iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004412

UUCD1 version

UUC-AnC-00173

Ensembl Protein ID

ENSACAP00000012327.2

UniProt Accession

H9GJ13; H9GJ13_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TRIM62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000012575.2	ENSACAT00000012580.2	ENSACAP00000012327.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.60e-06	27.3	6	77
E3 activity/RING/RING	1.80e-07	31.5	11	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk......tcPvtrqplteedlvPnltlrrliqaw 68
            +e+lCpI l l +dPv   + + + r++I+++ ++++        cP +r++++e  l P+l l ++++++
   Q: 6    KDELLCPICLSLYQDPVSFGCEHYFCRRCIAEHWSRQEAqaaparDCPECRRTFSEPLLAPSLKLANIVERY 77
           689******************************988888899999*****************9999998877 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ ++d p++ +C H f++ C+ ++w  +  ++ ++  CP Cr
   Q: 11   CPICLSLYQD-PVSFGCEHYFCRRCIaEHWSRQEAQAAPARDCPECR 56
           **********.999****************777777888888****8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

SCCSLKDELL CPICLSLYQD PVSFGCEHYF CRRCIAEHWS RQEAQAAPAR DCPECRRTFS 60
EPLLAPSLKL ANIVERYAAF PLDALLRSAS ARLASSEHDK VQLFCLSDRA GVCFCDEPAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGTGCTGCA GCCTGAAGGA CGAGCTGCTC TGCCCGATCT GCCTGAGCCT GTACCAGGAC 60
CCGGTCAGCT TTGGCTGCGA GCACTACTTC TGCCGGCGCT GCATCGCGGA GCACTGGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0032897--P:negative regulation of viral transcription
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046596--P:regulation of viral entry into host cell
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002199	Ailuropoda melanoleuca	84.34	0.00e+00	807.00
IUUC-Apl-003767	Anas platyrhynchos	83.56	0.00e+00	740.00
IUUC-Ame-010927	Astyanax mexicanus	77.18	0.00e+00	779.00
IUUC-Bta-012927	Bos taurus	84.34	0.00e+00	806.00
IUUC-Cja-019317	Callithrix jacchus	78.91	0.00e+00	727.00
IUUC-Cfa-020292	Canis familiaris	90.29	0.00e+00	655.00
IUUC-Cpo-022274	Cavia porcellus	91.20	0.00e+00	657.00
IUUC-Csa-023042	Chlorocebus sabaeus	84.34	0.00e+00	807.00
IUUC-Dre-028493	Danio rerio	77.50	0.00e+00	777.00
IUUC-Dno-030029	Dasypus novemcinctus	80.58	0.00e+00	754.00
IUUC-Dor-031051	Dipodomys ordii	82.53	0.00e+00	767.00
IUUC-Ete-032752	Echinops telfairi	90.11	2.00e-101	362.00
IUUC-Eca-033898	Equus caballus	71.14	0.00e+00	740.00
IUUC-Eeu-034659	Erinaceus europaeus	90.38	2.00e-77	281.00
IUUC-Fca-035492	Felis catus	81.42	0.00e+00	803.00
IUUC-Fal-036867	Ficedula albicollis	82.72	0.00e+00	786.00
IUUC-Gmo-038916	Gadus morhua	77.18	0.00e+00	748.00
IUUC-Gga-040360	Gallus gallus	85.62	0.00e+00	814.00
IUUC-Gac-041871	Gasterosteus aculeatus	77.80	0.00e+00	785.00
IUUC-Ggo-044411	Gorilla gorilla	77.92	0.00e+00	731.00
IUUC-Hsa-047025	Homo sapiens	83.92	0.00e+00	830.00
IUUC-Itr-047905	Ictidomys tridecemlineatus	84.34	0.00e+00	807.00
IUUC-Loc-052114	Lepisosteus oculatus	79.46	0.00e+00	800.00
IUUC-Laf-054359	Loxodonta africana	81.51	4.00e-173	600.00
IUUC-Mcc-055563	Macaca mulatta	84.34	0.00e+00	807.00
IUUC-Meu-056027	Macropus eugenii	67.22	7.00e-180	623.00
IUUC-Mga-060146	Meleagris gallopavo	68.00	2.00e-54	204.00
IUUC-Mmr-060822	Microcebus murinus	84.34	0.00e+00	806.00
IUUC-Mdo-062117	Monodelphis domestica	68.72	2.00e-156	545.00
IUUC-Mmu-064086	Mus musculus	84.13	0.00e+00	806.00
IUUC-Mpu-066378	Mustela putorius furo	84.34	0.00e+00	807.00
IUUC-Mlu-067155	Myotis lucifugus	83.12	0.00e+00	812.00
IUUC-Nle-069464	Nomascus leucogenys	84.13	0.00e+00	806.00
IUUC-Opr-071058	Ochotona princeps	91.40	2.00e-125	442.00
IUUC-Ont-071253	Oreochromis niloticus	70.12	0.00e+00	678.00
IUUC-Oan-073614	Ornithorhynchus anatinus	94.94	7.00e-92	328.00
IUUC-Ola-086794	Oryzias latipes	77.71	0.00e+00	777.00
IUUC-Oga-088889	Otolemur garnettii	84.13	0.00e+00	806.00
IUUC-Oar-089203	Ovis aries	84.45	0.00e+00	743.00
IUUC-Ptr-090795	Pan troglodytes	84.13	0.00e+00	832.00
IUUC-Pfo-096942	Poecilia formosa	76.76	0.00e+00	769.00
IUUC-Pab-097936	Pongo abelii	74.67	1.00e-158	551.00
IUUC-Pca-100397	Procavia capensis	83.51	0.00e+00	800.00
IUUC-Ppe-101916	Prunus persica	32.63	3.00e-10	60.80
IUUC-Pva-102293	Pteropus vampyrus	90.56	0.00e+00	638.00
IUUC-Rno-105551	Rattus norvegicus	83.92	0.00e+00	803.00
IUUC-Ssc-115983	Sus scrofa	84.34	0.00e+00	807.00
IUUC-Tgu-117279	Taeniopygia guttata	70.02	9.00e-171	592.00
IUUC-Tru-118238	Takifugu rubripes	77.18	0.00e+00	777.00
IUUC-Tni-119788	Tetraodon nigroviridis	57.29	1.00e-139	489.00
IUUC-Vvi-131261	Vitis vinifera	31.82	1.00e-08	55.80
IUUC-Xtr-132768	Xenopus tropicalis	67.18	0.00e+00	642.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence