iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054461

UUCD1 version

UUC-LoA-00981

Ensembl Protein ID

ENSLAFP00000004945.4

UniProt Accession

G3SX40; G3SX40_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005899.4	ENSLAFT00000005896.4	ENSLAFP00000004945.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.00e-51	173.7	1	132
UBD/UBC-like/UBD_UBC	1.90e-80	268.1	1	136

Active Site

Position(s)	Description	Evidence
79	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 5    elkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPk..vkfltkifhPnvyenGkvClsilkeeek 91
           el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPk  v f+t+i+hPn+++nG++Cl+il+  ++
   Q: 1    ELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKanVAFTTRIYHPNINSNGSICLDILR--SQ 86
           7899****************.9************************************8557899*******************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           Wspal++++vllsi+sll++pnp++pl  e+a+++k++r +y+++ 
   Q: 87   WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRIS 132
           ******************************************9876 PP

UBD/UBC-like/UBD_UBC

   S: 5    elkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppk..vafitkiyhpninsngsicldilrsqwsa 91
           el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppk  vaf+t+iyhpninsngsicldilrsqws+
   Q: 1    ELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKanVAFTTRIYHPNINSNGSICLDILRSQWSP 89
           89*******************************************************97789*************************** PP
   S: 92   altlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           alt+skvlls+csll+d++pddplv+eiariyktd++ky+ri+rewt
   Q: 90   ALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWT 136
           **********************************************8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

ELSDLARDPP AQCSAGPVGD DMFHWQATIM GPNDSPYQGG VFFLTIHFPT DYPFKPPKAN 60
VAFTTRIYHP NINSNGSICL DILRSQWSPA LTISKVLLSI CSLLCDPNPD DPLVPEIARI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACTTAGTG ATTTGGCCCG TGACCCTCCA GCACAATGTT CTGCAGGTCC AGTTGGGGAT 60
GATAGTAAGT AACTTTCAAG TTGATTTTTA TGGCTGATTT CAAAAGAGCT TATGTATTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-018990	Callithrix jacchus	99.29	2.00e-81	293.00
IUUC-Eeu-034766	Erinaceus europaeus	97.16	5.00e-79	285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence