iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036431

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02019605

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000008956.3	ENSFCAT00000008958.3	ENSFCAP00000008302.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-25	86.9	368	400
UBD/Beta-Prp	5.80e-45	153.8	281	489

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrt 32
           gHtd vt+  f  ++ +vsGsdD t+kvWDlr 
   Q: 368  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLRN 400
           8*******99*733669*************986 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 281  KSHQGVVIAADWLVGGKQAVTASWDRTANLFDVETAELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 369
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 370  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLRNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 456
           ******99999.********************998874555555.55555555559*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 457  RRMVCCSAWSEDHpmCNLFTCGFDRQAIGWNIN 489
           *********9999777899***********986 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MPTESGSCST ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQQDSK LPSSVRSTLL 60
ELFGQIEREF ENLYIENLEL RREIETLNER LAAEGQAIDG AELSKGQLKT KASHSTSQLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCACAG AAAGCGGGAG TTGCTCCACT GCTCGCCAAG CAAAACAGAA ACGCAAATCT 60
CATAGCCTTT CTATACGAAG AACGAACAGC TCGGAGCAGG AGAGGACGGG TCTGCCAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	98.79	0.00e+00	979.00
IUUC-Apl-003647	Anas platyrhynchos	92.35	0.00e+00	926.00
IUUC-Aca-004759	Anolis carolinensis	92.15	0.00e+00	938.00
IUUC-Ame-011103	Astyanax mexicanus	55.84	3.00e-142	498.00
IUUC-Bta-012718	Bos taurus	95.77	0.00e+00	958.00
IUUC-Cel-018499	Caenorhabditis elegans	42.26	5.00e-96	344.00
IUUC-Cja-019492	Callithrix jacchus	96.18	0.00e+00	987.00
IUUC-Cfa-020199	Canis familiaris	98.59	0.00e+00	1011.00
IUUC-Cpo-022500	Cavia porcellus	90.54	0.00e+00	936.00
IUUC-Csa-023567	Chlorocebus sabaeus	96.78	0.00e+00	993.00
IUUC-Cho-025071	Choloepus hoffmanni	68.21	0.00e+00	639.00
IUUC-Cin-025460	Ciona intestinalis	44.75	9.00e-104	370.00
IUUC-Csv-026042	Ciona savignyi	45.76	2.00e-108	385.00
IUUC-Dre-028214	Danio rerio	81.69	0.00e+00	852.00
IUUC-Dno-029826	Dasypus novemcinctus	94.70	0.00e+00	820.00
IUUC-Dor-030967	Dipodomys ordii	95.81	0.00e+00	889.00
IUUC-Dme-031936	Drosophila melanogaster	49.79	2.00e-119	422.00
IUUC-Ete-032452	Echinops telfairi	92.35	0.00e+00	943.00
IUUC-Eca-033278	Equus caballus	97.18	0.00e+00	1001.00
IUUC-Eeu-034592	Erinaceus europaeus	83.90	0.00e+00	831.00
IUUC-Fal-037149	Ficedula albicollis	91.55	0.00e+00	921.00
IUUC-Gmo-038476	Gadus morhua	77.25	0.00e+00	761.00
IUUC-Gga-041099	Gallus gallus	92.35	0.00e+00	927.00
IUUC-Gac-042374	Gasterosteus aculeatus	85.00	0.00e+00	832.00
IUUC-Ggo-044683	Gorilla gorilla	88.53	0.00e+00	898.00
IUUC-Hsa-046658	Homo sapiens	95.98	0.00e+00	986.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	96.71	0.00e+00	920.00
IUUC-Lch-050571	Latimeria chalumnae	83.52	0.00e+00	867.00
IUUC-Loc-052652	Lepisosteus oculatus	81.33	0.00e+00	853.00
IUUC-Laf-053712	Loxodonta africana	95.20	0.00e+00	976.00
IUUC-Mcc-055521	Macaca mulatta	96.78	0.00e+00	993.00
IUUC-Meu-056324	Macropus eugenii	88.93	0.00e+00	882.00
IUUC-Mga-060114	Meleagris gallopavo	92.56	0.00e+00	933.00
IUUC-Mmr-061176	Microcebus murinus	96.18	0.00e+00	986.00
IUUC-Mdo-061888	Monodelphis domestica	93.56	0.00e+00	921.00
IUUC-Mmu-063977	Mus musculus	95.98	0.00e+00	995.00
IUUC-Mpu-066220	Mustela putorius furo	86.13	0.00e+00	645.00
IUUC-Mlu-068155	Myotis lucifugus	97.38	0.00e+00	1003.00
IUUC-Nle-069964	Nomascus leucogenys	96.18	0.00e+00	989.00
IUUC-Opr-070925	Ochotona princeps	94.20	5.00e-150	523.00
IUUC-Ont-071317	Oreochromis niloticus	85.92	0.00e+00	841.00
IUUC-Oan-072952	Ornithorhynchus anatinus	93.96	0.00e+00	949.00
IUUC-Ocu-073913	Oryctolagus cuniculus	96.58	0.00e+00	999.00
IUUC-Ola-087024	Oryzias latipes	84.34	0.00e+00	877.00
IUUC-Oga-087945	Otolemur garnettii	95.77	0.00e+00	992.00
IUUC-Oar-089854	Ovis aries	95.98	0.00e+00	948.00
IUUC-Ptr-091486	Pan troglodytes	96.18	0.00e+00	988.00
IUUC-Pan-091738	Papio anubis	96.78	0.00e+00	993.00
IUUC-Psi-093953	Pelodiscus sinensis	91.95	0.00e+00	928.00
IUUC-Pma-094560	Petromyzon marinus	74.74	0.00e+00	760.00
IUUC-Pfo-097222	Poecilia formosa	84.51	0.00e+00	827.00
IUUC-Pab-098778	Pongo abelii	91.15	0.00e+00	924.00
IUUC-Pca-100852	Procavia capensis	91.95	0.00e+00	924.00
IUUC-Pva-103130	Pteropus vampyrus	96.71	3.00e-135	475.00
IUUC-Rno-105848	Rattus norvegicus	86.92	0.00e+00	878.00
IUUC-Sha-106750	Sarcophilus harrisii	93.76	0.00e+00	951.00
IUUC-Sar-113749	Sorex araneus	87.32	0.00e+00	879.00
IUUC-Ssc-115691	Sus scrofa	94.37	0.00e+00	937.00
IUUC-Tgu-117365	Taeniopygia guttata	90.95	0.00e+00	877.00
IUUC-Tru-117595	Takifugu rubripes	83.30	0.00e+00	826.00
IUUC-Tsy-118973	Tarsius syrichta	75.27	1.00e-152	532.00
IUUC-Tni-120545	Tetraodon nigroviridis	83.17	0.00e+00	862.00
IUUC-Tbe-127976	Tupaia belangeri	71.43	0.00e+00	688.00
IUUC-Ttr-128472	Tursiops truncatus	93.36	0.00e+00	951.00
IUUC-Xtr-132621	Xenopus tropicalis	90.14	0.00e+00	892.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence