iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000011201.3	ENSMMUT00000015671.3	ENSMMUP00000014679.3
ENSMMUG00000011201.3	ENSMMUT00000015669.3	ENSMMUP00000014677.3
ENSMMUG00000011201.3	ENSMMUT00000015674.3	ENSMMUP00000014682.3
ENSMMUG00000011201.3	ENSMMUT00000058360.1	ENSMMUP00000059833.1
ENSMMUG00000011201.3	ENSMMUT00000077562.1	ENSMMUP00000052729.1
ENSMMUG00000011201.3	ENSMMUT00000015672.3	ENSMMUP00000014680.3
ENSMMUG00000011201.3	ENSMMUT00000065680.1	ENSMMUP00000050124.1
ENSMMUG00000011201.3	ENSMMUT00000056554.1	ENSMMUP00000058087.1
ENSMMUG00000011201.3	ENSMMUT00000059730.1	ENSMMUP00000052391.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.10e-54	183.2	11	141
UBD/UBC-like/UBD_UBC	7.60e-83	276.6	9	144

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 5    elkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWs 93
           el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++Ws
   Q: 11   ELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQWS 96
           999*****************.9************************************************************9..**** PP
   S: 94   palsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           pal++++vllsi+sll++pnp++pl  e+a+++k++r +y++ +r
   Q: 97   PALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRLAR 141
           *****************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 3    kkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsa 91
           k el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+
   Q: 9    KLELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSP 97
           3489************************************************************************************* PP
   S: 92   altlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           alt+skvlls+csll+d++pddplv+eiariyktd++ky+r arewt
   Q: 98   ALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRLAREWT 144
           **********************************************8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

PSLLKIQKKL ELSDLARDPP AQCSAGPVGD DMFHWQATIM GPNDSPYQGG VFFLTIHFPT 60
DYPFKPPKVA FTTRIYHPNI NSNGSICLDI LRSQWSPALT ISKVLLSICS LLCDPNPDDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCAAGTGAG GAAACTGGGG GACGCTGTGG GGAGGGGCGT GGGGCTGGAT CGCGCAGCGG 60
CAGCTTCCTT TACCTTCCTC CCATGGTCTC CTTCCGGTTC TCGATGCTTC TCTGAGCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004043	Anas platyrhynchos	100.00	8.00e-82	295.00
IUUC-Ang-009725	Aspergillus niger	84.80	6.00e-62	229.00
IUUC-Dor-030285	Dipodomys ordii	97.84	5.00e-80	288.00
IUUC-Eeu-034766	Erinaceus europaeus	99.29	4.00e-80	289.00
IUUC-Fal-036904	Ficedula albicollis	97.84	5.00e-80	289.00
IUUC-Gmo-038835	Gadus morhua	96.43	4.00e-79	286.00
IUUC-Gga-041015	Gallus gallus	95.97	7.00e-82	295.00
IUUC-Meu-056462	Macropus eugenii	96.40	8.00e-79	285.00
IUUC-Mga-059237	Meleagris gallopavo	97.84	6.00e-80	289.00
IUUC-Mmr-060889	Microcebus murinus	95.97	7.00e-82	295.00
IUUC-Mmu-063796	Mus musculus	95.97	7.00e-82	295.00
IUUC-Opr-070191	Ochotona princeps	97.84	5.00e-80	288.00
IUUC-Oga-088477	Otolemur garnettii	100.00	8.00e-82	295.00
IUUC-Pma-094405	Petromyzon marinus	96.97	2.00e-74	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence