iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107396

Ensembl Protein ID

ENSSHAP00000000189.1

UniProt Accession

G3VAI5; G3VAI5_SARHA

Genbank Protein ID

ENSSHAP00000000189

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01041205

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000000158.1	ENSSHAT00000000192.1	ENSSHAP00000000189.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.00e-53	177.8	1089	1141

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  +  d++W++g  e+ g +GlfP+n+v+ 
   Q: 1089 QVIAMYDYVANNEDELNFSKGQLINVL--NRDDADWWQG--ETGGVSGLFPANYVKM 1141
           6899***********************..889*******..9*************85 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

SHGGPSPCVP GGPNVWAITS EERTKHDKQF DSLRPAGGHI TGDQARGFFL QSGLPAPVLA 60
EIWTLSDLNK DGKMDQQEFS IAMKLIKLTL QGQRLPAALP PVMKQPPVLS PLASARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCATGGGG GCCCTTCCCC TTGTGTTCCA GGAGGCCCCA ACGTGTGGGC CATCACCTCG 60
GAGGAGCGGA CCAAGCACGA CAAGCAGTTC GACAGCCTCC GGCCCGCTGG GGGACACATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50002--SH3

Pfam

PF12763--EF-hand_4
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00054--EFh
SM00027--EH
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-019259	Callithrix jacchus	60.80	0.00e+00	806.00
IUUC-Eeu-034972	Erinaceus europaeus	67.11	4.00e-146	513.00
IUUC-Gac-041927	Gasterosteus aculeatus	45.62	0.00e+00	803.00
IUUC-Itr-048978	Ictidomys tridecemlineatus	63.28	0.00e+00	707.00
IUUC-Kpa-049215	Komagataella pastoris	37.14	5.00e-16	79.00
IUUC-Laf-053798	Loxodonta africana	64.45	0.00e+00	943.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence