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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063722
UUCD1 version UUC-MuM-00837
Ensembl Protein ID ENSMUSP00000036472.7
UniProt Accession Q91XF4; Q3U4S5; RN167_MOUSE
Genbank Protein ID BAE32356.1; CAI25167.1; AAH10777.1
Protein Name E3 ubiquitin-protein ligase RNF167; RING finger protein 167; RING-type E3 ubiquitin transferase RNF167
Genbank Nucleotide ID AK154071; AL596117; BC010777
Gene Name Rnf167
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000040746.15 ENSMUST00000141695.7 ENSMUSP00000121511.1
ENSMUSG00000040746.15 ENSMUST00000037534.7 ENSMUSP00000036472.7
ENSMUSG00000040746.15 ENSMUST00000152160.7 ENSMUSP00000115057.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
miRTarBasemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 3.20e-09 38.3 230 272
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl++++dg  ++vlpC H++h  C+  w     +++++ +CP+C+
   Q: 230  CAICLDEYEDGdkLRVLPCAHAYHSRCVDPW-----LTQTRKTCPICK 272
           ********66666******************.....8**********7 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
 May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
Protein Sequence
(Fasta)
MHPAAFPLPV VVATVLWGAA PVRGLIRATS EHNASMDFAD LPALFGATLS DEGLQGFLVE 60
AHPENACGPI APPPSAPVNG SVFIALLRRF DCNFDLKVLN AQKAGYGAAV VHNVNSNELL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063722|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGTGGGGGGG TGGAGGGAGG GTGGTGGCAA GCACTCTCGC GATACTTTGA ACGTACCGTG 60
GCGGCCAGAC GAAGGAGAGG TTTGTAAACA GGGCAGCTCC AGGATCTCAG GGACTGAGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063722|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF02225--PA
PF13639--zf-RING_2
SMART

SM00184--RING
SM00744--RINGv
Gene Ontology

GO:0005737--C:cytoplasm
GO:0012505--C:endomembrane system
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045786--P:negative regulation of cell cycle
GO:0000209--P:protein polyubiquitination
KEGG mmu:70510
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001413 Ailuropoda melanoleuca 86.79 2.00e-133 468.00
IUUC-Acl-008256 Aspergillus clavatus 60.42 6.00e-14 71.60
IUUC-Afl-008548 Aspergillus flavus 62.22 9.00e-14 70.90
IUUC-Afu-008977 Aspergillus fumigatus 62.22 2.00e-13 70.50
IUUC-Ang-009734 Aspergillus niger 62.22 5.00e-14 72.40
IUUC-Aor-010134 Aspergillus oryzae 62.22 9.00e-14 71.20
IUUC-Ate-010329 Aspergillus terreus 62.22 2.00e-13 70.50
IUUC-Bgr-012220 Blumeria graminis 55.56 2.00e-12 67.40
IUUC-Bta-012651 Bos taurus 93.86 1.00e-125 442.00
IUUC-Bci-013726 Botrytis cinerea 55.56 1.00e-12 68.20
IUUC-Bdi-014989 Brachypodium distachyon 31.19 1.00e-33 137.00
IUUC-Cja-018953 Callithrix jacchus 90.35 4.00e-144 504.00
IUUC-Cfa-020540 Canis familiaris 72.05 4.00e-95 341.00
IUUC-Cpo-022372 Cavia porcellus 93.05 6.00e-169 586.00
IUUC-Cre-022631 Chlamydomonas reinhardtii 28.37 8.00e-24 104.00
IUUC-Csa-023070 Chlorocebus sabaeus 91.00 2.00e-156 545.00
IUUC-Csv-025959 Ciona savignyi 44.87 8.00e-52 197.00
IUUC-Cgl-026762 Colletotrichum gloeosporioides 60.00 1.00e-13 71.20
IUUC-Cne-026954 Cryptococcus neoformans 48.44 1.00e-13 71.20
IUUC-Dre-028786 Danio rerio 57.35 4.00e-81 295.00
IUUC-Dno-028877 Dasypus novemcinctus 93.05 1.00e-166 578.00
IUUC-Dor-030128 Dipodomys ordii 82.18 2.00e-150 525.00
IUUC-Ete-033067 Echinops telfairi 74.19 2.00e-105 375.00
IUUC-Eca-033699 Equus caballus 92.45 3.00e-156 544.00
IUUC-Eeu-034819 Erinaceus europaeus 92.90 9.00e-149 519.00
IUUC-Fca-036168 Felis catus 92.75 6.00e-146 509.00
IUUC-Fox-037990 Fusarium oxysporum 60.00 2.00e-13 70.50
IUUC-Fso-038278 Fusarium solani 60.00 4.00e-13 69.30
IUUC-Ggr-039870 Gaeumannomyces graminis 55.56 1.00e-12 68.20
IUUC-Gac-041339 Gasterosteus aculeatus 56.70 3.00e-79 288.00
IUUC-Gma-043776 Glycine max 31.94 4.00e-29 122.00
IUUC-Ggo-045113 Gorilla gorilla 91.00 5.00e-158 550.00
IUUC-Hsa-046476 Homo sapiens 94.84 2.00e-159 555.00
IUUC-Hvu-047136 Hordeum vulgare 33.21 2.00e-29 123.00
IUUC-Itr-047953 Ictidomys tridecemlineatus 91.24 1.00e-168 585.00
IUUC-Lch-050034 Latimeria chalumnae 62.20 3.00e-99 355.00
IUUC-Lpe-051192 Leersia perrieri 31.37 6.00e-29 122.00
IUUC-Loc-051914 Lepisosteus oculatus 65.71 2.00e-90 325.00
IUUC-Lma-053199 Leptosphaeria maculans 58.33 5.00e-14 72.00
IUUC-Laf-053687 Loxodonta africana 89.32 1.00e-149 522.00
IUUC-Mcc-055879 Macaca mulatta 94.84 4.00e-160 557.00
IUUC-Meu-056408 Macropus eugenii 77.90 5.00e-120 423.00
IUUC-Mor-057236 Magnaporthe oryzae 60.00 2.00e-13 70.90
IUUC-Mpo-057321 Magnaporthe poae 55.56 1.00e-12 67.80
IUUC-Mmr-060656 Microcebus murinus 93.05 6.00e-170 589.00
IUUC-Mdo-062795 Monodelphis domestica 88.09 7.00e-141 493.00
IUUC-Mac-065216 Musa acuminata 30.59 5.00e-31 129.00
IUUC-Mpu-066094 Mustela putorius furo 89.25 2.00e-145 508.00
IUUC-Mlu-067350 Myotis lucifugus 91.84 6.00e-153 533.00
IUUC-Nfi-068514 Neosartorya fischeri 62.22 2.00e-13 70.50
IUUC-Ncr-068771 Neurospora crassa 54.00 2.00e-13 70.50
IUUC-Nle-069971 Nomascus leucogenys 91.00 2.00e-156 544.00
IUUC-Opr-070716 Ochotona princeps 94.17 3.00e-109 388.00
IUUC-Oan-072710 Ornithorhynchus anatinus 72.00 7.00e-69 253.00
IUUC-Ocu-074157 Oryctolagus cuniculus 90.68 2.00e-156 545.00
IUUC-Oba-075841 Oryza barthii 30.56 4.00e-28 119.00
IUUC-Obr-076703 Oryza brachyantha 31.68 3.00e-30 126.00
IUUC-Ogl-077861 Oryza glaberrima 32.57 3.00e-30 126.00
IUUC-Oin-080138 Oryza indica 32.69 3.00e-29 122.00
IUUC-Olo-081024 Oryza longistaminata 31.91 3.00e-29 124.00
IUUC-Ome-081844 Oryza meridionalis 32.57 4.00e-30 125.00
IUUC-Oni-082422 Oryza nivara 32.69 4.00e-29 122.00
IUUC-Opu-083162 Oryza punctata 33.33 1.00e-32 134.00
IUUC-Oru-085122 Oryza rufipogon 32.24 8.00e-27 115.00
IUUC-Osa-086175 Oryza sativa 32.57 3.00e-30 126.00
IUUC-Oga-089169 Otolemur garnettii 91.27 9.00e-170 589.00
IUUC-Oar-089216 Ovis aries 93.66 5.00e-154 536.00
IUUC-Ptr-091493 Pan troglodytes 91.00 5.00e-158 550.00
IUUC-Pan-092215 Papio anubis 90.68 4.00e-156 543.00
IUUC-Psi-093038 Pelodiscus sinensis 60.93 3.00e-109 388.00
IUUC-Pno-094907 Phaeosphaeria nodorum 62.22 4.00e-14 72.40
IUUC-Pfo-097514 Poecilia formosa 58.85 6.00e-83 300.00
IUUC-Pab-097739 Pongo abelii 84.48 2.00e-152 531.00
IUUC-Pca-100609 Procavia capensis 91.24 1.00e-154 539.00
IUUC-Pva-102834 Pteropus vampyrus 90.94 1.00e-164 572.00
IUUC-Pte-104147 Pyrenophora teres 60.00 1.00e-13 70.90
IUUC-Pyt-104748 Pyrenophora triticirepentis 62.22 1.00e-13 71.20
IUUC-Rno-106080 Rattus norvegicus 95.48 1.00e-170 592.00
IUUC-Sha-106787 Sarcophilus harrisii 86.28 3.00e-137 481.00
IUUC-Spo-108205 Schizosaccharomyces pombe 41.67 9.00e-11 60.80
IUUC-Ssl-108451 Sclerotinia sclerotiorum 55.56 1.00e-12 67.80
IUUC-Sit-110044 Setaria italica 33.21 7.00e-30 125.00
IUUC-Sar-113580 Sorex araneus 77.95 1.00e-121 429.00
IUUC-Sbi-114522 Sorghum bicolor 33.55 5.00e-28 119.00
IUUC-Ssc-115900 Sus scrofa 93.66 1.00e-169 588.00
IUUC-Tsy-119134 Tarsius syrichta 93.63 2.00e-94 338.00
IUUC-Tni-120357 Tetraodon nigroviridis 59.35 1.00e-86 313.00
IUUC-Tca-121333 Theobroma cacao 31.84 2.00e-29 122.00
IUUC-Tre-121885 Trichoderma reesei 57.78 8.00e-13 68.20
IUUC-Tvi-122633 Trichoderma virens 57.78 9.00e-13 68.20
IUUC-Tae-125403 Triticum aestivum 33.33 6.00e-33 135.00
IUUC-Tme-127069 Tuber melanosporum 57.78 1.00e-12 67.80
IUUC-Tbe-127812 Tupaia belangeri 94.20 2.00e-127 447.00
IUUC-Ttr-128409 Tursiops truncatus 93.48 4.00e-129 454.00
IUUC-Vvi-131036 Vitis vinifera 31.98 1.00e-31 130.00
IUUC-Xma-133568 Xiphophorus maculatus 56.51 2.00e-77 283.00
Created Date 25-Jun-2017

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