iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020799

Ensembl Protein ID

ENSCAFP00000024833.4

UniProt Accession

E2RTI3; E2RTI3_CANLF

Genbank Protein ID

ENSCAFP00000024833

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03026415

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000016509.4	ENSCAFT00000026728.4	ENSCAFP00000024833.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	2.10e-10	40.7	581	618
ULD/UDP/UBQ/UBQ_PIM	2.40e-23	82.2	33	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 581  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 618
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 33   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQN 106
           69**********.***********************************************************986 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAENGESSGP PRPSRGPAAA QGPASAPAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA 60
ISKRFKSQTD QLVLIFAGKI LKDQDTLIQH GIHDGLTVHL VIKSQNRPQG QSTQPSNAAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ACGGCGAGAG TAGCGGCCCC CCGCGCCCCT CCCGCGGCCC TGCCGCGGCC 60
CAAGGCCCTG CCTCTGCCCC GGCCGAGCCC AAAATCATCA AAGTTACTGT GAAGACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

cfa:491909

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afu-009029	Aspergillus fumigatus	33.75	4.00e-07	49.30
IUUC-Bta-013571	Bos taurus	97.95	0.00e+00	634.00
IUUC-Cpo-022093	Cavia porcellus	90.97	1.00e-173	603.00
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	3.00e-11	62.80
IUUC-Csa-023627	Chlorocebus sabaeus	97.14	0.00e+00	638.00
IUUC-Cho-024552	Choloepus hoffmanni	91.91	4.00e-175	607.00
IUUC-Cne-026833	Cryptococcus neoformans	26.64	3.00e-13	69.70
IUUC-Dno-029647	Dasypus novemcinctus	94.47	0.00e+00	649.00
IUUC-Ete-033071	Echinops telfairi	88.34	0.00e+00	726.00
IUUC-Eeu-034727	Erinaceus europaeus	94.26	5.00e-176	610.00
IUUC-Fca-035803	Felis catus	99.10	0.00e+00	629.00
IUUC-Hsa-046768	Homo sapiens	97.52	6.00e-178	617.00
IUUC-Itr-048556	Ictidomys tridecemlineatus	91.48	5.00e-174	604.00
IUUC-Mor-057194	Magnaporthe oryzae	49.02	1.00e-07	51.20
IUUC-Mmr-061605	Microcebus murinus	95.94	4.00e-171	594.00
IUUC-Mpu-066474	Mustela putorius furo	99.10	0.00e+00	650.00
IUUC-Mlu-067252	Myotis lucifugus	88.09	4.00e-165	575.00
IUUC-Nfi-068487	Neosartorya fischeri	33.75	2.00e-07	50.40
IUUC-Nle-069038	Nomascus leucogenys	97.52	1.00e-178	619.00
IUUC-Oga-088005	Otolemur garnettii	97.07	6.00e-178	617.00
IUUC-Oar-089878	Ovis aries	97.74	0.00e+00	633.00
IUUC-Ptr-090781	Pan troglodytes	97.52	2.00e-178	619.00
IUUC-Pan-091716	Papio anubis	96.93	4.00e-179	621.00
IUUC-Pab-097891	Pongo abelii	97.74	3.00e-178	618.00
IUUC-Pca-100227	Procavia capensis	95.78	3.00e-95	342.00
IUUC-Tsy-119008	Tarsius syrichta	94.44	2.00e-166	579.00
IUUC-Vda-129991	Verticillium dahliae	46.15	3.00e-07	49.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence