0.00e+00	993.00
IUUC-Csa-023614	Chlorocebus sabaeus	75.00	0.00e+00	1011.00
IUUC-Cho-024806	Choloepus hoffmanni	71.84	2.00e-151	529.00
IUUC-Dno-029965	Dasypus novemcinctus	72.67	0.00e+00	969.00
IUUC-Dor-030136	Dipodomys ordii	75.76	0.00e+00	853.00
IUUC-Eca-034191	Equus caballus	74.84	0.00e+00	1009.00
IUUC-Eeu-034746	Erinaceus europaeus	74.53	0.00e+00	1003.00
IUUC-Fca-035702	Felis catus	70.20	0.00e+00	917.00
IUUC-Fal-037360	Ficedula albicollis	77.74	0.00e+00	940.00
IUUC-Gmo-038582	Gadus morhua	89.43	0.00e+00	1182.00
IUUC-Gga-040375	Gallus gallus	74.77	0.00e+00	1006.00
IUUC-Gac-042523	Gasterosteus aculeatus	87.76	0.00e+00	1154.00
IUUC-Ggo-045632	Gorilla gorilla	76.04	0.00e+00	859.00
IUUC-Hsa-046817	Homo sapiens	75.00	0.00e+00	1012.00
IUUC-Itr-048433	Ictidomys tridecemlineatus	74.84	0.00e+00	1010.00
IUUC-Lch-049985	Latimeria chalumnae	82.47	0.00e+00	1066.00
IUUC-Loc-052594	Lepisosteus oculatus	85.92	0.00e+00	1132.00
IUUC-Laf-054357	Loxodonta africana	75.16	0.00e+00	1015.00
IUUC-Mcc-055454	Macaca mulatta	75.00	0.00e+00	1011.00
IUUC-Meu-056012	Macropus eugenii	72.91	1.00e-127	449.00
IUUC-Mga-060048	Meleagris gallopavo	76.27	0.00e+00	777.00
IUUC-Mdo-062082	Monodelphis domestica	76.41	0.00e+00	1038.00
IUUC-Mmu-063119	Mus musculus	75.16	0.00e+00	1013.00
IUUC-Mpu-066511	Mustela putorius furo	75.00	0.00e+00	1015.00
IUUC-Mlu-067301	Myotis lucifugus	75.31	0.00e+00	1015.00
IUUC-Nle-069912	Nomascus leucogenys	75.00	0.00e+00	1012.00
IUUC-Opr-070762	Ochotona princeps	73.96	0.00e+00	637.00
IUUC-Ont-071916	Oreochromis niloticus	86.95	0.00e+00	1164.00
IUUC-Oan-072932	Ornithorhynchus anatinus	70.32	0.00e+00	743.00
IUUC-Ocu-074172	Oryctolagus cuniculus	76.25	0.00e+00	850.00
IUUC-Ola-086483	Oryzias latipes	87.14	0.00e+00	1147.00
IUUC-Oga-088112	Otolemur garnettii	74.65	0.00e+00	979.00
IUUC-Oar-090129	Ovis aries	75.16	0.00e+00	1013.00
IUUC-Ptr-090571	Pan troglodytes	75.95	0.00e+00	855.00
IUUC-Pan-092073	Papio anubis	75.00	0.00e+00	1012.00
IUUC-Psi-093836	Pelodiscus sinensis	74.11	0.00e+00	933.00
IUUC-Pfo-096477	Poecilia formosa	88.70	0.00e+00	1165.00
IUUC-Pab-098473	Pongo abelii	75.00	0.00e+00	1012.00
IUUC-Pca-100239	Procavia capensis	74.34	3.00e-167	582.00
IUUC-Rno-104859	Rattus norvegicus	75.31	0.00e+00	1013.00
IUUC-Sha-106746	Sarcophilus harrisii	76.56	0.00e+00	1040.00
IUUC-Tgu-117183	Taeniopygia guttata	75.04	0.00e+00	1006.00
IUUC-Tru-118655	Takifugu rubripes	86.94	0.00e+00	1160.00
IUUC-Tsy-119430	Tarsius syrichta	75.16	0.00e+00	1014.00
IUUC-Tni-119698	Tetraodon nigroviridis	86.58	0.00e+00	1026.00
IUUC-Vpa-130715	Vicugna pacos	74.69	0.00e+00	1000.00
IUUC-Xtr-132276	Xenopus tropicalis	73.28	0.00e+00	910.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence