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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018670
Ensembl Protein ID F23B2.4
UniProt Accession G5EFW7; IF122_CAEEL
Genbank Protein ID ABC88647.1; CAB05177.4
Protein Name Intraflagellar transport protein 122 homolog; Abnormal dauer formation protein 10
Genbank Nucleotide ID DQ360810; BX284604
Gene Name daf-10; F23B2.4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00000906 F23B2.4 F23B2.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
IID
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.20e-12 47.9 58 88
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+d v+ +a+ ++  l++sG+ D+ + +W+
   Q: 58   GHKDLVYTVAWsHNgELFASGGADKLVILWN 88
           8**********9545***************8 PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Plays a role in chemotaxis and sensory perception (PubMed:7240452, PubMed:7705621). Required for entry into and exit from the dauer larval stage and this may be mediated by daf-12, daf-16 and daf-41 (PubMed:7240452, PubMed:23284299, PubMed:25830239). Controls the behavioral response, namely the avoidance response, and pathogen-responsive gene expression in the response to pathogenic bacteria such as E.coli and P. aeruginosa (PubMed:23284299).
 Plays a role in chemotaxis and sensory perception (PubMed:7240452, PubMed:7705621). Required for entry into and exit from the dauer larval stage and this may be mediated by daf-12, daf-16 and daf-41 (PubMed:7240452, PubMed:23284299, PubMed:25830239). Controls the behavioral response, namely the avoidance response, and pathogen-responsive gene expression in the response to pathogenic bacteria such as E.coli and P. aeruginosa (PubMed:23284299).
Protein Sequence
(Fasta)
MRPNLLWVDK ILDENNEAGV CIYDLAFKPD GSELLLAADN KVYLFDVNEG GQMQTLKGHK 60
DLVYTVAWSH NGELFASGGA DKLVILWNEK HEGTLRYSHT DVIQCMMFNP CNQILLTCAL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018670|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACTTATTTTA TAAAATGCGA CCAAATTTAC TATGGGTCGA CAAAATTTTA GACGAAAACA 60
ATGAAGCTGG GTGAGTTGTT TAAAATTTCA AAATATTTCT TTCATTTTCA AAAACAAATG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018670|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0966--Cell projection
KW-0145--Chemotaxis
KW-0969--Cilium
KW-0181--Complete proteome
KW-0282--Flagellum
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0036064--C:ciliary basal body
GO:0005929--C:cilium
GO:0030991--C:intraciliary transport particle A
GO:0031514--C:motile cilium
GO:0006935--P:chemotaxis
GO:0060271--P:cilium assembly
GO:0035721--P:intraciliary retrograde transport
GO:1905515--P:non-motile cilium assembly
GO:0061066--P:positive regulation of dauer larval development
GO:0097500--P:receptor localization to non-motile cilium
GO:0061065--P:regulation of dauer larval development
GO:0046626--P:regulation of insulin receptor signaling pathway
KEGG cel:CELE_F23B2.4
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001933 Ailuropoda melanoleuca 38.15 0.00e+00 910.00
IUUC-Apl-003504 Anas platyrhynchos 39.04 0.00e+00 924.00
IUUC-Aca-004767 Anolis carolinensis 37.55 0.00e+00 896.00
IUUC-Ame-011642 Astyanax mexicanus 36.11 0.00e+00 867.00
IUUC-Bta-012969 Bos taurus 37.54 0.00e+00 885.00
IUUC-Cja-019249 Callithrix jacchus 36.78 0.00e+00 843.00
IUUC-Cfa-020915 Canis familiaris 39.02 0.00e+00 763.00
IUUC-Cpo-021888 Cavia porcellus 38.56 0.00e+00 921.00
IUUC-Cre-022789 Chlamydomonas reinhardtii 34.63 0.00e+00 741.00
IUUC-Csa-023533 Chlorocebus sabaeus 38.20 0.00e+00 895.00
IUUC-Cin-025121 Ciona intestinalis 37.49 0.00e+00 870.00
IUUC-Csv-026240 Ciona savignyi 36.09 0.00e+00 832.00
IUUC-Dno-029685 Dasypus novemcinctus 39.30 0.00e+00 917.00
IUUC-Ete-032682 Echinops telfairi 35.51 0.00e+00 667.00
IUUC-Eca-033831 Equus caballus 38.36 0.00e+00 922.00
IUUC-Eeu-034919 Erinaceus europaeus 34.96 4.00e-106 378.00
IUUC-Fca-036559 Felis catus 38.36 0.00e+00 907.00
IUUC-Fal-037340 Ficedula albicollis 39.24 0.00e+00 924.00
IUUC-Gga-040595 Gallus gallus 39.19 0.00e+00 940.00
IUUC-Ggo-045356 Gorilla gorilla 36.53 0.00e+00 869.00
IUUC-Hsa-046135 Homo sapiens 36.55 0.00e+00 868.00
IUUC-Itr-048228 Ictidomys tridecemlineatus 38.37 0.00e+00 738.00
IUUC-Lch-050183 Latimeria chalumnae 36.17 9.00e-140 489.00
IUUC-Loc-052049 Lepisosteus oculatus 38.91 0.00e+00 933.00
IUUC-Laf-053728 Loxodonta africana 38.14 0.00e+00 917.00
IUUC-Mcc-054971 Macaca mulatta 36.96 0.00e+00 874.00
IUUC-Meu-056446 Macropus eugenii 36.16 4.00e-140 491.00
IUUC-Mga-059296 Meleagris gallopavo 38.00 0.00e+00 753.00
IUUC-Mmr-061232 Microcebus murinus 36.72 0.00e+00 857.00
IUUC-Mdo-062115 Monodelphis domestica 38.16 0.00e+00 911.00
IUUC-Mmu-063664 Mus musculus 38.46 0.00e+00 921.00
IUUC-Mpu-066136 Mustela putorius furo 37.44 0.00e+00 883.00
IUUC-Mlu-068238 Myotis lucifugus 38.46 0.00e+00 893.00
IUUC-Nle-069003 Nomascus leucogenys 37.18 0.00e+00 824.00
IUUC-Ont-072080 Oreochromis niloticus 36.93 0.00e+00 897.00
IUUC-Oan-072891 Ornithorhynchus anatinus 38.48 2.00e-113 401.00
IUUC-Ocu-074262 Oryctolagus cuniculus 37.45 0.00e+00 867.00
IUUC-Ola-086538 Oryzias latipes 37.71 0.00e+00 747.00
IUUC-Oga-088722 Otolemur garnettii 38.33 0.00e+00 733.00
IUUC-Oar-089249 Ovis aries 38.69 0.00e+00 911.00
IUUC-Ptr-090752 Pan troglodytes 36.94 0.00e+00 793.00
IUUC-Pan-092472 Papio anubis 38.22 0.00e+00 895.00
IUUC-Psi-093335 Pelodiscus sinensis 39.77 0.00e+00 939.00
IUUC-Pma-094520 Petromyzon marinus 36.40 0.00e+00 798.00
IUUC-Ppa-095600 Physcomitrella patens 46.90 1.00e-30 124.00
IUUC-Pfo-096526 Poecilia formosa 36.88 0.00e+00 864.00
IUUC-Pab-098428 Pongo abelii 38.08 4.00e-129 454.00
IUUC-Pca-100233 Procavia capensis 36.72 2.00e-85 309.00
IUUC-Pva-103064 Pteropus vampyrus 32.66 2.00e-112 399.00
IUUC-Rno-105764 Rattus norvegicus 38.42 0.00e+00 915.00
IUUC-Sha-106649 Sarcophilus harrisii 37.80 0.00e+00 905.00
IUUC-Smo-109478 Selaginella moellendorffii 30.69 3.00e-168 584.00
IUUC-Tgu-116870 Taeniopygia guttata 36.98 0.00e+00 850.00
IUUC-Tru-118661 Takifugu rubripes 35.40 0.00e+00 850.00
IUUC-Tsy-119640 Tarsius syrichta 37.81 1.00e-41 164.00
IUUC-Tni-120812 Tetraodon nigroviridis 35.89 0.00e+00 862.00
IUUC-Ttr-128862 Tursiops truncatus 36.56 0.00e+00 873.00
IUUC-Vpa-130049 Vicugna pacos 29.91 9.00e-50 191.00
IUUC-Xtr-131914 Xenopus tropicalis 37.93 0.00e+00 879.00
Created Date 25-Jun-2017

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