iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074520

Ensembl Protein ID

ENSOCUP00000017169.1

UniProt Accession

G1TJP0; G1TJP0_RABIT

Genbank Protein ID

ENSOCUP00000017169

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02064532

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000025886.1	ENSOCUT00000025961.1	ENSOCUP00000017169.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.50e-10	40.9	529	566
ULD/UDP/UBQ/UBQ_PIM	7.10e-24	83.6	23	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 529  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 566
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 23   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLMQHGIHDGLTVHLVIKSQN 96
           69**********.***********************************************************986 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAENGESGAA QGSAATPAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA ISKRFKSQTD 60
QLVLIFAGKI LKDQDTLMQH GIHDGLTVHL VIKSQNRPQG QSSTQASSAA GTTTTSASTP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ACGGCGAAAG CAGCGGCCCC CCGCGCCCCT CCCGCGGCCC TGGTGCGGCC 60
CAAGGCTCGG CCGCCACACC AGCCGAGCCC AAAATCATTA AAGTCACTGT GAAGACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002068	Ailuropoda melanoleuca	94.79	0.00e+00	681.00
IUUC-Cpo-022093	Cavia porcellus	96.30	2.00e-172	598.00
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	2.00e-11	63.50
IUUC-Dno-029647	Dasypus novemcinctus	91.71	3.00e-158	551.00
IUUC-Eeu-034727	Erinaceus europaeus	88.05	2.00e-165	575.00
IUUC-Fso-038204	Fusarium solani	42.25	2.00e-08	53.50
IUUC-Ggo-044519	Gorilla gorilla	97.21	0.00e+00	695.00
IUUC-Hvu-047094	Hordeum vulgare	50.98	4.00e-09	53.10
IUUC-Mcc-054658	Macaca mulatta	92.28	0.00e+00	680.00
IUUC-Oga-088005	Otolemur garnettii	97.46	6.00e-166	577.00
IUUC-Pan-091716	Papio anubis	93.02	0.00e+00	691.00
IUUC-Pca-100227	Procavia capensis	96.89	1.00e-86	313.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Tsy-119008	Tarsius syrichta	95.38	8.00e-169	587.00
IUUC-Vda-129991	Verticillium dahliae	46.15	8.00e-07	48.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence